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公开(公告)号:US07585507B2
公开(公告)日:2009-09-08
申请号:US11124786
申请日:2005-05-09
申请人: Grant McFadden , Karim Essani
发明人: Grant McFadden , Karim Essani
IPC分类号: A61K39/275 , A61K38/16
CPC分类号: C07K14/005 , A01K2217/05 , A01K2217/075 , A61K38/00 , C12N2710/24022
摘要: The invention provides gp38 polypeptides, which play a role in immunomodulation, nucleic acid molecules encoding these polypeptides, and therapeutic and diagnostic methods employing these polypeptides and nucleic acid molecules. The invention also provides methods for identifying compounds that modulate the biological activities of gp38 nucleic acid molecules and polypeptides, and therapeutic methods employing these compounds.
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公开(公告)号:US08268331B2
公开(公告)日:2012-09-18
申请号:US12437426
申请日:2009-05-07
申请人: Grant McFadden , Karim Essani
发明人: Grant McFadden , Karim Essani
IPC分类号: A61K39/12 , A61K39/275 , A61K38/00
CPC分类号: C07K14/005 , A01K2217/05 , A01K2217/075 , A61K38/00 , C12N2710/24022
摘要: The invention provides gp38 polypeptides, which play a role in immunomodulation, nucleic acid molecules encoding these polypeptides, and therapeutic and diagnostic methods employing these polypeptides and nucleic acid molecules. The invention also provides methods for identifying compounds that modulate the biological activities of gp38 nucleic acid molecules and polypeptides, and therapeutic methods employing these compounds.
摘要翻译: 本发明提供了在免疫调节中起作用的gp38多肽,编码这些多肽的核酸分子,以及使用这些多肽和核酸分子的治疗和诊断方法。 本发明还提供鉴定调节gp38核酸分子和多肽的生物学活性的化合物的方法,以及使用这些化合物的治疗方法。
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公开(公告)号:US20060286125A1
公开(公告)日:2006-12-21
申请号:US11124786
申请日:2005-05-09
申请人: Grant McFadden , Karim Essani
发明人: Grant McFadden , Karim Essani
IPC分类号: A61K48/00 , A61K39/275 , A61K39/285 , C07K14/065
CPC分类号: C07K14/005 , A01K2217/05 , A01K2217/075 , A61K38/00 , C12N2710/24022
摘要: The invention provides gp38 polypeptides, which play a role in immunomodulation, nucleic acid molecules encoding these polypeptides, and therapeutic and diagnostic methods employing these polypeptides and nucleic acid molecules. The invention also provides methods for identifying compounds that modulate the biological activities of gp38 nucleic acid molecules and polypeptides, and therapeutic methods employing these compounds.
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公开(公告)号:US20110064757A1
公开(公告)日:2011-03-17
申请号:US12437426
申请日:2009-05-07
申请人: Grant McFadden , Karim Essani
发明人: Grant McFadden , Karim Essani
IPC分类号: A61K39/275 , A61P29/00 , A61P19/02 , A61P1/00 , A61P9/00
CPC分类号: C07K14/005 , A01K2217/05 , A01K2217/075 , A61K38/00 , C12N2710/24022
摘要: The invention provides gp38 polypeptides, which play a role in immunomodulation, nucleic acid molecules encoding these polypeptides, and therapeutic and diagnostic methods employing these polypeptides and nucleic acid molecules. The invention also provides methods for identifying compounds that modulate the biological activities of gp38 nucleic acid molecules and polypeptides, and therapeutic methods employing these compounds.
摘要翻译: 本发明提供了在免疫调节中起作用的gp38多肽,编码这些多肽的核酸分子,以及使用这些多肽和核酸分子的治疗和诊断方法。 本发明还提供鉴定调节gp38核酸分子和多肽的生物学活性的化合物的方法,以及使用这些化合物的治疗方法。
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公开(公告)号:US06894155B2
公开(公告)日:2005-05-17
申请号:US09976605
申请日:2001-10-11
申请人: Grant McFadden , Karim Essani
发明人: Grant McFadden , Karim Essani
IPC分类号: A01K67/027 , A61K38/00 , A61K39/275 , A61P1/04 , A61P1/16 , A61P3/10 , A61P5/16 , A61P7/00 , A61P7/06 , A61P7/08 , A61P9/10 , A61P11/00 , A61P11/02 , A61P11/06 , A61P13/12 , A61P15/06 , A61P17/00 , A61P17/02 , A61P17/06 , A61P19/00 , A61P21/02 , A61P21/04 , A61P25/00 , A61P25/28 , A61P29/00 , A61P31/12 , A61P31/18 , A61P35/02 , A61P37/02 , A61P37/04 , A61P37/06 , A61P37/08 , A61P43/00 , C07K14/065 , C07K16/08 , C12N5/10 , C12N15/09 , C12Q1/02 , C12Q1/68 , G01N33/15 , G01N33/50 , G01N33/53 , G01N33/566 , G01N33/569 , C07H21/04
CPC分类号: C07K14/005 , A01K2217/05 , A01K2217/075 , A61K38/00 , C12N2710/24022
摘要: The invention provides gp38 polypeptides, which play a role in immunomodulation, nucleic acid molecules encoding these polypeptides, and therapeutic and diagnostic methods employing these polypeptides and nucleic acid molecules. The invention also provides methods for identifying compounds that modulate the biological activities of gp38 nucleic acid molecules and polypeptides, and therapeutic methods employing these compounds.
摘要翻译: 本发明提供了在免疫调节中起作用的gp38多肽,编码这些多肽的核酸分子,以及使用这些多肽和核酸分子的治疗和诊断方法。 本发明还提供鉴定调节gp38核酸分子和多肽的生物学活性的化合物的方法,以及使用这些化合物的治疗方法。
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