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公开(公告)号:US20100104555A1
公开(公告)日:2010-04-29
申请号:US12290017
申请日:2008-10-24
IPC分类号: A61K38/17 , A61K38/16 , C07H21/04 , C12N15/63 , C12N1/21 , C12N5/10 , C12N5/06 , C07K16/00 , A61K31/7088 , A61K39/395 , C12Q1/70 , A61P31/12
CPC分类号: A61K39/29 , A61K31/7088 , A61K39/00 , A61K39/12 , A61K2039/505 , C07K14/005 , C07K16/109 , C07K2317/21 , C07K2317/55 , C07K2317/565 , C07K2317/92 , C12N2770/24222 , C12N2770/24234
摘要: The invention relates to modified hepatitis C virus E2 polypeptides that are effective in eliciting the production of cross-neutralizing antibodies against hepatitis C virus. The invention provides modified hepatitis C virus E2 polypeptides, preparations and pharmaceutical compositions containing them, as well as methods for using these modified E2 polypeptides.
摘要翻译: 本发明涉及有效引发产生针对丙型肝炎病毒的交叉中和抗体的改良型丙型肝炎病毒E2多肽。 本发明提供了修饰的丙型肝炎病毒E2多肽,含有它们的制剂和药物组合物,以及使用这些修饰的E2多肽的方法。