-
公开(公告)号：US4962047A
公开(公告)日：1990-10-09
申请号：US924033
申请日：1986-10-28
申请人： John F. Place
发明人： John F. Place
IPC分类号： C12N11/00 , G01N33/537 , G01N33/543 , G01N33/544
CPC分类号： G01N33/5375 , G01N33/54313 , Y10S435/803 , Y10S435/814 , Y10S436/824 , Y10S530/81
摘要： Gas containing granules of a resiliently compressible material having a density variable with pressure are used as a solid phase support in liquid phase reactions such in immunological reactions. Varying pressure causes the density of the granules to change and is used for mixing and separating the granules in liquid phase. In an immunological reaction, the granules having an attached antibody are combined with a solution containing an antigen, then varying pressure is applied to the solution to mix the granules in the solution to fix the antigen to the antibody and then pressure on the solution is varied to force the granules to the top or bottom of the solution whereby the solution can be separated from the granules.
摘要翻译： 使用具有密度随压力变化变化的可弹性压缩材料的含气颗粒作为液相反应中的固相载体，如免疫反应。 变化的压力导致颗粒的密度改变，并用于混合和分离液相中的颗粒。 在免疫反应中，将具有附着抗体的颗粒与含有抗原的溶液合并，然后对溶液施加变化的压力以将颗粒混合在溶液中以将抗原固定在抗体上，然后对溶液施加压力变化 以迫使颗粒到溶液的顶部或底部，从而使溶液与颗粒分离。
-
2.发明授权
公开(公告)号：US4608344A
公开(公告)日：1986-08-26
申请号：US499164
申请日：1983-05-18
申请人： Timothy J. N. Carter , Claus Dahne , John F. Place
发明人： Timothy J. N. Carter , Claus Dahne , John F. Place
IPC分类号： G01N21/64 , G01N21/27 , G01N21/77 , G01N33/543 , G01N33/553 , G01N33/48
CPC分类号： G01N21/648 , G01N21/6452 , G01N21/7703 , G01N33/553 , Y10S436/805
摘要： An analyte in solution is made to react with a spectific reactant coated on the wave-guide thus modifying the optical properties thereof. The index of refraction of the wave-guide material is higher than that of the reaction medium which ensures that a light signal injected into said guide be carried by multiple total reflection, the distance of penetration of the evanescent wave associated with the totally reflected signal being of the same order of magnitude or greater than the thickness of the analyte-reactant product layer.
摘要翻译： PCT No.PCT / EP82 / 00195 Sec。 371日期1983年5月18日 102（e）日期1983年5月18日PCT提交1982年9月8日PCT公布。 出版物WO83 / 01112 PCT 日期为1983年3月31日。使溶液中的分析物与涂覆在波导上的光谱反应物反应，从而改变其光学性质。 波导材料的折射率高于反应介质的折射率，其确保注入到导向器中的光信号通过多次全反射承载，与全反射信号相关联的ev逝波的穿透距离为 具有相同数量级或大于分析物 - 反应物产物层的厚度。
-
3.发明授权Apparatus for casting thin layer gel media in a mould and subsequently using gel for electrophoretic separation without removing it from the mould 失效用于在模具中铸造薄层凝胶介质并随后使用凝胶进行电泳分离而不将其从模具中取出的装置
公开(公告)号：US4810183A
公开(公告)日：1989-03-07
申请号：US119041
申请日：1987-11-10
申请人： John F. Place , Andre Bregnard
发明人： John F. Place , Andre Bregnard
CPC分类号： G01N27/44704 , B29C37/006 , B29C39/08 , B29K2033/00 , B29K2105/0002 , B29K2105/0061 , B29L2031/755
摘要： A mould for the casting of thin, cross-linked, polymerized resin films is subjected, when being filled with the liquid to be polymerized, to a centrifugal force field exceeding that of the earth gravitation field, the whole being for equalizing the intimate structure of the polymer and to expel therefrom the bubbles of gas possibly present therein. After curing the gel, a mixture of compounds to be separated by the application of an electric field is introduced into the gel and the latter is subjected to electrophoresis within the mould itself.
-
4.发明授权Analytical assembly usable in apparatuses for optically determining species in solution 失效可用于光学确定溶液中物质的装置中的分析组合物
公开(公告)号：US4668636A
公开(公告)日：1987-05-26
申请号：US793345
申请日：1985-10-31
IPC分类号： G01N21/03 , G01N21/77 , G01N21/75 , G01N33/552
CPC分类号： G01N21/7703 , G01N21/03 , G01N2021/0325 , G01N2201/04 , Y10S436/805 , Y10S436/807 , Y10S436/81
摘要： An apparatus responsive to optical changes in a waveguide when the latter is contacted with an analyte capable of reacting with a specific reactant thereto attached to the surface of said guide involves, for containing the analyte, an interchangeable round bottomed cuvette temporarily held by a suitably shaped carrier in working relationship with the optical components of the apparatus, this arrangement ensuring a correct optical orientation thereof relative to said component whatever the exact positioning of the cuvette.
摘要翻译： 当波导中的光学变化与能够与附着在所述导向件的表面上的特定反应物反应的分析物接触时，波导中的光学变化的装置包括用于容纳分析物的可互换的圆底比色皿，其被暂时保持在适当形状 载体与设备的光学部件处于工作关系，这种布置确保了相对于所述部件的正确的光学取向，无论比色杯的确切位置如何。
-
5.再颁专利
公开(公告)号：USRE33064E
公开(公告)日：1989-09-19
申请号：US107763
申请日：1987-10-09
申请人： Timothy J. N. Carter , Claus Dahne , John F. Place
发明人： Timothy J. N. Carter , Claus Dahne , John F. Place
IPC分类号： G01N21/77 , G01N33/543
CPC分类号： G01N33/54373 , G01N21/7703
摘要： An analyte in solution is made to react with a specific reactant coated on the wave-guide thus modifying the optical properties thereof. The index of refraction of the wave-guide material is higher than that of the reaction medium which ensures that a light signal injected into said guide be carried by multiple total reflection, the distance of penetration of the evanescent wave associated with the totally reflected signal being of the same order of magnitude or greater than the thickness of the analyte-reactant product layer.
-
6.发明授权Process for moulding gels usable for thin layers electrophoresis and use thereof 失效用于成型可用于薄层电泳的凝胶的方法及其用途
公开(公告)号：US4652354A
公开(公告)日：1987-03-24
申请号：US656462
申请日：1984-10-01
申请人： John F. Place , Andre Bregnard
发明人： John F. Place , Andre Bregnard
CPC分类号： G01N27/44704 , B29C37/006 , B29C39/08 , B29K2033/00 , B29K2105/0002 , B29K2105/0061 , B29L2031/755
摘要： A mould for the moulding by casting of thin, cross-linked, polymerized resin films is used which is subjected, when being filled with the liquid to be polymerized, to a centrifugal force field exceeding that of the earth gravitation field, the whole being for equalizing the intimate structure of the polymer and to expel therefrom the bubbles of gas possibly present therein.
摘要翻译： 使用通过铸造薄的，交联的聚合树脂膜来模塑的模具，当被充满待聚合的液体时，其被迫超过地球引力场的离心力场，整体用于 均衡聚合物的紧密结构并从其中排出可能存在于其中的气泡。
-
-
-
-
-
搜索结果
6 条记录 (耗时 0.016 秒)
