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公开(公告)号:US20050102910A1
公开(公告)日:2005-05-19
申请号:US10971634
申请日:2004-10-22
申请人: John Zych
发明人: John Zych
CPC分类号: E04D13/08 , E04D2013/0813
摘要: Drain products/systems and methods for installation are provided for diverting water away from a structure, e.g., a home's foundation. The drain products/systems are designed for use with conventional gutter and downspout systems and are adapted for installation/use at ground level. The disclosed drain products/systems are defined by a base and a side wall that surrounds the base on three sides thereof. The side wall which surrounds the base is typically defined by an inner wall portion, a bridging portion and an outer wall portion. The outer wall portion is advantageously of greater height than the inner wall portion. The difference in height between the outer wall portion and the inner wall portion typically defines a downwardly extending U-shaped portion. The disclosed drain products/systems offer superior flexibility to homeowners and/or contractors/builders, permitting efficient and reliable installation and use in countless terrains and environmental circumstances.
摘要翻译: 排水产品/系统和安装方法被提供用于将水转移到例如家庭基础的结构上。 排水产品/系统设计用于常规沟槽和降水管道系统,适用于地面安装/使用。 所公开的排水产品/系统由在其三侧围绕基座的基部和侧壁限定。 围绕基座的侧壁通常由内壁部分,桥接部分和外壁部分限定。 外壁部分有利地比内壁部分具有更大的高度。 外壁部分和内壁部分之间的高度差异通常限定向下延伸的U形部分。 公开的排水产品/系统为房主和/或承包商/建筑商提供了极高的灵活性,允许在无数地形和环境环境中高效可靠地安装和使用。
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公开(公告)号:US08232274B2
公开(公告)日:2012-07-31
申请号:US12046755
申请日:2008-03-12
申请人: Pauline C. Ting , Robert G. Aslanian , Jianhua Cao , David Won-Shik Kim , Rongze Kuang , Gang Zhou , Robert Jason Herr , Andrew John Zych , Jinhai Yang , Heping Wu , Nicolas Zorn
发明人: Pauline C. Ting , Robert G. Aslanian , Jianhua Cao , David Won-Shik Kim , Rongze Kuang , Gang Zhou , Robert Jason Herr , Andrew John Zych , Jinhai Yang , Heping Wu , Nicolas Zorn
IPC分类号: A61K31/501 , A61K31/5377 , C07D401/14 , C07D403/04 , C07D403/14 , C07D409/14 , C07D413/14 , A61P31/00
CPC分类号: C07D401/14 , C07D403/04 , C07D403/14 , C07D407/14 , C07D409/14 , C07D413/14 , C07D487/08 , C07D515/22
摘要: Disclosed is a set of compounds useful as glucan synthase inhibitors having the generic structure of Formula I: wherein the various moieties A, D, R6, etc., are as defined in the specification. These compounds are useful in treating or preventing fungal infections in a patient.
摘要翻译: 公开了一组可用作具有式I的通式结构的葡聚糖合酶抑制剂的化合物:其中各个部分A,D,R 6等如说明书中所定义。 这些化合物可用于治疗或预防患者的真菌感染。
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公开(公告)号:US20090170861A1
公开(公告)日:2009-07-02
申请号:US12046755
申请日:2008-03-12
申请人: Pauline C. Ting , Robert G. Aslanian , Jianhua Cao , David Won-Shik Kim , Rongze Kuang , Gang Zhou , Robert Jason Herr , Andrew John Zych , Jinhai Yang , Heping Wu , Nicolas Zorn
发明人: Pauline C. Ting , Robert G. Aslanian , Jianhua Cao , David Won-Shik Kim , Rongze Kuang , Gang Zhou , Robert Jason Herr , Andrew John Zych , Jinhai Yang , Heping Wu , Nicolas Zorn
IPC分类号: A61K31/501 , C07D403/04 , A01N43/58 , A01P3/00 , A61P31/10
CPC分类号: C07D401/14 , C07D403/04 , C07D403/14 , C07D407/14 , C07D409/14 , C07D413/14 , C07D487/08 , C07D515/22
摘要: In its many embodiments, the present invention provides -substituted pyridazinone compounds as glucan synthase inhibitors, methods of preparing such compounds, pharmaceutical including one or more of such compounds, methods of preparing pharmaceutical formulations including one or more such compounds or one or more such compounds along with other antifungal agents, and methods of treatment, prevention, inhibition, or amelioration of one or more fungal infections associated with glucan synthase using such compounds or pharmaceutical compositions.
摘要翻译: 在其许多实施方案中,本发明提供了作为葡聚糖合酶抑制剂的取代的哒嗪酮化合物,制备这些化合物的方法,包括一种或多种这些化合物的药物,制备药物制剂的方法,包括一种或多种这样的化合物或一种或多种这样的化合物 以及其他抗真菌剂,以及使用这些化合物或药物组合物治疗,预防,抑制或改善与葡聚糖合酶相关的一种或多种真菌感染的方法。
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