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    Intranasal compositions
    3.
    发明申请
    Intranasal compositions 有权
    鼻内成分

    公开(公告)号：US20050142073A1

    公开(公告)日：2005-06-30

    申请号：US11004556

    申请日：2004-12-03

    Applicant: Peter Watts ,  Alan Smith ,  Jonathan Castile

    Inventor： Peter Watts ,  Alan Smith ,  Jonathan Castile

    IPC: A61K9/00 ,  A61K31/435 ,  A61K47/36 ,  A61K31/46 ,  A61K9/14 ,  A61L9/04

    CPC classification number: A61K9/0043 ,  A61K31/435

    Abstract: Compositions are provided for the intranasal administration of granisetron or a pharmaceutically acceptable salt thereof. Preferred compositions are in the form of an aqueous solution. Optionally, the compositions comprise chitosan, a salt or derivative thereof or a salt of a derivative of chitosan. The compositions can be used for the treatment or prevention of nausea and/or vomiting.

    Abstract translation: 提供了用于格拉司琼或其药学上可接受的盐的鼻内给药的组合物。 优选的组合物是水溶液的形式。 任选地，组合物包含壳聚糖，其盐或衍生物或壳聚糖衍生物的盐。 该组合物可用于治疗或预防恶心和/或呕吐。

    Method of intranasal administration of granisetron
    5.
    发明授权
    Method of intranasal administration of granisetron 有权
    格拉司琼鼻内给药方法

    公开(公告)号：US07947257B2

    公开(公告)日：2011-05-24

    申请号：US11004556

    申请日：2004-12-03

    Applicant: Peter James Watts ,  Alan Smith ,  Jonathan Castile

    Inventor： Peter James Watts ,  Alan Smith ,  Jonathan Castile

    IPC: A61K9/08 ,  A61K9/12

    CPC classification number: A61K9/0043 ,  A61K31/435

    Abstract: Compositions are provided for the intranasal administration of granisetron or a pharmaceutically acceptable salt thereof. Preferred compositions are in the form of an aqueous solution. Optionally, the compositions comprise chitosan, a salt or derivative thereof or a salt of a derivative of chitosan. The compositions can be used for the treatment or prevention of nausea and/or vomiting.

    Abstract translation: 提供了用于格拉司琼或其药学上可接受的盐的鼻内给药的组合物。 优选的组合物是水溶液的形式。 任选地，组合物包含壳聚糖，其盐或衍生物或壳聚糖衍生物的盐。 该组合物可用于治疗或预防恶心和/或呕吐。

    DEVICE FOR ADMINISTERING LIQUID ANALGESICS
    6.
    发明申请
    DEVICE FOR ADMINISTERING LIQUID ANALGESICS 审中-公开
    用于管理液体药物的装置

    公开(公告)号：US20110257632A1

    公开(公告)日：2011-10-20

    申请号：US13122332

    申请日：2009-09-28

    Applicant: Jonathan Castile ,  Peter Watts ,  Alan Smith

    Inventor： Jonathan Castile ,  Peter Watts ,  Alan Smith

    IPC: A61M1/00

    CPC classification number: A61M15/08 ,  A61M15/0073

    Abstract: In the field of pain relief and treatment there is a need for a device which is able to administer several predetermined doses of an opioid analgesic in a manner which can be done simply and safely by a patient or carer; in particular in a manner which minimises the risk of administering too great a dose at any one time. A device (10), for administering a predefined number (N) of predefined volume unit doses (Vu) of an opioid analgesic in liquid form, includes a closed container (12) which contains a predetermined fill volume (Vf) of the opioid analgesic, and a dispenser (14) that is connected to the container (12). The dispenser (14) is operable to administer an individual one volume unit dose (Vu) repeatedly said predefined number of times (N). Both the dispenser (14) is adapted, and the concentration of said opioid analgesic is chosen such that said volume unit dose is in the range 0.05 to 0.15 ml.

    Abstract translation: 在疼痛缓解和治疗领域中，需要能够以可由患者或护理人员简单且安全地进行的方式施用若干预定剂量的阿片类止痛剂的装置; 特别是以任何时候最小化施用过大剂量的风险的方式。 用于施用液体形式的阿片样镇痛剂的预定数量（N）预定体积单位剂量（Vu）的装置（10）包括封闭容器（12），其包含所述阿片样镇痛药的预定填充体积（Vf） 以及连接到容器（12）的分配器（14）。 分配器（14）可操作以重复地施加单独的一个体积单位剂量（Vu）所述预定次数（N）。 适配分配器（14），并且选择所述阿片样镇痛剂的浓度使得所述体积单位剂量在0.05至0.15ml的范围内。

    Intranasal compositions
    9.
    发明申请
    Intranasal compositions 失效
    鼻内成分

    公开(公告)号：US20070140981A1

    公开(公告)日：2007-06-21

    申请号：US10596817

    申请日：2004-12-23

    Applicant: Jonathan Castile ,  Yu-Hui Cheng ,  Paul Jenkins ,  Alan Smith ,  Peter Watts

    Inventor： Jonathan Castile ,  Yu-Hui Cheng ,  Paul Jenkins ,  Alan Smith ,  Peter Watts

    IPC: A61K9/14 ,  A61K31/4745

    CPC classification number: B82Y5/00 ,  A61K9/0043 ,  A61K9/1623 ,  A61K9/1652 ,  A61K31/4184 ,  A61K47/36 ,  A61K47/40 ,  A61K47/6951 ,  Y10S514/923

    Abstract: The present invention provides compositions for the intranasal administration of zolpidem or a pharmaceutically acceptable salt thereof. Preferred compositions of the invention are in the form of aqueous solutions. Optionally the compositions of the invention comprise a cyclodextrin and/or chitosan, a salt or derivative thereof or a salt of a derivative of chitosan. The compositions can be used for the treatment or prevention insomnia or the treatment of neurological disorders such as those arising from brain trauma, stroke and spinocerebellar ataxia or in the treatment of Parkinson's disease.

    Abstract translation: 本发明提供了用于鼻内施用唑吡旦或其药学上可接受的盐的组合物。 本发明的优选组合物是水溶液的形式。 任选地，本发明的组合物包含环糊精和/或壳聚糖，其盐或衍生物或壳聚糖衍生物的盐。 该组合物可用于治疗或预防失眠或治疗诸如由脑创伤，中风和脊髓小脑共济失调引起的神经障碍或治疗帕金森病。

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