公开(公告)号：US20060240496A1

公开(公告)日：2006-10-26

申请号：US11407415

申请日：2006-04-20

申请人： Lakshmi Anne ,  Vani Bodepudi

发明人： Lakshmi Anne ,  Vani Bodepudi

IPC分类号： G01N33/53 ,  C07K16/18 ,  C07K14/47

CPC分类号： G01N33/5308 ,  C07K16/44 ,  G01N2400/02

摘要： Ethyl glucuronide (“EtG”) analogs can be prepared for use as immunodiagnostic reagents and in immunodiagnostic protocols. The EtG analogs can be in the form of EtG-based immunogens, and EtG-based antigens. The EtG-based immunogens can be used for preparing anti-EtG antibodies, which can be used in immunoassays. Accordingly, improved immunoassay techniques for detecting EtG can be performed with the EtG-based antigens, and anti-EtG antibodies prepared from EtG-based immunogens.

摘要翻译： 可以制备葡萄糖醛酸葡萄糖苷（“EtG”）类似物用作免疫诊断试剂和免疫诊断方案。 EtG类似物可以是基于EtG的免疫原和EtG基抗原的形式。 基于EtG的免疫原可用于制备抗EtG抗体，可用于免疫测定。 因此，可以使用基于EtG的抗原和由EtG基免疫原制备的抗-EtG抗体来进行用于检测EtG的改进的免疫测定技术。

公开(公告)号：US06503726B2

公开(公告)日：2003-01-07

申请号：US09794789

申请日：2001-02-27

申请人： Lakshmi Anne ,  Weixing Luo ,  Ker-kong Tung

发明人： Lakshmi Anne ,  Weixing Luo ,  Ker-kong Tung

IPC分类号： C12Q128

CPC分类号： C12Q1/28 ,  Y10S435/97 ,  Y10T436/173845

摘要： A device and method to detect oxidant adulterants added to a sample to prevent detection of tetrahydrocannabinol and/or tetrahydrocannabinol metabolites. The device and method detect popularly available adulterants such as chromate and nitrite through their reaction with a chromogenic substrate for a peroxidase enzyme. The substrate may be applied to a pad. A change in color in the presence of the oxidant may be detected directly or indirectly. The device and method may be used to detect the presence of any oxidant adulterant and is not specific for only one or a few adulterants added to a urine sample submitted for drug testing.