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1.3-(2-acylamino-1-hydroxyethyl)-morpholine derivatives and their use as bace inhibitors 有权
标题翻译: 3-(2-酰基氨基-1-羟乙基) - 吗啉衍生物及其作为抑制剂的用途公开(公告)号:US07745438B2
公开(公告)日:2010-06-29
申请号:US11574989
申请日:2005-09-20
申请人: Howard Barff Broughton , Robert Dean Dally , Timothy Barrett Durham , Maria Rosario Gonzalez-Garcia , Patric James Hahn , Kenneth James Henry, Jr. , Todd Jonathan Kohn , James Ray McCarthy , Timothy Alan Shepherd , Jon Andre Erickson , Ana Belen Bueno Melendo
发明人: Howard Barff Broughton , Robert Dean Dally , Timothy Barrett Durham , Maria Rosario Gonzalez-Garcia , Patric James Hahn , Kenneth James Henry, Jr. , Todd Jonathan Kohn , James Ray McCarthy , Timothy Alan Shepherd , Jon Andre Erickson , Ana Belen Bueno Melendo
IPC分类号: C07D265/32 , A61K31/5377
CPC分类号: C07C271/20 , C07C233/36 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2603/74 , C07D265/30 , C07D265/32 , C07D413/12 , C07F7/1804
摘要: The present invention provides BACE inhibitors of Formula (I); methods for their use and preparation, and intermediates useful for their preparation.
摘要翻译: 本发明提供式(I)的BACE抑制剂; 使用和制备方法,以及可用于制备的中间体。