公开(公告)号：US08221348B2

公开(公告)日：2012-07-17

申请号：US11177473

申请日：2005-07-07

申请人： Steven S. Hackett ,  Eric S. Stainbrook ,  Thomas F. Janecek ,  Chad W. Trembath ,  Andrew J. Dusbabek ,  John R. Drontle ,  Joel D. Phillips ,  Thomas V. Ressemann ,  Kyle L. Thunstrom ,  Peter T. Keith

发明人： Steven S. Hackett ,  Eric S. Stainbrook ,  Thomas F. Janecek ,  Chad W. Trembath ,  Andrew J. Dusbabek ,  John R. Drontle ,  Joel D. Phillips ,  Thomas V. Ressemann ,  Kyle L. Thunstrom ,  Peter T. Keith

IPC分类号： A61M29/00

CPC分类号： A61B17/22032 ,  A61M25/005 ,  A61M25/10181 ,  A61M2025/0034 ,  A61M2025/0037 ,  A61M2205/8225

摘要： An evacuation sheath assembly and method of reducing or removing a blockage within a vessel without permitting embolization of particulate matter is provided. The evacuation sheath assembly includes a first elongate tubular member, having proximal and distal ends and a main lumen configured to be placed in fluid communication with a blood vessel. An expandable member is provided on a distal portion of the tubular member and is configured to form a seal with the blood vessel. The evacuation assembly further includes a second elongate tubular member having proximal and distal ends and an inflation lumen configured to be placed in fluid communication with the expandable member and a gas inflator. The gas inflator includes a high pressure gas source and a mechanism for regulating the pressure of the gas delivered by the gas inflator. The gas inflator is configured to be placed in fluid communication with the proximal end of the inflation lumen in order to provide a regulated pressure gas source for inflating the expandable member. A method of treatment of a blood vessel using the evacuation sheath assembly includes advancing the evacuation sheath assembly into the blood vessel through a guide catheter. The expandable member is inflated to provide form a seal between the blood vessel and the guide catheter and a vacuum is applied to the main lumen of the first elongate tubular member to cause retrograde blood flow and carry fluid into the main lumen of the evacuation sheath assembly.

摘要翻译： 提供疏散护套组件以及在不允许颗粒物质栓塞的情况下减少或去除容器内的堵塞的方法。 抽真空组件包括第一细长管状构件，其具有近端和远端以及构造成与血管流体连通的主腔。 可膨胀构件设置在管状构件的远侧部分上并构造成与血管形成密封。 排气组件还包括具有近端和远端的第二细长管状构件和构造成与膨胀构件和气体充气器流体连通的膨胀腔。 气体充气机包括高压气体源和用于调节由气体充气机输送的气体的压力的机构。 气体充气器被配置成与膨胀腔的近端流体连通，以便提供用于使可膨胀构件膨胀的调节压力气体源。 使用排气鞘组件治疗血管的方法包括通过引导导管将排空鞘组件推进到血管中。 可膨胀构件被膨胀以在血管和引导导管之间形成密封，并且将真空施加到第一细长管状构件的主腔，以引起逆行血流并将流体携带到排泄鞘组件的主腔内 。

公开(公告)号：US07976564B2

公开(公告)日：2011-07-12

申请号：US10138565

申请日：2002-05-06

申请人： David J. Blaeser ,  Peter T. Keith ,  Jerome K. Grudem, Jr. ,  Scott A. Olson ,  Steven S. Hackett ,  Thomas V. Ressemann ,  Joel D. Phillips ,  Mark R. Christianson ,  Dennis W. Wahr

发明人： David J. Blaeser ,  Peter T. Keith ,  Jerome K. Grudem, Jr. ,  Scott A. Olson ,  Steven S. Hackett ,  Thomas V. Ressemann ,  Joel D. Phillips ,  Mark R. Christianson ,  Dennis W. Wahr

IPC分类号： A61B17/08

CPC分类号： A61B17/0469 ,  A61B17/00491 ,  A61B17/0057 ,  A61B17/0401 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00615 ,  A61B2017/0409 ,  A61B2017/0458 ,  A61B2017/0464 ,  A61B2017/0474 ,  A61B2017/0496 ,  A61B2017/22051

摘要： Devices and methods for sealing a passageway formed by a patent foramen ovale (PFO track) in the heart are provided. One method includes providing an abrading device to the PFO track and abrading the tissue within the PFO track. The abraded tissue forming the PFO track is then held together under pressure, either via lowering right atrial pressure or via applying suction to the septum primum to pull it into apposition against the septum secundum. After a sufficient period of time, the pressure is released and the abraded tissue heals to form a robust seal over the PFO track. Additionally, several devices are provided which can be placed into the PFO track to apply adhesive to the walls of the PFO track. The devices may or may not be left within the PFO track. If the devices are not left within the PFO track, the walls of the PFO track, covered with adhesive, are brought into apposition with one another and adhered together. If the device is left within the PFO track, the device is flattened from an expanded configuration to a flattened configuration, and the walls of the PFO track, adhering to the outer surface of the device, are pulled toward each other as the device flattens. The device may also include interior structure to hold the device in a flattened configuration.

摘要翻译： 提供用于密封由心脏中的卵圆孔卵孔（PFO轨迹）形成的通道的装置和方法。 一种方法包括向PFO轨道提供研磨装置并研磨PFO轨道内的组织。 形成PFO轨道的磨损组织然后在压力下保持在一起，或者通过降低右心房压力或通过向隔膜施加抽吸使其与隔膜隔层相对。 经过足够的时间后，释放压力，磨损的组织愈合，在PFO轨迹上形成牢固的密封。 另外，提供了可以放置到PFO轨道中以将粘合剂施加到PFO轨道的壁上的几个装置。 设备可能会留在PFO轨道中，也可能不会留在PFO轨道中。 如果设备不在PFO轨道内，PFO轨道的墙壁被粘合剂覆盖，彼此并置并粘合在一起。 如果设备留在PFO轨道内，则设备将从扩展配置平坦化到平坦的配置，并且随着设备平坦化，PFO轨道的粘附在设备外表面上的墙壁会相互拉紧。 该装置还可以包括用于将装置保持在扁平结构中的内部结构。

公开(公告)号：US20100234881A1

公开(公告)日：2010-09-16

申请号：US12725886

申请日：2010-03-17

申请人： David J. Blaeser ,  Peter T. Keith ,  Jerome K. Grudem, JR. ,  Scott A. Olson ,  Steven S. Hackett ,  Thomas V. Ressemann ,  Joel D. Phillips ,  Mark R. Christianson ,  Dennis W. Wahr

发明人： David J. Blaeser ,  Peter T. Keith ,  Jerome K. Grudem, JR. ,  Scott A. Olson ,  Steven S. Hackett ,  Thomas V. Ressemann ,  Joel D. Phillips ,  Mark R. Christianson ,  Dennis W. Wahr

IPC分类号： A61B17/03

CPC分类号： A61B17/0469 ,  A61B17/00491 ,  A61B17/0057 ,  A61B17/0401 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00615 ,  A61B2017/0409 ,  A61B2017/0458 ,  A61B2017/0464 ,  A61B2017/0474 ,  A61B2017/0496 ,  A61B2017/22051

摘要： Devices and methods for sealing a passageway formed by a patent foramen ovale (PFO track) in the heart are provided. One method includes providing an abrading device to the PFO track and abrading the tissue within the PFO track. The abraded tissue forming the PFO track is then held together under pressure, either via lowering right atrial pressure or via applying suction to the septum primum to pull it into apposition against the septum secundum. After a sufficient period of time, the pressure is released and the abraded tissue heals to form a robust seal over the PFO track. Additionally, several devices are provided which can be placed into the PFO track to apply adhesive to the walls of the PFO track. The devices may or may not be left within the PFO track. If the devices are not left within the PFO track, the walls of the PFO track, covered with adhesive, are brought into apposition with one another and adhered together. If the device is left within the PFO track, the device is flattened from an expanded configuration to a flattened configuration, and the walls of the PFO track, adhering to the outer surface of the device, are pulled toward each other as the device flattens. The device may also include interior structure to hold the device in a flattened configuration.

摘要翻译： 提供用于密封由心脏中的卵圆孔卵孔（PFO轨迹）形成的通道的装置和方法。 一种方法包括向PFO轨道提供研磨装置并研磨PFO轨道内的组织。 形成PFO轨道的磨损组织然后在压力下保持在一起，或者通过降低右心房压力或通过向隔膜施加抽吸使其与隔膜隔层相对。 经过足够的时间后，释放压力，磨损的组织愈合，在PFO轨迹上形成牢固的密封。 另外，提供了可以放置到PFO轨道中以将粘合剂施加到PFO轨道的壁上的几个装置。 设备可能会留在PFO轨道中，也可能不会留在PFO轨道中。 如果设备不在PFO轨道内，PFO轨道的墙壁被粘合剂覆盖，彼此并置并粘合在一起。 如果设备留在PFO轨道内，则设备将从扩展配置平坦化到平坦的配置，并且随着设备平坦化，PFO轨道的粘附在设备外表面上的墙壁会相互拉紧。 该装置还可以包括用于将装置保持在扁平结构中的内部结构。

公开(公告)号：US07691128B2

公开(公告)日：2010-04-06

申请号：US11249317

申请日：2005-10-14

申请人： David J. Blaeser ,  Peter T. Keith ,  Jerome K. Grudem, Jr. ,  Scott A. Olson ,  Steven S. Hackett ,  Thomas V. Ressemann ,  Joel D. Phillips ,  Mark R. Christianson ,  Dennis W. Wahr

发明人： David J. Blaeser ,  Peter T. Keith ,  Jerome K. Grudem, Jr. ,  Scott A. Olson ,  Steven S. Hackett ,  Thomas V. Ressemann ,  Joel D. Phillips ,  Mark R. Christianson ,  Dennis W. Wahr

IPC分类号： A61B17/08 ,  A61D1/00

CPC分类号： A61B17/0469 ,  A61B17/00491 ,  A61B17/0057 ,  A61B17/0401 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00615 ,  A61B2017/0409 ,  A61B2017/0458 ,  A61B2017/0464 ,  A61B2017/0474 ,  A61B2017/0496 ,  A61B2017/22051

摘要： Devices and methods for sealing a passageway formed by a patent foramen ovale (PFO track) in the heart are provided. One method includes providing an abrading device to the PFO track and abrading the tissue within the PFO track. The abraded tissue forming the PFO track is then held together under pressure, either via lowering right atrial pressure or via applying suction to the septum primum to pull it into apposition against the septum secundum. After a sufficient period of time, the pressure is released and the abraded tissue heals to form a robust seal over the PFO track. Additionally, several devices are provided which can be placed into the PFO track to apply adhesive to the walls of the PFO track. The devices may or may not be left within the PFO track. If the devices are not left within the PFO track, the walls of the PFO track, covered with adhesive, are brought into apposition with one another and adhered together. If the device is left within the PFO track, the device is flattened from an expanded configuration to a flattened configuration, and the walls of the PFO track, adhering to the outer surface of the device, are pulled toward each other as the device flattens. The device may also include interior structure to hold the device in a flattened configuration.

摘要翻译： 提供用于密封由心脏中的卵圆孔卵孔（PFO轨迹）形成的通道的装置和方法。 一种方法包括向PFO轨道提供研磨装置并研磨PFO轨道内的组织。 形成PFO轨道的磨损组织然后在压力下保持在一起，或者通过降低右心房压力或通过向隔膜施加抽吸使其与隔膜隔层相对。 经过足够的时间后，释放压力，磨损的组织愈合，在PFO轨迹上形成牢固的密封。 另外，提供了可以放置到PFO轨道中以将粘合剂施加到PFO轨道的壁上的几个装置。 设备可能会留在PFO轨道中，也可能不会留在PFO轨道中。 如果设备不在PFO轨道内，PFO轨道的墙壁被粘合剂覆盖，彼此并置并粘合在一起。 如果设备留在PFO轨道内，则设备将从扩展配置平坦化到平坦的配置，并且随着设备平坦化，PFO轨道的粘附在设备外表面上的墙壁会相互拉紧。 该装置还可以包括用于将装置保持在扁平结构中的内部结构。

公开(公告)号：US20120265235A1

公开(公告)日：2012-10-18

申请号：US13532351

申请日：2012-06-25

申请人： Steven S. Hackett ,  Eric S. Stainbrook ,  Thomas F. Janecek ,  Chad W. Trembath ,  Andrew J. Dusbabek ,  John R. Drontle ,  Joel D. Phillips ,  Thomas V. Ressemann ,  Kyle L. Thunstrom ,  Peter T. Keith

发明人： Steven S. Hackett ,  Eric S. Stainbrook ,  Thomas F. Janecek ,  Chad W. Trembath ,  Andrew J. Dusbabek ,  John R. Drontle ,  Joel D. Phillips ,  Thomas V. Ressemann ,  Kyle L. Thunstrom ,  Peter T. Keith

IPC分类号： A61M29/00

CPC分类号： A61B17/22032 ,  A61M25/005 ,  A61M25/10181 ,  A61M2025/0034 ,  A61M2025/0037 ,  A61M2205/8225

摘要： An evacuation sheath assembly and method of reducing or removing a blockage within a vessel without permitting embolization of particulate matter is provided. The evacuation sheath assembly includes a first elongate tubular member, having proximal and distal ends and a main lumen configured to be placed in fluid communication with a blood vessel. An expandable member is provided on a distal portion of the tubular member. The evacuation assembly further includes a second elongate tubular member having an inflation lumen configured to be placed in fluid communication with the expandable member and a gas inflator. The gas inflator is configured to be placed in fluid communication with the inflation lumen in order to provide a regulated pressure gas source for inflating the expandable member.

摘要翻译： 提供疏散护套组件以及在不允许颗粒物质栓塞的情况下减少或去除容器内的堵塞的方法。 抽真空组件包括第一细长管状构件，其具有近端和远端以及构造成与血管流体连通的主腔。 可膨胀构件设置在管状构件的远侧部分上。 排气组件还包括具有构造成与可膨胀构件和气体充气器流体连通的膨胀腔的第二细长管状构件。 气体充气机构造成与膨胀腔流体连通，以便提供用于使可膨胀构件膨胀的调节压力气体源。