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公开(公告)号：US5436162A
公开(公告)日：1995-07-25
申请号：US945240
申请日：1992-09-15
申请人： Konrad Heckl , Walter Spevak , Elinborg Ostermann , Andreas Zophel , Edeltraud Krystek , Ingrid Maurer-Fogy , Maria J. Wiche-Castanon , Christian Stratowa , Rudolf Hauptmann
发明人： Konrad Heckl , Walter Spevak , Elinborg Ostermann , Andreas Zophel , Edeltraud Krystek , Ingrid Maurer-Fogy , Maria J. Wiche-Castanon , Christian Stratowa , Rudolf Hauptmann
IPC分类号： C12N1/20 , A61K38/44 , A61K38/45 , A61P29/00 , A61P37/08 , C07H21/04 , C07K14/00 , C12N1/16 , C12N1/19 , C12N1/21 , C12N9/02 , C12N15/09 , C12N15/53 , C12N15/62 , C12P21/00 , C12R1/19 , C12R1/865 , C12R1/91 , C12N15/63 , C12N15/81
CPC分类号： C12N9/0089 , C12N15/625 , C07K2319/02 , C07K2319/07
摘要： The present invention relates to a method of preparing human Mn-superoxide dismutase (hMn-SOD) by genetic engineering, the DNA sequences which code for this enzyme, suitable vectors which contain these DNA sequences and host cells which can express these DNA sequences, and the enzyme hMn-SOD itself. Suggestions as to the use of this enzyme are also described.
摘要翻译： 本发明涉及通过遗传工程制备人类Mn超氧化物歧化酶（hMn-SOD）的方法，编码该酶的DNA序列，含有这些DNA序列的合适载体和可表达这些DNA序列的宿主细胞，以及 酶hMn-SOD本身。 还描述了关于使用该酶的建议。
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公开(公告)号：US5260204A
公开(公告)日：1993-11-09
申请号：US944939
申请日：1992-09-15
申请人： Konrad Heckl , Walter Spevak , Elinborg Ostermann , Andreas Zophel , Edeltraud Krystek , Ingrid Maurer-Fogy , Maria J. Wiche-Castanon , Christian Stratowa , Rudolf Hauptmann
发明人： Konrad Heckl , Walter Spevak , Elinborg Ostermann , Andreas Zophel , Edeltraud Krystek , Ingrid Maurer-Fogy , Maria J. Wiche-Castanon , Christian Stratowa , Rudolf Hauptmann
CPC分类号： C12N9/0089 , C12N15/625 , C07K2319/02 , C07K2319/07
摘要： The present invention relates to a method of preparing human Mn-superoxide dismutase (hMn-SOD) by genetic engineering, the DNA sequences which code for this enzyme, suitable vectors which contain these DNA sequences and host cells which can express these DNA sequences, and the enzyme hMn-SOD itself. Suggestions as to the use of this enzyme are also described.
摘要翻译： 本发明涉及通过遗传工程制备人类Mn超氧化物歧化酶（hMn-SOD）的方法，编码该酶的DNA序列，含有这些DNA序列的合适载体和可表达这些DNA序列的宿主细胞，以及 酶hMn-SOD本身。 还描述了关于使用该酶的建议。
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公开(公告)号：US5589371A
公开(公告)日：1996-12-31
申请号：US413367
申请日：1995-03-30
申请人： Konrad Heckl , Walter Spevak , Elinborg Ostermann , Andreas Zophel , Edeltraud Krystek , Ingrid Maurer-Fogy , Maria J. Wiche-Castanon , Christian Stratowa , Rudolf Hauptmann
发明人： Konrad Heckl , Walter Spevak , Elinborg Ostermann , Andreas Zophel , Edeltraud Krystek , Ingrid Maurer-Fogy , Maria J. Wiche-Castanon , Christian Stratowa , Rudolf Hauptmann
IPC分类号： C12N1/20 , A61K38/44 , A61K38/45 , A61P29/00 , A61P37/08 , C07H21/04 , C07K14/00 , C12N1/16 , C12N1/19 , C12N1/21 , C12N9/02 , C12N15/09 , C12N15/53 , C12N15/62 , C12P21/00 , C12R1/19 , C12R1/865 , C12R1/91
CPC分类号： C12N9/0089 , C12N15/625 , C07K2319/02 , C07K2319/07
摘要： The present invention relates to a method of preparing human Mn-superoxide dismutase (hMn-SOD) by genetic engineering, the DNA sequences which code for this enzyme, suitable vectors which contain these DNA sequences and host cells which can express these DNA sequences, and the enzyme hMn-SOD itself. Suggestions as to the use of this enzyme are also described.
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公开(公告)号：US5240847A
公开(公告)日：1993-08-31
申请号：US167261
申请日：1988-03-11
申请人： Konrad Heckl , Walter Spevak , Elinborg Ostermann , Andreas Zophel , Edeltraud Krystek , Ingrid Maurer-Fogy , Maria J. Wiche-Castanon , Christian Stratowa , Rudolf Hauptmann
发明人： Konrad Heckl , Walter Spevak , Elinborg Ostermann , Andreas Zophel , Edeltraud Krystek , Ingrid Maurer-Fogy , Maria J. Wiche-Castanon , Christian Stratowa , Rudolf Hauptmann
IPC分类号： C12N1/20 , A61K38/44 , A61K38/45 , A61P29/00 , A61P37/08 , C07H21/04 , C07K14/00 , C12N1/16 , C12N1/19 , C12N1/21 , C12N9/02 , C12N15/09 , C12N15/53 , C12N15/62 , C12P21/00 , C12R1/19 , C12R1/865 , C12R1/91
CPC分类号： C12N9/0089 , C12N15/625 , C07K2319/02 , C07K2319/07
摘要： The present invention relates to a method of preparing human Mn-superoxide dismutase (hMn-SOD) by genetic engineering, the DNA sequences which code for this enzyme, suitable vectors which contain these DNA sequences and host cells which can express these DNA sequences, and the enzyme hMn-SOD itself. Suggestions as to the use of this enzyme are also described.
摘要翻译： 本发明涉及通过遗传工程制备人类Mn超氧化物歧化酶（hMn-SOD）的方法，编码该酶的DNA序列，含有这些DNA序列的合适载体和可表达这些DNA序列的宿主细胞，以及 酶hMn-SOD本身。 还描述了关于使用该酶的建议。
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