-
公开(公告)号:US20050175630A1
公开(公告)日:2005-08-11
申请号:US11021821
申请日:2004-12-22
申请人: Eyal Raz , Joshua Fierer
发明人: Eyal Raz , Joshua Fierer
IPC分类号: A61K39/116 , A61K39/39 , A61K39/02 , A61K39/108 , A61K39/04 , A61K39/095 , A61K39/112
CPC分类号: A61K39/39 , A61K39/0208 , A61K39/0275 , A61K39/07 , A61K2039/521 , A61K2039/541 , A61K2039/542 , A61K2039/55594 , A61K2039/70 , Y02A50/47 , Y02A50/482
摘要: The present invention provides an immunogenic composition comprising lethally irradiated bacteria formulated for mucosal delivery. The present invention further provides methods of preparing a subject immunogenic composition. The present invention further provides a method of inducing an immune response in an individual to an antigen, the method generally involving administering a subject immunogenic composition to a mucosal tissue of the individual.
摘要翻译: 本发明提供一种免疫原性组合物,其包含配制用于粘膜递送的致死辐照细菌。 本发明还提供了制备受试者免疫原性组合物的方法。 本发明还提供了诱导个体对抗原的免疫应答的方法,该方法通常涉及将个体免疫原性组合物给予个体的粘膜组织。