公开(公告)号：US20240360422A1

公开(公告)日：2024-10-31

申请号：US18287734

申请日：2022-04-21

Applicant: MICHAEL T. LEONARD ,  Jeremy j. Gam ,  Christopher S. Stach ,  Alec A.K. Nielsen

Inventor： MICHAEL T. LEONARD ,  Jeremy j. Gam ,  Christopher S. Stach ,  Alec A.K. Nielsen

IPC: C12N7/00 ,  C07K14/005 ,  C07K14/435 ,  C12N9/00 ,  C12N15/86

CPC classification number: C12N7/00 ,  C07K14/005 ,  C07K14/435 ,  C12N9/93 ,  C12N15/86 ,  C12Y601/01026 ,  C12N2750/14122 ,  C12N2750/14143 ,  C12N2750/14152

Abstract: Disclosed herein are cell genetically engineered cell for AAV production. The genetically engineered cell comprises molecular systems for temporal control of expression of genes required for AAV production. Also disclosed herein are methods of using genetically engineered cells for AAV production.