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1.
公开(公告)号:US5035995A
公开(公告)日:1991-07-30
申请号:US355196
申请日:1989-05-22
申请人: Fumiaki Taguchi , Isamu Mitsui , Kinichi Hara , Masaro Hayashi , Kunio Ezawa , Kenichi Fukunaga , Jun Kuranari
发明人: Fumiaki Taguchi , Isamu Mitsui , Kinichi Hara , Masaro Hayashi , Kunio Ezawa , Kenichi Fukunaga , Jun Kuranari
IPC分类号: A61K49/00 , A61K51/04 , A61K51/08 , G01N33/532 , G01N33/564 , G01N33/58
CPC分类号: G01N33/58 , A61K49/001 , A61K49/0043 , A61K49/0056 , A61K51/04 , A61K51/081 , G01N33/532 , G01N33/564
摘要: A substance-conjugated complement component C1q is provided. A substance such as signal emitting substances or cell function regulating substances is conjugated via a sulfur atom to at least one site of the component. The site is not involved in binding immunoglobulins. A marker-labelled complement component C1q is used for measuring a complement-binding antibody, an antigen, a neutralizing antibody or a substance produced internally of and at the surface of a cell or a microorganism by measuring the marker.
摘要翻译: 提供了一种物质共轭的补体成分C1q。 诸如信号发射物质或细胞功能调节物质的物质通过硫原子与至少一个组分的位点共轭。 该位点不涉及结合免疫球蛋白。 标记标记的补体成分C1q用于测定补体结合抗体,抗原,中和抗体或通过测定标记物在细胞或微生物的内部和表面产生的物质。
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公开(公告)号:US4882423A
公开(公告)日:1989-11-21
申请号:US32025
申请日:1987-03-30
申请人: Fumiaki Taguchi , Isamu Mitsui , Kinichi Hara , Masaro Hayashi , Kunio Ezawa , Kenichi Fukunaga , Jun Kuranari
发明人: Fumiaki Taguchi , Isamu Mitsui , Kinichi Hara , Masaro Hayashi , Kunio Ezawa , Kenichi Fukunaga , Jun Kuranari
IPC分类号: A61K49/00 , A61K51/04 , A61K51/08 , G01N33/564 , G01N33/58
CPC分类号: A61K49/0043 , A61K49/001 , A61K49/0056 , A61K51/04 , A61K51/081 , G01N33/564 , G01N33/58
摘要: A substance-conjugated complement component Clq is provided. A substance such as signal emitting substances or cell function regulating substances is conjugated via a sulfur atom to at least one site of the component. The site is not involved in binding immunoglobulins. A marker-labelled complement component Clq is used for measuring a complement-binding antibody, an antigen, a neutralizing antibody or a substance produced internally of and at the surface of a cell or a microorganism by measuring the marker.
摘要翻译: 提供了物质偶联的补体成分Clq。 诸如信号发射物质或细胞功能调节物质的物质通过硫原子与至少一个组分的位点共轭。 该位点不涉及结合免疫球蛋白。 标记标记的补体成分Clq用于测定补体结合抗体,抗原,中和抗体或通过测定标记物在细胞或微生物的内部和表面产生的物质。
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