公开(公告)号：US10386371B2

公开(公告)日：2019-08-20

申请号：US14343334

申请日：2012-09-07

申请人： Benjamin P. Bowen ,  Katherine B. Louie ,  Trent R. Northen ,  Marc K. Hellerstein

发明人： Benjamin P. Bowen ,  Katherine B. Louie ,  Trent R. Northen ,  Marc K. Hellerstein

IPC分类号： G01N33/58 ,  G16B20/00 ,  G01N33/68

摘要： Provided herein are methods for measuring molecular flux rates of molecules of interest in a tissue sample in spatially-organized manner and generating output (e.g., an image, a heat map, a contour map, a table or a database) representing the molecular flux rates of each spatially-defined location of the sample. Provided herein are also the output, as well as systems and computer-readable medium with computer-executable instructions for determining molecular flux rates of molecules of interest in the sample.

公开(公告)号：US20140329274A1

公开(公告)日：2014-11-06

申请号：US14343334

申请日：2012-09-07

申请人： Benjamin P. Bowen ,  Katherine B. Louie ,  Trent R. Northen ,  Marc K. Hellerstein

发明人： Benjamin P. Bowen ,  Katherine B. Louie ,  Trent R. Northen ,  Marc K. Hellerstein

IPC分类号： G01N33/58

CPC分类号： G01N33/58 ,  G01N33/6848 ,  G01N2458/15 ,  G01N2570/00 ,  G01N2800/7028 ,  G16B20/00 ,  Y10T436/24

摘要： Provided herein are methods for measuring molecular flux rates of molecules of interest in a tissue sample in spatially-organized manner and generating output (e.g., an image, a heat map, a contour map, a table or a database) representing the molecular flux rates of each spatially-defined location of the sample. Provided herein are also the output, as well as systems and computer-readable medium with computer-executable instructions for determining molecular flux rates of molecules of interest in the sample.

摘要翻译： 本文提供了以空间有组织的方式测量组织样品中感兴趣的分子的分子通量速率并产生代表分子通量速率的输出（例如，图像，热图，轮廓图，表或数据库）的方法 的样品的每个空间定义的位置。 本文还提供了输出以及具有用于确定样品中感兴趣的分子的分子通量速率的计算机可执行指令的系统和计算机可读介质。