公开(公告)号：US07745438B2

公开(公告)日：2010-06-29

申请号：US11574989

申请日：2005-09-20

Applicant: Howard Barff Broughton ,  Robert Dean Dally ,  Timothy Barrett Durham ,  Maria Rosario Gonzalez-Garcia ,  Patric James Hahn ,  Kenneth James Henry, Jr. ,  Todd Jonathan Kohn ,  James Ray McCarthy ,  Timothy Alan Shepherd ,  Jon Andre Erickson ,  Ana Belen Bueno Melendo

Inventor： Howard Barff Broughton ,  Robert Dean Dally ,  Timothy Barrett Durham ,  Maria Rosario Gonzalez-Garcia ,  Patric James Hahn ,  Kenneth James Henry, Jr. ,  Todd Jonathan Kohn ,  James Ray McCarthy ,  Timothy Alan Shepherd ,  Jon Andre Erickson ,  Ana Belen Bueno Melendo

IPC: C07D265/32 ,  A61K31/5377

CPC classification number: C07C271/20 ,  C07C233/36 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2601/18 ,  C07C2603/74 ,  C07D265/30 ,  C07D265/32 ,  C07D413/12 ,  C07F7/1804

Abstract: The present invention provides BACE inhibitors of Formula (I); methods for their use and preparation, and intermediates useful for their preparation.

Abstract translation: 本发明提供式（I）的BACE抑制剂; 使用和制备方法，以及可用于制备的中间体。