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1.发明授权Methods and compositions for determining the pathogenic status of infectious agents 有权用于确定感染因子的致病状态的方法和组合物公开(公告)号：US08501400B2
公开(公告)日：2013-08-06
申请号：US13011754
申请日：2011-01-21
摘要： The present invention relates to methods and compositions for improved detection of infectious agents and microbes. In particular, the present invention provides novel methods for detecting infectious agents, providing information about the viability status of such infectious agents and for determining drug susceptibility. In certain embodiments, the present invention employs techniques involving nucleic acid amplification-based microbial identification together with phage-based biological detection of drug resistance. The methods of the invention are suitable for all microbes and infectious agents, including bacterial agents such as Mycobacteria.
摘要翻译： 本发明涉及用于改善感染因子和微生物检测的方法和组合物。 特别地，本发明提供了用于检测感染因子的新方法，提供关于这种感染剂的生存状态的信息和用于确定药物敏感性。 在某些实施方案中，本发明使用涉及基于核酸扩增的微生物鉴定以及基于噬菌体的药物抗性生物检测的技术。 本发明的方法适用于所有微生物和感染因子，包括细菌剂如分枝杆菌。
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2.发明申请Methods and compositions for determining the pathogenic status of infectious agents 有权用于确定感染因子的致病状态的方法和组合物公开(公告)号：US20110212457A1
公开(公告)日：2011-09-01
申请号：US13011754
申请日：2011-01-21
摘要： The present invention relates to methods and compositions for improved detection of infectious agents and microbes. In particular, the present invention provides novel methods for detecting infectious agents, providing information about the viability status of such infectious agents and for determining drug susceptibility. In certain embodiments, the present invention employs techniques involving nucleic acid amplification-based microbial identification together with phage-based biological detection of drug resistance. The methods of the invention are suitable for all microbes and infectious agents, including bacterial agents such as Mycobacteria.
摘要翻译： 本发明涉及用于改善感染因子和微生物检测的方法和组合物。 特别地，本发明提供了用于检测感染因子的新方法，提供关于这种感染剂的生存状态的信息和用于确定药物敏感性。 在某些实施方案中，本发明使用涉及基于核酸扩增的微生物鉴定以及基于噬菌体的药物抗性生物检测的技术。 本发明的方法适用于所有微生物和感染因子，包括细菌剂如分枝杆菌。
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3.发明申请Methods and compositions for determining the pathogenic status of infectious agents 有权用于确定感染性病原体状态的方法和组合物公开(公告)号：US20090047658A1
公开(公告)日：2009-02-19
申请号：US12080929
申请日：2008-04-07
CPC分类号： C12Q1/689
摘要： Methods and compositions for the detection of disease caused by infectious agents and microbes are provided. In particular, methods and compositions comprising novel combinations of nucleic acid amplification and drug susceptibility technologies are provided. In certain embodiments, the present invention enables the detection of infectious agents and microbes as well as providing information concerning the viability status of the agent or microbe. In one embodiment, the present invention is used for the detection of mycobacterial infections, including, but not limited to, tuberculosis.
摘要翻译： 提供了用于检测感染性和微生物引起的疾病的方法和组合物。 特别地，提供了包含核酸扩增和药物敏感性技术的新组合的方法和组合物。 在某些实施方案中，本发明能够检测感染因子和微生物以及提供关于试剂或微生物的活力状态的信息。 在一个实施方案中，本发明用于检测分枝杆菌感染，包括但不限于结核病。
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4.发明授权Methods and compositions for determining the pathogenic status of infectious agents 有权用于确定感染因子的致病状态的方法和组合物公开(公告)号：US07919234B2
公开(公告)日：2011-04-05
申请号：US12080929
申请日：2008-04-07
CPC分类号： C12Q1/689
摘要： Methods and compositions for the detection of disease caused by infectious agents and microbes are provided. In particular, methods and compositions comprising novel combinations of nucleic acid amplification and drug susceptibility technologies are provided. In certain embodiments, the present invention enables the detection of infectious agents and microbes as well as providing information concerning the viability status of the agent or microbe. In one embodiment, the present invention is used for the detection of mycobacterial infections, including, but not limited to, tuberculosis.
摘要翻译： 提供了用于检测感染性和微生物引起的疾病的方法和组合物。 特别地，提供了包含核酸扩增和药物敏感性技术的新组合的方法和组合物。 在某些实施方案中，本发明能够检测感染因子和微生物以及提供关于试剂或微生物的活力状态的信息。 在一个实施方案中，本发明用于检测分枝杆菌感染，包括但不限于结核病。
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