公开(公告)号：US20110054298A1

公开(公告)日：2011-03-03

申请号：US12933037

申请日：2009-03-18

申请人： Jakob J. Stamnes ,  Knut Stamnes ,  Lu Zhao ,  Boerge Hamre ,  Gennady Ryzhikov ,  Marina Biryulina ,  Endre R. Sommersten ,  Kristian Pagh Nielsen ,  Johan E. Moan

发明人： Jakob J. Stamnes ,  Knut Stamnes ,  Lu Zhao ,  Boerge Hamre ,  Gennady Ryzhikov ,  Marina Biryulina ,  Endre R. Sommersten ,  Kristian Pagh Nielsen ,  Johan E. Moan

IPC分类号： A61B6/00 ,  G06K9/00

CPC分类号： G01N21/4738 ,  A61B5/0059 ,  A61B5/1455 ,  A61B5/444 ,  G06K9/00134 ,  G06T7/62 ,  G06T7/66 ,  G06T2207/30024

摘要： In an embodiment of the present disclosure, an optical method for determining morphological parameters and physiological properties of tissue is presented. The method includes using reflectance measurements from a tissue area for a plurality of wavelengths, using a bio-optical model, using radiative transfer modeling and using a non-linear inversion procedure. The method further includes systematically varying values of the morphological parameters and physiological properties of the tissue and simultaneously varying the inherent optical properties, which are linked to the morphological parameters and the physiological properties of the tissue, until the non-linear inversion procedure returns values for the morphological parameters and the physiological properties of the tissue such that an agreement between the reflectance measurements and reflectances computed by the radiative transfer model, based on the returned morphological parameters and the physiological properties of the tissue values and corresponding inherent optical properties values, reach a predetermined level of accuracy.

摘要翻译： 在本公开的实施例中，提出了用于确定组织的形态参数和生理特性的光学方法。 该方法包括使用生物光学模型，使用辐射传递建模和使用非线性反演程序，从组织区域对多个波长使用反射率测量。 该方法还包括系统地改变组织的形态学参数和生理特性的值，并且同时改变固有的光学性质，其与组织的形态参数和生理特性相关，直到非线性反演程序返回值为 基于返回的形态参数和组织值的生理特性和相应的固有光学性质值，通过辐射传递模型计算的反射率测量值和反射率之间的一致性达到了 预先确定的准确度。

公开(公告)号：US09823189B2

公开(公告)日：2017-11-21

申请号：US12933037

申请日：2009-03-18

申请人： Jakob J. Stamnes ,  Knut Stamnes ,  Lu Zhao ,  Boerge Hamre ,  Gennady Ryzhikov ,  Marina Biryulina ,  Endre R. Sommersten ,  Kristian Pagh Nielsen ,  Johan E. Moan

发明人： Jakob J. Stamnes ,  Knut Stamnes ,  Lu Zhao ,  Boerge Hamre ,  Gennady Ryzhikov ,  Marina Biryulina ,  Endre R. Sommersten ,  Kristian Pagh Nielsen ,  Johan E. Moan

IPC分类号： A61B6/00 ,  G01N21/47 ,  A61B5/00 ,  A61B5/1455 ,  G06K9/00 ,  G06T7/62 ,  G06T7/66

CPC分类号： G01N21/4738 ,  A61B5/0059 ,  A61B5/1455 ,  A61B5/444 ,  G06K9/00134 ,  G06T7/62 ,  G06T7/66 ,  G06T2207/30024

摘要： In an embodiment of the present disclosure, an optical method for determining morphological parameters and physiological properties of tissue is presented. The method includes using reflectance measurements from a tissue area for a plurality of wavelengths, using a bio-optical model, using radiative transfer modeling and using a non-linear inversion procedure. The method further includes systematically varying values of the morphological parameters and physiological properties of the tissue and simultaneously varying the inherent optical properties, which are linked to the morphological parameters and the physiological properties of the tissue, until the non-linear inversion procedure returns values for the morphological parameters and the physiological properties of the tissue such that an agreement between the reflectance measurements and reflectances computed by the radiative transfer model, based on the returned morphological parameters and the physiological properties of the tissue values and corresponding inherent optical properties values, reach a predetermined level of accuracy.