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公开(公告)号:US06841547B2
公开(公告)日:2005-01-11
申请号:US10377088
申请日:2003-02-28
申请人: David Brown , Lorne M. Golub , Hsi-Ming Lee , Robert Greenwald , Maria Ryan , Kavita Desai
发明人: David Brown , Lorne M. Golub , Hsi-Ming Lee , Robert Greenwald , Maria Ryan , Kavita Desai
IPC分类号: A61K31/65
CPC分类号: A61K31/65
摘要: The present invention relates to a method for decreasing elevated serum/plasma LDL-cholesterol levels or LDL-cholesterol levels and CRP levels in a mammal in need thereof. The methods comprises administering an effective amount of a tetracycline formulation. In one embodiment, the tetracycline formulation is a non-antibacterial tetracycline. In another embodiment, the tetracycline formulation is an antibacterial tetracycline at a sub-antibacterial amount.
摘要翻译: 本发明涉及降低有需要的哺乳动物中升高的血清/血浆LDL-胆固醇水平或LDL-胆固醇水平和CRP水平的方法。 所述方法包括施用有效量的四环素制剂。 在一个实施方案中,四环素制剂是非抗菌四环素。 在另一个实施方案中,四环素制剂是亚抗菌量的抗菌四环素。