Magnetically-controllable delivery system for therapeutic agents
    1.
    发明申请
    Magnetically-controllable delivery system for therapeutic agents 审中-公开
    用于治疗剂的磁控制递送系统

    公开(公告)号:US20060041182A1

    公开(公告)日:2006-02-23

    申请号:US11210173

    申请日:2005-08-22

    IPC分类号: A61N2/10 A61F2/06 A61F2/28

    摘要: A magnetic delivery system for delivering a magnetizable particle to a location in a body, the device includes a magnetizable object implanted in the body, wherein the magnetizable object includes a plurality of segments distributed throughout the magnetizable object and wherein the segments are configured to provide a magnetic gradient for attracting the magnetizable particle and an external source of a magnetic field capable of (i) magnetizing the magnetizable particle and (ii) increasing a degree of magnetization of the magnetizable object and thereby creating the magnetic gradient. A drug delivery system including the magnetic delivery system and a magnetizable particle associated with a therapeutic agent and/or a cell. A cell delivery system based on the magnetic delivery system and a magnetizable particle associated with a cell. A method of using the magnetic delivery system for delivery of a therapeutic agent and/or a cell to a targeted location in a body.

    摘要翻译: 一种用于将可磁化颗粒输送到身体中的位置的磁性传送系统,该装置包括植入体内的可磁化物体,其中可磁化物体包括分布在整个可磁化物体上的多个区段,并且其中该区段被配置成提供 用于吸引可磁化颗粒的磁梯度和能够(i)磁化可磁化颗粒的磁场的外部源,和(ii)增加可磁化物体的磁化程度,从而产生磁梯度。 药物递送系统,包括磁性递送系统和与治疗剂和/或细胞相关联的可磁化颗粒。 基于磁传递系统的细胞递送系统和与细胞相关联的可磁化颗粒。 一种使用磁性递送系统将治疗剂和/或细胞输送到体内目标位置的方法。