专利检索 ap:"Julie E. Scheffler" 第 1 页

1.

发明授权
Antagonists of human granulocyte-macrophage colony stimulating factor derived from the carboxyl terminus 失效
标题翻译：来自羧基末端的人类粒细胞 - 巨噬细胞集落刺激因子的拮抗剂

公开(公告)号：US5475087A

公开(公告)日：1995-12-12

申请号：US192310

申请日：1994-02-04

申请人： Gail F. Seelig , Julie E. Scheffler , Paul P. Trotta

发明人： Gail F. Seelig , Julie E. Scheffler , Paul P. Trotta

IPC分类号： G01N33/53 , A61K38/00 , A61K39/395 , A61P31/12 , A61P35/00 , C07K20060101 , C07K7/06 , C07K7/08 , C07K14/00 , C07K14/52 , C07K14/53 , C07K14/535 , C07K16/00 , C07K16/24 , C12N5/10 , C12N5/28 , C12N15/02 , C12P21/08 , C12R1/91 , G01N33/577 , A61K38/10

CPC分类号： C07K16/243 , C07K14/535 , A61K38/00 , C07K2317/34

摘要： Antagonists of GM-CSF are disclosed that comprise antibodies and anti-idiotypic antibodies specific for the carboxyl terminus of GM-CSF. These antagonists are useful for treating various diseases, the symptoms of which are increased by GM-CSF, and for lessening the effects of chemotherapy.

摘要翻译： 公开了GM-CSF的拮抗剂，其包含对GM-CSF的羧基末端特异的抗体和抗独特型抗体。这些拮抗剂可用于治疗各种疾病，其症状通过GM-CSF增加，并且用于减轻化学疗法的作用。