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公开(公告)号:US20120237447A1
公开(公告)日:2012-09-20
申请号:US13051083
申请日:2011-03-18
CPC分类号: A61K47/48176 , A61K9/5115 , A61K9/5138 , A61K9/5192 , A61K47/58 , A61K47/6929 , A61K49/0036 , A61K49/0054 , A61K49/0065 , A61K49/0093 , A61K49/0097 , A61K49/0423 , A61K49/1818 , B01J13/02 , B82Y5/00 , B82Y30/00 , C09B47/00 , C09B67/0005 , C09B67/0032 , C09B67/0097 , C09B68/444 , C09B68/446 , G01N33/587 , Y10T428/249953 , Y10T428/2993 , Y10T428/2998
摘要: A nanoshell is disclosed, comprising a star polymer occlusion complex comprising i) an amphiphilic unimolecular star polymer having a crosslinked core covalently linked to 6 or more independent polymer arms, and ii) a cargo material occluded in the star polymer; and a shell comprising an inorganic material in contact with a peripheral surface of the star polymer occlusion complex.
摘要翻译: 公开了纳米壳,其包含星形聚合物闭塞复合物,其包含i)具有共价连接到6个或更多个独立聚合物臂的交联核心的两亲单分子星形聚合物,和ii)封闭在星形聚合物中的货物材料; 以及包含与星形聚合物闭塞复合物的外周表面接触的无机材料的外壳。
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公开(公告)号:US20110243848A1
公开(公告)日:2011-10-06
申请号:US12750147
申请日:2010-03-30
CPC分类号: A61K49/0093 , A61K47/32 , A61K47/58 , A61K47/59 , A61K47/593 , A61K47/60 , A61K49/0036 , A61K49/0054 , A61K49/0073
摘要: A composition of matter comprising an amphiphilic star polymer, the star polymer comprising a crosslinked microgel core and 6 or more independent polymer arms covalently linked to the core, the 6 or more arms each comprising a hydrophilic polymer chain segment and a hydrophobic polymer chain segment; wherein each individual metal selected from the group consisting of beryllium, magnesium, calcium, strontium, barium, radium, aluminum, gallium, indium, thallium, germanium, tin, lead, arsenic, antimony, bismuth, tellurium, polonium, and metals of Groups 3 to 12 of the Periodic Table has a concentration in the star polymer of greater than or equal to 0 parts per million and less than or equal to 100 parts per million.
摘要翻译: 包含两亲性星形聚合物的物质组合物,所述星形聚合物包含交联的微凝胶核心和共价连接到核心上的6个或更多个独立的聚合物臂,所述6个或更多个臂各自包含亲水性聚合物链段和疏水性聚合物链段; 其中选自组中的铍,镁,钙,锶,钡,镭,铝,镓,铟,铊,锗,锡,铅,砷,锑,铋,碲,onium onium和金属中的每种单独的金属 星形聚合物中的3至12的浓度大于或等于0ppm,小于或等于100ppm。
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公开(公告)号:US08765098B2
公开(公告)日:2014-07-01
申请号:US12750147
申请日:2010-03-30
申请人: Eric Andrew Appel , James Lupton Hedrick , Victor Yee-Way Lee , Robert Dennis Miller , Joseph Sly
发明人: Eric Andrew Appel , James Lupton Hedrick , Victor Yee-Way Lee , Robert Dennis Miller , Joseph Sly
CPC分类号: A61K49/0093 , A61K47/32 , A61K47/58 , A61K47/59 , A61K47/593 , A61K47/60 , A61K49/0036 , A61K49/0054 , A61K49/0073
摘要: A composition of matter comprising an amphiphilic star polymer, the star polymer comprising a crosslinked microgel core and 6 or more independent polymer arms covalently linked to the core, the 6 or more arms each comprising a hydrophilic polymer chain segment and a hydrophobic polymer chain segment; wherein each individual metal selected from the group consisting of beryllium, magnesium, calcium, strontium, barium, radium, aluminum, gallium, indium, thallium, germanium, tin, lead, arsenic, antimony, bismuth, tellurium, polonium, and metals of Groups 3 to 12 of the Periodic Table has a concentration in the star polymer of greater than or equal to 0 parts per million and less than or equal to 100 parts per million.
摘要翻译: 包含两亲性星形聚合物的物质组合物,所述星形聚合物包含交联的微凝胶核心和共价连接到核心上的6个或更多个独立的聚合物臂,所述6个或更多个臂各自包含亲水性聚合物链段和疏水性聚合物链段; 其中选自组中的铍,镁,钙,锶,钡,镭,铝,镓,铟,铊,锗,锡,铅,砷,锑,铋,碲,onium onium和金属中的每种单独的金属 星形聚合物中的3至12的浓度大于或等于0ppm,小于或等于100ppm。
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公开(公告)号:US08945513B2
公开(公告)日:2015-02-03
申请号:US13051083
申请日:2011-03-18
IPC分类号: A61B5/055 , A61K49/00 , A61K49/04 , A61K49/18 , B82Y5/00 , A61K47/48 , B01J13/02 , C09B67/02 , C09B67/08 , C09B67/00 , C09B47/00 , A61K9/51
CPC分类号: A61K47/48176 , A61K9/5115 , A61K9/5138 , A61K9/5192 , A61K47/58 , A61K47/6929 , A61K49/0036 , A61K49/0054 , A61K49/0065 , A61K49/0093 , A61K49/0097 , A61K49/0423 , A61K49/1818 , B01J13/02 , B82Y5/00 , B82Y30/00 , C09B47/00 , C09B67/0005 , C09B67/0032 , C09B67/0097 , C09B68/444 , C09B68/446 , G01N33/587 , Y10T428/249953 , Y10T428/2993 , Y10T428/2998
摘要: A nanoshell is disclosed, comprising a star polymer occlusion complex comprising i) an amphiphilic unimolecular star polymer having a crosslinked core covalently linked to 6 or more independent polymer arms, and ii) a cargo material occluded in the star polymer; and a shell comprising an inorganic material in contact with a peripheral surface of the star polymer occlusion complex.
摘要翻译: 公开了纳米壳,其包含星形聚合物闭塞复合物,其包含i)具有共价连接到6个或更多个独立聚合物臂的交联核心的两亲单分子星形聚合物,和ii)封闭在星形聚合物中的货物材料; 以及包含与星形聚合物闭塞复合物的外周表面接触的无机材料的外壳。
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