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公开(公告)号:US20090028798A1
公开(公告)日:2009-01-29
申请号:US11997236
申请日:2006-08-10
申请人: James B. Mitchell , Murali K. Cherukuri , John A. Cook , Fuminori Hyodo , Alan P. Koretsky , Ken-Ichiro Matsumoto , Sankaran Subramanian , David A. Wink
发明人: James B. Mitchell , Murali K. Cherukuri , John A. Cook , Fuminori Hyodo , Alan P. Koretsky , Ken-Ichiro Matsumoto , Sankaran Subramanian , David A. Wink
IPC分类号: A61K49/08
摘要: Disclosed is a method for determining the redox status of a region of interest in an animal tissue. The method includes administering a nitroxyl contrast agent to the region of interest, obtaining a magnetic resonance image of the region of interest, determining the amount of reduced nitroxyl contrast agent in the region of interest, and thereby determining the redox status of the region of interest.
摘要翻译: 公开了一种用于确定动物组织中感兴趣区域的氧化还原状态的方法。 该方法包括向感兴趣区域施用硝酰基造影剂,获得感兴趣区域的磁共振图像,确定感兴趣区域中还原的硝酰基造影剂的量,从而确定感兴趣区域的氧化还原状态 。