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1.发明授权Preparation for prophylaxis or treatment of renal diseases containing sulfated polysaccharide 失效预防或治疗含有硫酸化多糖的肾脏疾病的制剂
公开(公告)号：US5981509A
公开(公告)日：1999-11-09
申请号：US859293
申请日：1997-05-20
申请人： Kazuo Akima , Kenichi Shikata , Hirofumi Makino , Zensuke Ota , Kyoji Hirata , Masayuki Miyasaka , Yasuo Suzuki
发明人： Kazuo Akima , Kenichi Shikata , Hirofumi Makino , Zensuke Ota , Kyoji Hirata , Masayuki Miyasaka , Yasuo Suzuki
IPC分类号： A61K31/737 , A61K31/715 , A61K31/725
CPC分类号： A61K31/737
摘要： The specification relates to a preparation for the prophylaxis or treatment of renal diseases, and a method for the prophylaxis or treatment of renal diseases, and specifically, it relates to the above preparation and method using a sulfated polysaccharide as an active ingredient.
摘要翻译： 本说明书涉及用于预防或治疗肾脏疾病的制剂，以及预防或治疗肾脏疾病的方法，具体涉及使用硫酸化多糖作为活性成分的上述制备方法。
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公开(公告)号：US09808023B2
公开(公告)日：2017-11-07
申请号：US12281402
申请日：2007-03-01
IPC分类号： A23F3/20
摘要： Provided is a process for producing a tea extract having a high recovery rate of non-polymer catechins, a low caffeine content and an improved taste and color tone. As one embodiment of this invention provides, there is provided a process for producing a purified tea extract by adsorbing a tea extract on a synthetic adsorbent, bringing an aqueous solution of an organic solvent or a basic aqueous solution into contact with the synthetic adsorbent to elute non-polymer catechins, and then bringing the eluate into contact with activated carbon in an aqueous solution of an organic solvent.
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公开(公告)号：US20090041921A1
公开(公告)日：2009-02-12
申请号：US12281402
申请日：2007-03-01
摘要： Provided is a process for producing a tea extract having a high recovery rate of non-polymer catechins, a low caffeine content and an improved taste and color tone. As one embodiment of this invention provides, there is provided a process for producing a purified tea extract by adsorbing a tea extract on a synthetic adsorbent, bringing an aqueous solution of an organic solvent or a basic aqueous solution into contact with the synthetic adsorbent to elute non-polymer catechins, and then bringing the eluate into contact with activated carbon in an aqueous solution of an organic solvent.
摘要翻译： 本发明提供一种具有高聚合物儿茶素类回收率高，咖啡因含量低，味道色调好的茶提取物的制造方法。 作为本发明的一个实施方式，提供了一种通过将茶提取物吸附在合成吸附剂上来制备纯化茶提取物的方法，使有机溶剂或碱性水溶液的水溶液与合成吸附剂接触以洗脱 非聚合物儿茶素类，然后使洗脱液与有机溶剂的水溶液中的活性炭接触。
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公开(公告)号：US20120244255A1
公开(公告)日：2012-09-27
申请号：US13514828
申请日：2010-12-08
申请人： Kenichi Shikata , Hitoshi Sato
发明人： Kenichi Shikata , Hitoshi Sato
IPC分类号： A23F3/16
CPC分类号： A23F3/205
摘要： Provided is a method for producing a purified tea extract, which can satisfy both the yield of the non-polymer catechins and the removal rate of gallic acid at high levels. The method is characterized in that a tea extract, which contains an aqueous solution of an organic solvent, brought into contact with an anion exchange resin.
摘要翻译： 本发明提供了能够同时满足非聚合型儿茶素类的收率和高水平的没食子酸的去除率的纯化茶提取物的制造方法。 该方法的特征在于，含有有机溶剂的水溶液的茶提取物与阴离子交换树脂接触。
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公开(公告)号：US20120121761A1
公开(公告)日：2012-05-17
申请号：US12672302
申请日：2008-08-07
申请人： Masahiro Fukuda , Eri Itaya , Hirokazu Takahashi , Miwa Ogasawara , Hitoshi Sato , Kenichi Shikata , Keiji Shibata
发明人： Masahiro Fukuda , Eri Itaya , Hirokazu Takahashi , Miwa Ogasawara , Hitoshi Sato , Kenichi Shikata , Keiji Shibata
摘要： This invention relates to a process for producing a tea extract. The process includes subjecting a first tea extract solution, which has been obtained from tea, to solid-liquid separation so that a turbidity becomes 200 NTU or lower when a concentration of non-polymer catechins is adjusted to 1 wt %, thereby obtaining a second tea extract solution in which a concentration of (A) non-polymer catechins is from 0.2 to 5 wt % and a concentration of non-polymer catechins in solid content is from 15 to 80 wt %; and then subjecting the second tea extract solution to a heat treatment at a temperature of from 95 to 140° C. for an F value of from 0.05 to 40 min.
摘要翻译： 本发明涉及茶提取物的制造方法。 该方法包括使得从茶获得的第一茶提取物溶液进行固液分离，使得当非聚合型儿茶素类的浓度调节至1重量％时，浊度变为200NTU或更低，从而获得第二 （A）非聚合型儿茶素类的浓度为0.2〜5重量％，固体成分中的非聚合物儿茶素类的浓度为15〜80重量％的茶提取液， 然后在95〜140℃的温度下对第二茶提取液进行热处理，F值为0.05〜40分钟。
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公开(公告)号：US20130273220A1
公开(公告)日：2013-10-17
申请号：US13977036
申请日：2011-12-28
申请人： Takuma Ito , Kenichi Shikata , Hitoshi Sato , Eizo Maruyama
发明人： Takuma Ito , Kenichi Shikata , Hitoshi Sato , Eizo Maruyama
IPC分类号： A23F3/20
CPC分类号： A23F3/205
摘要： Provided is a production method for a purified tea extract, which enables efficiently removing gallic acid and collecting the non-polymer catechins in a high yield without impairing original taste and flavor of tea. The production method for a purified tea extract according to the present invention comprises bringing a tea extract into contact with an OH-type anion exchange resin and an H-type cation exchange resin.
摘要翻译： 提供了一种纯化茶提取物的制备方法，其能够高效率地除去没食子酸并收集非聚合型儿茶素，而不会损害茶的原始味道和风味。 根据本发明的纯化茶提取物的制备方法包括使茶提取物与OH型阴离子交换树脂和H型阳离子交换树脂接触。
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公开(公告)号：US20100278972A1
公开(公告)日：2010-11-04
申请号：US12810477
申请日：2008-12-26
申请人： Kenichi Shikata , Hitoshi Sato , Keiji Shibata
发明人： Kenichi Shikata , Hitoshi Sato , Keiji Shibata
IPC分类号： A23F3/16
摘要： A purified tea extract with suppressed bitterness and astringency is economically produced in high yield and high efficiency by dramatically accelerating an enzyme reaction with addition of tannase in a smaller amount. A process of the present invention for the production of a purified tea extract includes a first step which comprises eliminating water-insoluble solids from a first tea extract and then obtaining a second tea extract so that a turbidity falls into a range from 0.1 to 100 NTU when a concentration of the non-polymer catechins is adjusted to 0.7 wt %, and a second step which comprises subjecting the second tea extract at a concentration of the non-polymer catechins of from 0.05 to 4.0 wt % to tannase treatment.
摘要翻译： 具有抑制苦味和涩味的纯化茶提取物通过以较少的量添加鞣酸酶显着加速酶反应而以高产率和高效率经济地产生。 用于生产纯化茶提取物的本发明方法包括：第一步，其包括从第一茶提取物中除去水不溶性固体，然后获得第二茶提取物，使浊度落入0.1至100NTU 当将非聚合型儿茶素类的浓度调整为0.7重量％时，将包含0.05〜4.0重量％的非聚合型儿茶素类的浓度的第二茶提取物进行脱水处理的第二工序。
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