公开(公告)号：US07439498B2

公开(公告)日：2008-10-21

申请号：US11260663

申请日：2005-10-28

申请人： Albert Edward Litherland ,  Jonathan P. Doupe ,  William Edward Kieser ,  Xiao-Lei Zhao ,  Gholamreza Javahery ,  Lisa Cousins ,  Ilia Tomski ,  Charles Jolliffe

发明人： Albert Edward Litherland ,  Jonathan P. Doupe ,  William Edward Kieser ,  Xiao-Lei Zhao ,  Gholamreza Javahery ,  Lisa Cousins ,  Ilia Tomski ,  Charles Jolliffe

IPC分类号： H01J49/40 ,  H01J49/28

CPC分类号： H01J49/0086 ,  B01D59/44 ,  H01J49/0077 ,  H01J49/06

摘要： This invention relates to a method and apparatus for separation of rare stable or radioactive isotopes from their atomic or molecular isobars in mass spectrometry (MS). In the present invention, the approach taken to removing atomic isobars utilizes a high transmission device for decelerating ions in combination with low energy reactions, such as ion-molecule reactions or near resonant electron transfer, in RF ion guides. The isobar is selectively depleted by electron transfer or other reactions between negative ions and gaseous targets in pressurized RF ion guides at low energies. The energy is controlled in such a way as to prevent reaction of the ion of interest while inducing reactions with the undesired isobar interference. The technique is of particular relevance to accelerator mass spectrometry (AMS) for which it allows substantial reductions in the necessary terminal voltage. The effect is to allow reductions in the size and cost of AMS installations.

摘要翻译： 本发明涉及在质谱（MS）中从其原子或分子等值线分离稀有稳定或放射性同位素的方法和装置。 在本发明中，用于除去原子等压线的方法利用高传输装置，用于在RF离子导向器中结合低能量反应（例如离子分子反应或接近谐振电子转移）来减速离子。 在低能量下，加压RF离子导向器中的等离子体被电子转移或负离子与气态靶之间的其它反应选择性地耗尽。 控制能量以防止感兴趣的离子的反应，同时诱导与不期望的等压线干涉的反应。 该技术与加速器质谱（AMS）特别相关，其能够显着降低必需的终端电压。 其效果是可以减少AMS安装的尺寸和成本。