PACAP AS A MARKER FOR CANCER
    3.
    发明申请
    PACAP AS A MARKER FOR CANCER 审中-公开
    PACAP作为癌症标记

    公开(公告)号:US20110212464A1

    公开(公告)日:2011-09-01

    申请号:US13099562

    申请日:2011-05-03

    IPC分类号: G01N33/68 C12Q1/527 C12Q1/02

    CPC分类号: G01N33/57407 G01N33/57423

    摘要: The present invention relates to a method aiding in the assessment of cancer. It discloses the use of the proapoptotic caspase adaptor protein (=PACAP) as a universal marker of different types of cancer. PACAP aids in the assessment of pulmonary or lung cancer (LC), particularly of non-small cell lung carcinoma (NSCLC), but also of other specific types of cancer. Such specific types of cancer are e.g. colon, bladder, cervix, ovary, endometrial, head and neck, breast, melanoma, pancreas, kidney, prostate, esophagus, stomach or bile duct cancer. Furthermore, the present invention especially relates to a method for assessing cancer from a liquid sample, derived from an individual by measuring PACAP in said sample. Measurement of PACAP can, e.g., be used in the early detection of cancer or in the surveillance of patients who undergo surgery.

    摘要翻译: 本发明涉及一种协助癌症评估的方法。 它公开了促凋亡半胱天冬酶衔接蛋白(= PACAP)作为不同类型癌症的通用标记物的使用。 PACAP有助于评估肺或肺癌(LC),特别是非小细胞肺癌(NSCLC),还有其他特定类型的癌症。 这些特定类型的癌症是例如。 结肠,膀胱,子宫颈,卵巢,子宫内膜,头颈部,乳腺,黑素瘤,胰腺,肾,前列腺,食道,胃或胆管癌。 此外,本发明特别涉及通过测量所述样品中的PACAP从个体得到的从液体样品中评估癌症的方法。 PACAP的测量可以例如用于癌症的早期检测或用于进行手术的患者的监视。