公开(公告)号：US20140287959A1

公开(公告)日：2014-09-25

申请号：US14129233

申请日：2012-04-03

申请人： Adam B. Braunschweig ,  Jiajun He ,  Shudan Bian ,  Kevin B. Schesing

发明人： Adam B. Braunschweig ,  Jiajun He ,  Shudan Bian ,  Kevin B. Schesing

IPC分类号： B01J19/00

CPC分类号： B01J19/0046 ,  B01J2219/00382 ,  B01J2219/00387 ,  B01J2219/00527 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/00612 ,  B01J2219/00626 ,  B01J2219/00632 ,  B01J2219/0065 ,  B01J2219/00659 ,  B82Y15/00

摘要： Polymer Pen Lithography is used to induce bioorthogonal reactions between treated surfaces and functionalized inks create a soft matter layer. Fluorescent and redox-active inks were used to demonstrate that the molecules were immobilized covalently and achieves precise control over ligand orientation and density within each feature. Finally, the utility was demonstrated by creating functional arrays of biologically active probes.

摘要翻译： 聚合物笔平版印刷术用于诱导处理过的表面之间的生物正交反应，功能化油墨产生软质层。 使用荧光和氧化还原活性油墨来证明分子被共价固定，并且在每个特征内实现配体取向和密度的精确控制。 最后，通过创建生物活性探针的功能阵列证明了实用性。