公开(公告)号：US20100150886A1

公开(公告)日：2010-06-17

申请号：US11990443

申请日：2006-08-10

Applicant: Takahiro Marui ,  Kinuko Magamine ,  Nobuke Muraki ,  Akiko Kato ,  Tatsuji Enoki ,  Hiroaki Sagawa ,  Ikunoshin Kato

Inventor： Takahiro Marui ,  Kinuko Magamine ,  Nobuke Muraki ,  Akiko Kato ,  Tatsuji Enoki ,  Hiroaki Sagawa ,  Ikunoshin Kato

IPC: A61K45/00 ,  C12N5/078 ,  A61P37/04

CPC classification number: A61K35/17 ,  A61K35/26 ,  A61K2039/5154 ,  C07K14/78 ,  C12N5/0636 ,  C12N2501/51 ,  C12N2501/515 ,  C12N2501/58 ,  C12N2531/00 ,  C12N2533/52 ,  G01N33/547

Abstract: A method for preparing lymphocytes characterized in that the method comprises the step of carrying out expansion in the presence of (a) fibronectin, a fragment thereof or a mixture thereof, (b) a CD3 ligand, and (c) a CD28 ligand.

Abstract translation: 一种制备淋巴细胞的方法，其特征在于该方法包括在（a）纤连蛋白，其片段或其混合物，（b）CD3配体和（c）CD28配体存在下进行扩增的步骤。