公开(公告)号：US20060190184A1

公开(公告)日：2006-08-24

申请号：US11064302

申请日：2005-02-23

申请人： Maciek Sasinowski ,  Krista Miller ,  Heather Sasinowska ,  Jason Miller

发明人： Maciek Sasinowski ,  Krista Miller ,  Heather Sasinowska ,  Jason Miller

IPC分类号： G06F19/00 ,  G06F17/21

CPC分类号： G16B50/00 ,  G16B5/00 ,  G16B45/00

摘要： The current invention provides a visual or audio-visual programming environment for life science and bioinformatics. It is based on the VIBE platform, which is a flexible, extensible, and integrated workflow construction and management platform. The current invention enables researchers to consolidate molecular profiling data from complementary experimental techniques, intelligently reduce the volume of the data, construct disease-specific molecular fingerprints, construct relationship networks among functionally significant genomic, transcriptomic, metabonomic, and proteomic data, integrate information from existing biological databases into those networks, optimize the process through iterative feedback loops, and to generate and validate hypotheses based on the above process. The uses of this integrative, systems-based approach include, but are not limited to, the identification of potential biomarkers, characterization and classification of diseases and pathogens, and discovery of drug targets.

摘要翻译： 本发明为生命科学和生物信息学提供视觉或视听编程环境。 它是基于VIBE平台，它是一个灵活，可扩展，集成的工作流构建和管理平台。 本发明使研究人员能够从互补实验技术中整合分子谱分析数据，智能地减少数据量，构建疾病特异性分子指纹，在功能重要的基因组，转录组学，代谢组学和蛋白质组学数据之间建立关系网络，整合现有的信息 生物数据库进入这些网络，通过迭代反馈循环优化过程，并根据上述过程生成和验证假设。 这种综合的基于系统的方法的使用包括但不限于识别潜在的生物标志物，疾病和病原体的表征和分类以及药物靶标的发现。

公开(公告)号：US20050282137A1

公开(公告)日：2005-12-22

申请号：US10872056

申请日：2004-06-19

申请人： Maciek Sasinowski ,  Krista Miller ,  Heather Sasinowska ,  Jason Miller ,  Kristina Gleason

发明人： Maciek Sasinowski ,  Krista Miller ,  Heather Sasinowska ,  Jason Miller ,  Kristina Gleason

IPC分类号： G09B3/00

CPC分类号： G09B5/00 ,  G09B7/02

摘要： The current invention is a visual or audio-visual programming environment for life science and bioinformatics developed for educational purposes. This programming environment incorporates novel educational features including: an integrated overview page, quick reference guide, introductory video, hot-linked glossary, intelligent personalized tutor, library of primers, multimedia tutorials, entertainment features, educational error messages, tracking system(s), multimedia assessment(s), and a lesson planner. The supporting client-server as well as client-only architecture includes drag-and-drop workflow pipeline construction for bioinformatics analysis using built-in user-defined or third party services (modules) as well as a software development kit (SDK), sharing and auto-update utility.

摘要翻译： 本发明是为教育目的开发的用于生命科学和生物信息学的视觉或视听编程环境。 这个编程环境融合了新颖的教育功能，包括：综合概述页面，快速参考指南，介绍性视频，热链接词汇表，智能个性化导师，引文库，多媒体教程，娱乐功能，教育错误消息，跟踪系统， 多媒体评估和课程计划。 支持客户端服务器以及仅客户端架构包括使用内置用户定义或第三方服务（模块）的生物信息学分析的拖放式工作流管道构建以及软件开发工具包（SDK），共享 和自动更新实用程序。