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公开(公告)号:US08143232B2
公开(公告)日:2012-03-27
申请号:US12716653
申请日:2010-03-03
申请人: Arul M. Chinnaiyan , Jindan Yu , Ram Shankar Mani
发明人: Arul M. Chinnaiyan , Jindan Yu , Ram Shankar Mani
CPC分类号: A61K31/7105 , C12N15/1135 , C12N2310/14
摘要: The present invention relates to compositions and methods for cancer therapy, including but not limited to, targeted inhibition of cancer markers. In particular, the present invention relates to recurrent gene fusions as clinical targets for prostate cancer.
摘要翻译: 本发明涉及用于癌症治疗的组合物和方法,包括但不限于癌症标志物的靶向抑制。 特别地,本发明涉及作为前列腺癌的临床靶标的复发性基因融合体。
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公开(公告)号:US08058003B2
公开(公告)日:2011-11-15
申请号:US12016498
申请日:2008-01-18
申请人: Arul M. Chinnaiyan , Jindan Yu , Rohit Mehra
发明人: Arul M. Chinnaiyan , Jindan Yu , Rohit Mehra
CPC分类号: C12Q1/6886 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158
摘要: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ADRB2 markers for cancer.
摘要翻译: 本发明涉及用于癌症诊断,研究和治疗的组合物和方法,包括但不限于癌症标志物。 特别地,本发明涉及用于癌症的ADRB2标志物。
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公开(公告)号:US20090075833A1
公开(公告)日:2009-03-19
申请号:US12016498
申请日:2008-01-18
申请人: Arul M. Chinnaiyan , Jindan Yu , Rohit Mehra
发明人: Arul M. Chinnaiyan , Jindan Yu , Rohit Mehra
CPC分类号: C12Q1/6886 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158
摘要: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ADRB2 markers for cancer.
摘要翻译: 本发明涉及用于癌症诊断,研究和治疗的组合物和方法,包括但不限于癌症标志物。 特别地,本发明涉及用于癌症的ADRB2标志物。
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公开(公告)号:US20100227910A1
公开(公告)日:2010-09-09
申请号:US12716653
申请日:2010-03-03
申请人: Arul M. Chinnaiyan , Jindan Yu , Ram Shankar Mani
发明人: Arul M. Chinnaiyan , Jindan Yu , Ram Shankar Mani
IPC分类号: A61K31/7105 , C12N5/071 , C07H21/02 , A61P35/00
CPC分类号: A61K31/7105 , C12N15/1135 , C12N2310/14
摘要: The present invention relates to compositions and methods for cancer therapy, including but not limited to, targeted inhibition of cancer markers. In particular, the present invention relates to recurrent gene fusions as clinical targets for prostate cancer.
摘要翻译: 本发明涉及用于癌症治疗的组合物和方法,包括但不限于癌症标志物的靶向抑制。 特别地,本发明涉及作为前列腺癌的临床靶标的复发性基因融合体。
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公开(公告)号:US20100055688A1
公开(公告)日:2010-03-04
申请号:US12388058
申请日:2009-02-18
申请人: Arul M. Chinnaiyan , Jindan Yu
发明人: Arul M. Chinnaiyan , Jindan Yu
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6886 , C12Q2600/118 , C12Q2600/136
摘要: This invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, this invention relates to SLIT2 cancer markers that are useful as diagnostic markers and clinical targets for prostate cancer.
摘要翻译: 本发明涉及用于癌症诊断,研究和治疗的组合物和方法,包括但不限于癌症标志物。 特别地,本发明涉及可用作诊断标记物和用于前列腺癌的临床靶标的SLIT2癌症标志物。
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公开(公告)号:US08900819B2
公开(公告)日:2014-12-02
申请号:US13286820
申请日:2011-11-01
申请人: Arul M. Chinnaiyan , Jindan Yu , Rohit Mehra
发明人: Arul M. Chinnaiyan , Jindan Yu , Rohit Mehra
IPC分类号: G01N33/53 , G01N33/566 , C12Q1/68 , C07K16/00 , C12P21/08
CPC分类号: C12Q1/6886 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158
摘要: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ADRB2 markers for cancer.
摘要翻译: 本发明涉及用于癌症诊断,研究和治疗的组合物和方法,包括但不限于癌症标志物。 特别地,本发明涉及用于癌症的ADRB2标志物。
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公开(公告)号:US20120046196A1
公开(公告)日:2012-02-23
申请号:US13286820
申请日:2011-11-01
申请人: Arul M. Chinnaiyan , Jindan Yu , Rohit Mehra
发明人: Arul M. Chinnaiyan , Jindan Yu , Rohit Mehra
CPC分类号: C12Q1/6886 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158
摘要: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ADRB2 markers for cancer.
摘要翻译: 本发明涉及用于癌症诊断,研究和治疗的组合物和方法,包括但不限于癌症标志物。 特别地,本发明涉及用于癌症的ADRB2标志物。
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公开(公告)号:US07968294B2
公开(公告)日:2011-06-28
申请号:US12388058
申请日:2009-02-18
申请人: Arul M. Chinnaiyan , Jindan Yu
发明人: Arul M. Chinnaiyan , Jindan Yu
IPC分类号: C12Q1/68 , G01N33/53 , G01N33/574
CPC分类号: C12Q1/6886 , C12Q2600/118 , C12Q2600/136
摘要: This invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, this invention relates to SLIT2 cancer markers that are useful as diagnostic markers and clinical targets for prostate cancer.
摘要翻译: 本发明涉及用于癌症诊断,研究和治疗的组合物和方法,包括但不限于癌症标志物。 特别地,本发明涉及可用作诊断标记物和用于前列腺癌的临床靶标的SLIT2癌症标志物。
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