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公开(公告)号：US20250062110A1
公开(公告)日：2025-02-20
申请号：US18721477
申请日：2022-12-14
Applicant: Thermo Fisher Scientific (Bremen) GmbH
Inventor： Nils Stöbener , Johannes Schwieters , Issaku Kohl , Leanne Verster
Abstract: Methods comprise introducing a gas sample having an ionisation potential below a first electron energy and above a second electron energy into an ion source and operating the ion source in the ON mode; measuring a signal produced by ionisation of the gas sample during a first time period; operating the ion source in the OFF mode during a second time period; determining, based on the signal measured during the first time period, an expected signal for ionisation of the gas sample during a third time period; operating the ion source in the ON mode and measuring a signal produced by ionisation of the gas sample during the third time period; calculating a deviation between the measured signal for the third time period and the expected signal for the third time period; and based on the deviation, adjusting one or more of the second set of operational parameters.
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公开(公告)号：US12189082B2
公开(公告)日：2025-01-07
申请号：US17773304
申请日：2020-10-23
Applicant: UNIVERSITETET I OSLO
Inventor： Anna Fæhn Follestad , Lasse B. N. Clausen , Jøran I. Moen , Wojciech Miloch
Abstract: A method of forecasting transport of a region of plasma density enhancement within a polar region is provided. The method comprises: providing a convection model for predicting electrostatic potential distribution within the polar region over time; determining the total electron content distribution within the polar region; and determining whether reconnection is occurring. If reconnection is determined to be occurring, the method comprises: identifying a region of plasma density enhancement using the total electron content distribution; and calculating a velocity of at least a portion of the plasma density enhancement using the convection model, such that transport of a region of plasma density enhancement over time can be forecast.
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公开(公告)号：US20240264116A1
公开(公告)日：2024-08-08
申请号：US18621600
申请日：2024-03-29
Applicant: MKS Instruments, Inc.
Inventor： Chenglong Yang , Jimmy Liu , James Edward Blessing
IPC: G01N27/623 , H01J49/28
CPC classification number: G01N27/623 , H01J49/282
Abstract: A monitoring system detects and measures a quantity of radical particles within a gas. A test chamber is coupled to a flow channel that transmits a gas. The test chamber defines an aperture connecting the test chamber and the flow channel, and the aperture permits a subset of the gas to enter the test chamber from the flow channel. An ionizer is positioned within the test chamber and generates radical ions from radical particles of the subset of the gas. A mass spectrometer measures a quantity of the radical ions, thereby providing a measurement of the radical particles in the gas.
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公开(公告)号：US11971386B2
公开(公告)日：2024-04-30
申请号：US17644704
申请日：2021-12-16
Applicant: MKS Instruments, Inc.
Inventor： Chenglong Yang , Jimmy Liu , James Edward Blessing
IPC: H01J49/28 , G01N27/623
CPC classification number: G01N27/623 , H01J49/282
Abstract: A monitoring system detects and measures a quantity of radical particles within a gas. A test chamber is coupled to a flow channel that transmits a gas. The test chamber defines an aperture connecting the test chamber and the flow channel, and the aperture permits a subset of the gas to enter the test chamber from the flow channel. An ionizer is positioned within the test chamber and generates radical ions from radical particles of the subset of the gas. A mass spectrometer measures a quantity of the radical ions, thereby providing a measurement of the radical particles in the gas.
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公开(公告)号：US20220381949A1
公开(公告)日：2022-12-01
申请号：US17773304
申请日：2020-10-23
Applicant: UNIVERSITETET I OSLO
Inventor： Anna Fæhn FOLLESTAD , Lasse B.N. CLAUSEN , Jøran I. MOEN , Wojciech MILOCH
Abstract: A method of forecasting transport of a region of plasma density enhancement within a polar region is provided. The method comprises: providing a convection model for predicting electrostatic potential distribution within the polar region over time; determining the total electron content distribution within the polar region; and determining whether reconnection is occurring. If reconnection is determined to be occurring, the method comprises: identifying a region of plasma density enhancement using the total electron content distribution; and calculating a velocity of at least a portion of the plasma density enhancement using the convection model, such that transport of a region of plasma density enhancement over time can be forecast.
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Patent Agency Ranking
公开(公告)号：US20220223401A1
公开(公告)日：2022-07-14
申请号：US17703899
申请日：2022-03-24
Applicant: Thermo Fisher Scientific (Bremen) GmbH
Inventor： Johannes Schwieters , Gerhard Jung
Abstract: An isotope ratio mass spectrometer has an ion source, a static field mass filter, a reaction cell to induce a mass shift reaction, and a sector field mass analyser for spatially separating ions from the reaction cell according to their m/z. A detector platform detects a plurality of different ion species separated by the sector field mass analyser. The static field mass filter has a first Wien filter that deflects ions away from a longitudinal symmetry axis of the spectrometer in accordance with the ions' m/z, and a second Wien filter that deflects ions back towards the longitudinal symmetry axis in accordance with the ions' m/z. An inverting lens is positioned along the longitudinal axis between the Wien filters to invert the direction of deflection of the ions from the first Wien filter. The static field mass filter provides high transmission and improved spectrometer sensitivity. The first and second Wien filters permit simple tuning.
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公开(公告)号：US11276567B2
公开(公告)日：2022-03-15
申请号：US16455837
申请日：2019-06-28
Applicant: THE UNIVERSITY OF HONG KONG
Inventor： Kwan Ming Ng , Ho Wai Tang , Sin Heng Man
Abstract: On field ionization under ambient conditions is described and applied on both ionization and desorption of various chemicals and biochemical present on the surface of materials in solid, liquid or gas states. The Atmospheric Pressure Megavolt Electrostatic Field Ionization Desorption (APME-FID) method generates ions directly from the surface of samples connected to a high electrical voltage at megavolt conditions. Megavolt electrostatic potential is generated and gradually accumulated directly on the sample surface by a Van de Graaff generator without causing damage to the sample. Therefore, when coupled with mass spectrometric system, the APME-FID-MS method enables direct detection of analytes on the surface of samples in different sizes and diverse types.
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公开(公告)号：US11049704B1
公开(公告)日：2021-06-29
申请号：US16879105
申请日：2020-05-20
Applicant: APPLIED MATERIALS ISRAEL LTD.
Inventor： Irit Ruach-Nir , Michal Eilon , Guy Eytan , Magen Yaacov Schulman , Sven Ruhle , Manuel Radek , Igor Krivts (Krayvitz)
Abstract: A cleanliness monitor, an evaluation system and a method. The cleanliness monitor may include: a first vacuum chamber, a second vacuum chamber, a molecule collector, a release unit, a mass spectrometer, a manipulator that may be configured to move the molecule collector from the first position to the second position, and an analyzer. The mass spectrometer may have a line of sight to an inner space of the second vacuum chamber. The mass spectrometer may be configured to monitor the inner space of the second vacuum chamber and to generate detection signals that are indicative of a content of the inner space of the second vacuum chamber. A first subset of the detection signals may be indicative of a presence of the at least subset of released organic molecules. The analyzer may be configured to determine, based on the detection signals, the cleanliness of at least one out of (a) the first vacuum chamber, and (b) a tested vacuum chamber. The tested vacuum chamber is fluidly coupled to the first vacuum chamber.
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公开(公告)号：US20210142994A1
公开(公告)日：2021-05-13
申请号：US17156373
申请日：2021-01-22
Applicant: Thermo Fisher Scientific (Bremen) GmbH
Inventor： Alexander KHOLOMEEV , Gregor QUIRING , Frank CZEMPER
Abstract: There is disclosed a method for eliminating an added crosstalk signal from a measured data signal, which is generated by an image current. There is further disclosed a signal processing unit for carrying out the method. There is still further disclosed a mass spectrometer and a mass analyser comprising the signal processing unit for carrying out the method. There is yet still further disclosed a Fourier transform mass spectrometer configured to eliminate the added crosstalk signal from a measured data signal.
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公开(公告)号：US10910205B2
公开(公告)日：2021-02-02
申请号：US16390195
申请日：2019-04-22
Applicant: HIGHLAND INNOVATIONS INC.
Inventor： Eung Joon Jo , Yohahn Jo
Abstract: Methods, systems, apparatuses, and/or computer programs. Mass spectrometer test data (e.g. a blood sample of a medical patient) may be associated with metadata information. The associated metadata information may be associated with the medical patient. A subset of a sample reference library may be based on the associated metadata information. The sample reference library may include a plurality of sets of mass spectrometer reference data, in accordance with embodiments. Embodiments match the mass spectrometer test data with mass spectrometer reference data of the selected subset of the sample reference library. Embodiments determine characteristic information of a source of the mass spectrometer test data (e.g. the medical patient) based on the known characteristics of the matched mass spectrometer reference data.
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