公开(公告)号：US20100208061A1

公开(公告)日：2010-08-19

申请号：US12703843

申请日：2010-02-11

申请人： Kyu-sang LEE ,  Carl S. BROWN ,  Kyla TEPLITZ ,  Steve GOODSON

发明人： Kyu-sang LEE ,  Carl S. BROWN ,  Kyla TEPLITZ ,  Steve GOODSON

IPC分类号： H04N7/18 ,  G06K9/00

CPC分类号： G01N21/6452 ,  G01N21/6456 ,  G01N21/6486 ,  G06T7/75 ,  G06T2207/10056 ,  G06T2207/30024 ,  G06T2207/30204

摘要： An apparatus for scanning a biometric device includes a camera that scans the biometric device to generate images, and a computer that extracts data from the images. The computer measures three-dimensional locations of at least three different positions on a surface of the biometric device, determines one of a virtual approximation plane and a curved surface with respect to the surface of the biometric device based on the measured three-dimensional locations, determines imaging locations of two or more panels disposed on the biometric device based on the one of the virtual approximation plane and the curved surface, obtains individual images of the two or more panels by scanning the biometric device based on the determined imaging locations, and extracts overall data of the biometric device from the individual images of the two or more panels.

摘要翻译： 用于扫描生物测定装置的装置包括扫描生物测定装置以产生图像的相机以及从图像中提取数据的计算机。 计算机测量生物测定装置的表面上的至少三个不同位置的三维位置，基于测量的三维位置确定相对于生物测定装置的表面的虚拟近似平面和弯曲表面之一， 基于虚拟近似平面和曲面中的一个，确定设置在生物测定装置上的两个或更多个面板的成像位置，通过基于确定的成像位置扫描​​生物测定装置来获得两个或更多个面板的单独图像，并且提取 来自两个或更多个面板的各个图像的生物测定装置的总体数据。

公开(公告)号：US20130170024A1

公开(公告)日：2013-07-04

申请号：US13823217

申请日：2011-09-14

申请人： Kyla Teplitz ,  Carl Brown

发明人： Kyla Teplitz ,  Carl Brown

IPC分类号： G02B21/06

CPC分类号： G02B21/06 ,  G02B21/084

摘要： Oblique-illumination systems integrated with fluorescence microscopes and methods of using oblique illumination in fluorescence microscopy are disclosed. An oblique-illumination system is attached to a fluorescence microscope objective. The oblique-illumination system can be used to illuminate from any desired direction the surface of an object located at a fixed known offset away from a sample solution containing fluorescently tagged targets. Oblique illumination is used to illuminate features of the surface while epi-illumination is used to create fluorescent light emitted from the tagged targets. The combination of oblique illumination of the surface and epi-illumination of the targets enables capture of images of the surface features and the fluorescent targets so that the locations of the targets in the sample can be determined based on the locations of the surface features.

摘要翻译： 公开了与荧光显微镜集成的倾斜照明系统和在荧光显微镜中使用倾斜照明的方法。 倾斜照明系统附着在荧光显微镜物镜上。 倾斜照明系统可用于从任何所需方向照射位于距离含有荧光标记的靶的样品溶液固定的已知偏移的物体的表面。 斜照度用于照亮表面的特征，而外照射用于产生从标记的靶发射的荧光。 表面的倾斜照明和目标的外射照的组合使得能够捕获表面特征和荧光目标的图像，使得可以基于表面特征的位置来确定样品中靶的位置。

公开(公告)号：US08333932B2

公开(公告)日：2012-12-18

申请号：US12704163

申请日：2010-02-11

申请人： Kyu-sang Lee ,  Seong-ho Cho ,  Carl S. Brown ,  Kyla Teplitz

发明人： Kyu-sang Lee ,  Seong-ho Cho ,  Carl S. Brown ,  Kyla Teplitz

IPC分类号： G01N33/48

CPC分类号： B01J19/0046 ,  B01J2219/0054 ,  B01J2219/0056 ,  B01J2219/00608 ,  B01J2219/00693 ,  Y10T428/24802

摘要： A substrate includes; a fiducial mark disposed on the substrate, an area on the substrate on which a probe material is configured to be immobilized, the area being separated from the fiducial mark, and a probe immobilization compound disposed on the area on the substrate on which the probe material is configured to be immobilized, wherein the fiducial mark has a structure which reflects irradiated light at a greater intensity than an intensity of reflected irradiated light form the area on the substrate not corresponding to the fiducial mark.

摘要翻译： 基板包括： 设置在基板上的基准标记，基板上的被配置为固定的探针材料的区域，与基准标记分离的区域，以及设置在基板上的探针固定化合物上的探针固定化合物，探针材料 被配置为被固定，其中基准标记具有以比反射的照射光的强度更大的强度反射照射的光的结构，形成不对应于基准标记的基板上的区域。

公开(公告)号：US08848051B2

公开(公告)日：2014-09-30

申请号：US12703843

申请日：2010-02-11

申请人： Kyu-sang Lee ,  Carl S. Brown ,  Kyla Teplitz ,  Steve Goodson

发明人： Kyu-sang Lee ,  Carl S. Brown ,  Kyla Teplitz ,  Steve Goodson

IPC分类号： G01N21/55 ,  G01N21/64 ,  G06T7/00

CPC分类号： G01N21/6452 ,  G01N21/6456 ,  G01N21/6486 ,  G06T7/75 ,  G06T2207/10056 ,  G06T2207/30024 ,  G06T2207/30204

摘要： An apparatus for scanning a biometric device includes a camera that scans the biometric device to generate images, and a computer that extracts data from the images. The computer measures three-dimensional locations of at least three different positions on a surface of the biometric device, determines a virtual approximation plane or a curved surface with respect to the surface of the biometric device based on the measured three-dimensional locations, determines imaging locations of two or more panels disposed on the biometric device based on the virtual approximation plane or the curved surface, obtains individual images of the two or more panels by scanning the biometric device based on the determined imaging locations, and extracts overall data of the biometric device from the individual images of the two or more panels.

摘要翻译： 用于扫描生物测定装置的装置包括扫描生物测定装置以产生图像的相机以及从图像中提取数据的计算机。 计算机测量生物测定装置的表面上的至少三个不同位置的三维位置，基于测量的三维位置确定相对于生物测定装置的表面的虚拟近似平面或曲面，确定成像 基于虚拟近似平面或曲面设置在生物测定装置上的两个或更多个面板的位置通过基于确定的成像位置扫描​​生物测定装置来获得两个或更多个面板的单独图像，并且提取生物测定装置的总体数据 设备从两个或多个面板的各个图像。

公开(公告)号：US20100210475A1

公开(公告)日：2010-08-19

申请号：US12704163

申请日：2010-02-11

申请人： Kyu-sang LEE ,  Seong-ho CHO ,  Carl S. BROWN ,  Kyla TEPLITZ

发明人： Kyu-sang LEE ,  Seong-ho CHO ,  Carl S. BROWN ,  Kyla TEPLITZ

IPC分类号： C40B30/10 ,  B32B3/10 ,  C40B40/00 ,  G03F7/20

CPC分类号： B01J19/0046 ,  B01J2219/0054 ,  B01J2219/0056 ,  B01J2219/00608 ,  B01J2219/00693 ,  Y10T428/24802

摘要： A substrate includes; a fiducial mark disposed on the substrate, an area on the substrate on which a probe material is configured to be immobilized, the area being separated from the fiducial mark, and a probe immobilization compound disposed on the area on the substrate on which the probe material is configured to be immobilized, wherein the fiducial mark has a structure which reflects irradiated light at a greater intensity than an intensity of reflected irradiated light form the area on the substrate not corresponding to the fiducial mark.

摘要翻译： 基板包括： 设置在基板上的基准标记，基板上的被配置为固定的探针材料的区域，与基准标记分离的区域，以及设置在基板上的探针固定化合物上的探针固定化合物，探针材料 被配置为被固定，其中基准标记具有以比反射的照射光的强度更大的强度反射照射的光的结构，形成不对应于基准标记的基板上的区域。