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    Method for preparing novel processed ginseng or an extract thereof, the usually minute ginsenoside content of which is increased
    3.
    发明授权
    Method for preparing novel processed ginseng or an extract thereof, the usually minute ginsenoside content of which is increased 有权
    制备新加工人参的方法或其提取物，其通常分钟人参皂苷含量增加

    公开(公告)号：US09512453B2

    公开(公告)日：2016-12-06

    申请号：US13698005

    申请日：2011-05-13

    申请人： Young-Hyo Yoo ,  Sun-Ok Kim ,  Jung Hyo Choi ,  Soo-Hyun Bae ,  Sun Kyu Park ,  Jeom Yong Kim

    发明人： Young-Hyo Yoo ,  Sun-Ok Kim ,  Jung Hyo Choi ,  Soo-Hyun Bae ,  Sun Kyu Park ,  Jeom Yong Kim

    IPC分类号： A61K31/513 ,  C12P19/14 ,  A61K36/258 ,  A61K31/282 ,  A61K31/519 ,  A61K45/06

    CPC分类号： C12P19/14 ,  A61K31/282 ,  A61K31/513 ,  A61K31/519 ,  A61K36/258 ,  A61K45/06 ,  A61K2236/19

    摘要： A method for preparing a processed ginseng or a processed ginseng extract having increased contents of ginsenosides Rg3 and Rh2 by (a) inoculating an Aspergillus niger strain into a medium composed of ginseng and wheat bran; (b) culturing the strain of step (a); (c) purifying the cultured material of step (b) by ultrafiltration; (d) separating an enzyme from the purified material of step (c); (e) adding the enzyme of step (d) to ginseng or red ginseng; (f) fermenting the ginseng or red ginseng of step (e); (g) separating the fermented material of step (f) to obtain a supernatant; (h) concentrating the supernatant of step (g); (i) reacting the concentrate of step (h) with organic acid; and (j) neutralizing, filtering, purifying, concentrating and drying the reaction product of step (i).

    摘要翻译： 一种通过（a）将黑曲霉菌株接种到由人参和麦麸组成的培养基中制备人参或加工人参提取物的方法，其具有增加的人参皂甙Rg3和Rh2的含量; （b）培养步骤（a）的菌株; （c）通过超滤纯化步骤（b）的培养物质; （d）从步骤（c）的纯化物质中分离酶; （e）将步骤（d）的酶加入人参或红参中; （f）发酵步骤（e）的人参或红参; （g）分离步骤（f）的发酵物质，得到上清液; （h）浓缩步骤（g）的上清液; （i）使步骤（h）的浓缩物与有机酸反应; 和（j）中和，过滤，纯化，浓缩和干燥步骤（i）的反应产物。