公开(公告)号：US20190039071A1

公开(公告)日：2019-02-07

申请号：US16105283

申请日：2018-08-20

申请人： Brandeis University ,  President and Fellows of Harvard College

发明人： Seth Fraden ,  Hakim Boukellal ,  Yanwei Jia ,  Seila Selimovic ,  Amy Rowat ,  Jeremy Agresti ,  David A. Weitz

IPC分类号： B01L3/00 ,  F17D1/12 ,  G01N1/28 ,  G01N15/02 ,  G01N15/14 ,  G01N15/00

CPC分类号： B01L3/502784 ,  B01L3/502746 ,  B01L2200/0673 ,  B01L2300/0861 ,  B01L2300/087 ,  B01L2300/0877 ,  B01L2400/0487 ,  B01L2400/0688 ,  B01L2400/0694 ,  B01L2400/082 ,  F17D1/12 ,  G01N1/28 ,  G01N15/0272 ,  G01N15/1484 ,  G01N2015/0092 ,  Y10T137/0324 ,  Y10T137/0391 ,  Y10T137/0396 ,  Y10T137/2082 ,  Y10T137/218 ,  Y10T436/2575

摘要： Microfluidic structures and methods for manipulating fluids, fluid components, and reactions are provided. In one aspect, such structures and methods can allow production of droplets of a precise volume, which can be stored/maintained at precise regions of the device. In another aspect, microfluidic structures and methods described herein are designed for containing and positioning components in an arrangement such that the components can be manipulated and then tracked even after manipulation. For example, cells may be constrained in an arrangement in microfluidic structures described herein to facilitate tracking during their growth and/or after they multiply.

公开(公告)号：US09987631B2

公开(公告)日：2018-06-05

申请号：US13583097

申请日：2010-08-05

申请人： Young-Ho Cho ,  Il Doh ,  Hwan-Il Yoo

发明人： Young-Ho Cho ,  Il Doh ,  Hwan-Il Yoo

IPC分类号： B01L3/00 ,  C12M1/34 ,  G01N33/487 ,  G01N1/40 ,  G01N15/02 ,  G01N15/00

CPC分类号： B01L3/502746 ,  B01L3/502753 ,  B01L2200/0668 ,  B01L2300/0816 ,  B01L2300/0877 ,  B01L2400/086 ,  G01N1/4077 ,  G01N15/0272 ,  G01N2015/0053

摘要： A particle processing device includes a chamber and at least one capturing structure. The chamber is connected to a first port and a second port to provide a space between the first and second ports for flowing of a fluid having a particle. The capturing structure is provided in the chamber to form a fluidic channel, wherein the fluidic channel has a first opening and a second opening and a capturing region is formed between the first and second openings such that the capturing region has a changeable sectional shape for capturing the particle in the fluid flowing from the first port to the second port.

公开(公告)号：US20180078939A1

公开(公告)日：2018-03-22

申请号：US15270514

申请日：2016-09-20

申请人： INTERNATIONAL BUSINESS MACHINES CORPORATION

发明人： HUAN HU ,  SUNG CHEOL KIM ,  JOSHUA T. SMITH ,  BENJAMIN H. WUNSCH

IPC分类号： B01L3/00 ,  B03B5/48

CPC分类号： B01L3/502761 ,  B01L3/502746 ,  B01L2200/0636 ,  B01L2200/0652 ,  B01L2300/0816 ,  B01L2400/086 ,  B03B5/48 ,  G01N15/0272 ,  G01N2015/0053

摘要： A deterministic lateral displacement array that includes a channel, within a substrate, having a first sidewall, a second sidewall, and a channel length. A condenser portion that includes an entry port and an exit port. A first array of pillars is disposed between the entry port and the exit port of the condenser portion along the channel length, the first array of pillars operative to drive a first material particle and a second material particle towards the first sidewall of the channel. A separator portion that includes an entry port and an exit port, and a second array of pillars disposed between the entry port and the exit port of the separator portion along the channel length, the pillars operative to drive the first material particle towards the second sidewall of the channel.

公开(公告)号：US09874509B2

公开(公告)日：2018-01-23

申请号：US14724049

申请日：2015-05-28

申请人： Ford Global Technologies, LLC

发明人： Yasser Mohamed Sayed Yacoub ,  Matthew Allen Schneider

IPC分类号： G01M15/10 ,  G01N15/06 ,  G01N15/02 ,  G01N15/08

CPC分类号： G01N15/0656 ,  G01N15/0272 ,  G01N15/08 ,  G01N2015/084

摘要： Embodiments of a particle sensor are provided. In one example, a particle sensor for an exhaust system comprises at least two inlet openings for an exhaust-gas flow of the exhaust system, wherein the inlet openings are of different sizes, and at least two sensor elements, wherein in each case one sensor element is arranged downstream of one inlet opening. In this way, the relative proportion of different-sized particles within the exhaust-gas flow may be determined.

公开(公告)号：US20170160263A1

公开(公告)日：2017-06-08

申请号：US15434249

申请日：2017-02-16

申请人： ANGLE North America, Inc.

发明人： Georgi HVICHIA

IPC分类号： G01N33/49 ,  C12N5/09 ,  B01L3/00

CPC分类号： B01L3/502753 ,  B01L2200/0652 ,  B01L2200/12 ,  B01L2300/0816 ,  B01L2300/0864 ,  C12N5/0694 ,  C12Q1/24 ,  G01N15/0272 ,  G01N33/491 ,  G01N33/574 ,  G01N2015/0288

摘要： The disclosure relates to an apparatus for segregating particles on the basis of their ability to flow through a stepped passageway. At least some of the particles are unable to pass through a narrower passageway bounded by a segregating step, resulting in segregation of the particles. The breadth of the leading edge of at least one step of the apparatus is significantly greater than the overall width of the passageway in which the step occurs, permitting high and rapid sample throughput. The apparatus and methods described herein can be used to segregate particles of a wide variety of types. By way of example, they can be used to segregate circulating tumor cells from a human blood sample.

公开(公告)号：US20170128943A1

公开(公告)日：2017-05-11

申请号：US15415156

申请日：2017-01-25

申请人： Raindance Technologies, Inc.

发明人： Seth Fraden ,  Hakim Boukellal ,  Yanwei Jia ,  Seila Selimovic ,  Amy Rowat ,  Jeremy Agresti ,  David A. Weitz

IPC分类号： B01L3/00 ,  G01N1/28 ,  G01N15/14 ,  F17D1/12 ,  G01N15/02

CPC分类号： B01L3/502784 ,  B01L3/502746 ,  B01L2200/0673 ,  B01L2300/0861 ,  B01L2300/087 ,  B01L2300/0877 ,  B01L2400/0487 ,  B01L2400/0688 ,  B01L2400/0694 ,  B01L2400/082 ,  F17D1/12 ,  G01N1/28 ,  G01N15/0272 ,  G01N15/1484 ,  G01N2015/0092 ,  Y10T137/0324 ,  Y10T137/0391 ,  Y10T137/0396 ,  Y10T137/2082 ,  Y10T137/218 ,  Y10T436/2575

摘要： Microfluidic structures and methods for manipulating fluids, fluid components, and reactions are provided. In one aspect, such structures and methods can allow production of droplets of a precise volume, which can be stored/maintained at precise regions of the device. In another aspect, microfluidic structures and methods described herein are designed for containing and positioning components in an arrangement such that the components can be manipulated and then tracked even after manipulation. For example, cells may be constrained in an arrangement in microfluidic structures described herein to facilitate tracking during their growth and/or after they multiply.

公开(公告)号：US09616369B2

公开(公告)日：2017-04-11

申请号：US14127068

申请日：2011-08-08

申请人： Takuji Ikeda ,  Yoshio Otani ,  Masami Furuuchi ,  Takafumi Seto

发明人： Takuji Ikeda ,  Yoshio Otani ,  Masami Furuuchi ,  Takafumi Seto

IPC分类号： B01D51/00 ,  B01D46/00 ,  B01D46/24 ,  B01D46/52 ,  B01D46/10 ,  B01D45/08 ,  B01D45/04 ,  G01N1/22 ,  B01D46/12 ,  G01N15/02

CPC分类号： B01D46/0023 ,  B01D45/04 ,  B01D45/08 ,  B01D46/0002 ,  B01D46/0005 ,  B01D46/0041 ,  B01D46/10 ,  B01D46/12 ,  B01D46/2411 ,  B01D46/521 ,  G01N1/2208 ,  G01N1/2211 ,  G01N15/0255 ,  G01N15/0272

摘要： An inertial filter to be disposed in the air flow path of a stream of air containing nanoparticles includes plural particle classifying sheets having plural mesh-like holes are disposed in the air flow path. The plural particle classifying sheets are stacked on each other in a manner that a part of at least one of the particle classifying sheets overlaps with the other particle classifying sheet. The inertial filter can adjust a classification diameter by adjusting a shadow area ratio on a projection view obtained by virtually projecting the plural particle classifying sheets from a downstream side to an upstream side of the air flow path.

公开(公告)号：US09453091B2

公开(公告)日：2016-09-27

申请号：US13635045

申请日：2011-03-17

申请人： Sumio Okuda ,  Syuji Kanzaki ,  Kunihiko Ishizaki ,  Shinichi Fujino ,  Kozo Nogi

发明人： Sumio Okuda ,  Syuji Kanzaki ,  Kunihiko Ishizaki ,  Shinichi Fujino ,  Kozo Nogi

IPC分类号： A61L15/24 ,  C08F120/06 ,  C08F220/06 ,  C08J3/24 ,  B07B1/56 ,  C08F6/00 ,  B07B13/16 ,  G01N15/02 ,  B07B1/28

CPC分类号： C08F120/06 ,  B07B1/28 ,  B07B1/54 ,  B07B1/56 ,  B07B13/16 ,  C08F6/008 ,  C08F220/06 ,  C08J3/24 ,  C08J3/245 ,  C08J2300/14 ,  G01N15/0272 ,  G01N2015/0277 ,  G01N2015/0288

摘要： A method for producing a water absorbent resin, the method including a polymerization step, a drying step, a classification step, and a surface crosslinking step. The classification step carried out before or after the surface crosslinking step requires use of a metal sieve mesh having stretch tension from 35 to 100 N/cm, in which an air jet cleaner or an air jet brush cleaner and plural tapping balls or tapping blocks are installed below the metal sieve mesh, a classification aid particle having specific gravity different from that of the water absorbent resin powder is added, and a fine powder of the water absorbent resin and the classification aid particle are removed.

摘要翻译： 一种吸水性树脂的制造方法，其包括聚合工序，干燥工序，分级工序以及表面交联工序。 在表面交联步骤之前或之后进行的分级步骤需要使用具有35至100N / cm的拉伸张力的金属筛网，其中空气喷射清洁器或空气喷射刷清洁器和多个敲击球或攻丝块是 在金属筛网的下方，添加比重与吸水性树脂粉末不同的分级助剂粒子，除去吸水性树脂和分级助剂粒子的细粉末。

公开(公告)号：US20160047729A1

公开(公告)日：2016-02-18

申请号：US14872241

申请日：2015-10-01

申请人： Linda Libasci

发明人： Linda Libasci

IPC分类号： G01N15/02 ,  G01F19/00

CPC分类号： G01N15/0272 ,  G01F19/00

摘要： Disclosed is a size portable particle size distribution sampling device that is small enough to be carried by truckers and handled by terminal personnel. The device consists of multiple nesting screening (sieve) cups, with a sample cup at the top, a plurality of screening cups in sequence below the sample cup and a base container at the bottom. Methods of use are also disclosed.

摘要翻译： 公开了一种尺寸便携式粒度分布采样装置，其尺寸足够小以由卡车司机携带并由终端人员处理。 该装置由多个嵌套筛（筛）杯组成，顶部有样品杯，多个筛子杯依次位于样品杯下方，底部容器位于底部。 还公开了使用方法。

公开(公告)号：US20150147814A1

公开(公告)日：2015-05-28

申请号：US14088403

申请日：2013-11-24

申请人： Kemira

发明人： Iiris Joensuu ,  Marjatta Piironen

IPC分类号： G01N33/34

CPC分类号： G01N33/343 ,  G01N15/0255 ,  G01N15/0272 ,  G01N21/85 ,  G01N2015/0053

摘要： The invention relates to a method and system for monitoring of particles properties in a stream and the use of such method and system. In particular, the invention concerns sampling of liquids like aqueous suspensions or filtrates that contain solid matter in forest industry, oil and mining industry, as well as in and water treatment, desalination or water reuse processes, and in subsequent measurement of the samples. A sample from a stream of liquid is dyed to stain particles contained in the sample, which is conducted to a first flow chamber having means for causing said sample to be divided into particle populations according to their size or mass. A liquid flow is applied through the first flow chamber to cause at least one particle population to flow into a second flow chamber. The particle populations are measured to produce at least one measurement signal representative of the amount and/or properties of the particles, and processing extract key variables of each particle population and presenting them as an analysis of particle populations or the whole sample in terms of a count and size of particles and/or their hydrophobicity.

摘要翻译： 本发明涉及用于监测流中颗粒性质的方法和系统以及这种方法和系统的使用。 特别地，本发明涉及在森林工业，石油和采矿业以及在水处理，脱盐或水再利用过程中以及随后的样品测量中的液体如水悬浮液或滤液的采样。 来自液体流的样品被染色以染色样品中包含的颗粒，其被传导到具有根据其尺寸或质量将所述样品分成颗粒群的装置的第一流动室。 通过第一流动室施加液体流以使至少一个颗粒群流入第二流动室。 测量颗粒群以产生表示颗粒的量和/或性质的至少一个测量信号，并处理提取每个颗粒群体的关键变量，并将其作为颗粒群体或整个样品的分析，以 颗粒的数量和尺寸和/或其疏水性。