公开(公告)号：US11992843B2

公开(公告)日：2024-05-28

申请号：US16816000

申请日：2020-03-11

Applicant: ABBOTT RAPID DIAGNOSTICS INTERNATIONAL UNLIMITED COMPANY

Inventor： Haipeng Hu ,  Jianfeng Wang

IPC: B01L3/00 ,  A61B10/00 ,  B65D41/04

CPC classification number: B01L3/508 ,  A61B10/0096 ,  B65D41/0471 ,  A61B10/0045 ,  B01L2200/025 ,  B01L2200/141 ,  B01L2300/042 ,  B01L2300/123 ,  B65D2203/12 ,  Y10T436/141111 ,  Y10T436/142222 ,  Y10T436/143333 ,  Y10T436/144444 ,  Y10T436/145555 ,  Y10T436/146666 ,  Y10T436/147777 ,  Y10T436/173076 ,  Y10T436/173845

Abstract: A device for detecting an analyte in a sample is provided, which comprises: a collecting chamber containing an opening for collecting a liquid sample; a detecting element for detecting an analyte in the liquid sample; and a lid for covering the opening of the collecting chamber. The device further comprises an indicating device thereon to indicate whether or not the lid covers at an appointed position. The operation of the device is very simple.

公开(公告)号：US10071067B2

公开(公告)日：2018-09-11

申请号：US15807668

申请日：2017-11-09

Applicant: The Procter & Gamble Company

Inventor： Allyn Michael Kaufmann ,  James Carl Grimm ,  Chelsay Lynn Brewster ,  Thomas Edward Huetter

IPC: A61K31/137 ,  A61K47/08 ,  A61K31/167 ,  A61K31/4402 ,  A61K31/485 ,  A61K9/00 ,  A61K9/08 ,  A61K31/138 ,  A61K31/192 ,  A61K47/10 ,  A61K47/26 ,  A61K47/36

CPC classification number: A61K31/137 ,  A61K9/0053 ,  A61K9/0095 ,  A61K9/08 ,  A61K31/138 ,  A61K31/167 ,  A61K31/192 ,  A61K31/4402 ,  A61K31/485 ,  A61K47/08 ,  A61K47/10 ,  A61K47/26 ,  A61K47/36 ,  Y10T436/173845

Abstract: An anise flavored liquid medication. The liquid medication contains phenylephrine and an anethole analog that is substantially free of aldehyde groups. In one example, the anethole analog can be 1-methoxy-4-n-propylbenzene.

公开(公告)号：US09977027B2

公开(公告)日：2018-05-22

申请号：US15318155

申请日：2015-06-08

Applicant: AAA Scientific Limited

Inventor： Michael Gerard Pallot ,  Leslie John Pitts ,  Philip Jones

IPC: G01N33/68 ,  G01N21/00 ,  G01N21/63 ,  G01N21/33 ,  G01N31/22 ,  G01N21/78

CPC classification number: G01N33/6839 ,  G01N21/00 ,  G01N21/33 ,  G01N21/63 ,  G01N21/78 ,  G01N31/22 ,  Y10T436/173845

Abstract: A method for analyzing one or more nitrogen-containing compounds is disclosed. In the method, a ninhydrin-containing composition is irradiated with UV light in an activation zone to produce a ninhydrin reagent containing hydrindantin. The ninhydrin reagent is passed to a reaction zone. In the reaction zone the ninhydrin reagent is contacted with the nitrogen-containing compounds.

公开(公告)号：US20170261482A1

公开(公告)日：2017-09-14

申请号：US15065480

申请日：2016-03-09

Applicant: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS

Inventor： Chanbasha BASHEER ,  Mousa Yaser AMAYREH

IPC: G01N33/18 ,  G01N30/72 ,  G01N30/06 ,  G01N35/10 ,  G01N30/24

CPC classification number: G01N33/1826 ,  G01N1/38 ,  G01N30/7206 ,  G01N30/88 ,  G01N2001/4061 ,  G01N2030/062 ,  G01N2030/884 ,  G01N2035/00554 ,  Y10T436/170769 ,  Y10T436/173845 ,  Y10T436/24 ,  Y10T436/255

Abstract: An automated dispersive liquid-liquid microextraction method of detecting and quanta N-nitrosamines in an aqueous sample. The method includes (a) extracting an aqueous solution containing the N-nitrosamines by mixing an extraction solvent and a dispersive solvent with the aqueous solution, such that the N-nitrosamines, or a portion thereof, re-distribute from the aqueous solution to the extraction solvent, (b) permitting the resulting mixture in (a) to form a two-phase mixture containing an aqueous phase containing the aqueous solution with reduced amounts of the N-nitrosamines and an organic phase containing the extraction solvent with the N-nitrosamines extracted from the aqueous solution, (c) injecting the organic phase, or a portion thereof, into an injection port of a gas chromatograph coupled with at least one mass spectrometer, and (d) analyzing the N-nitrosamines by gas chromatography and mass spectrometry to detect and quantify the concentration of the N-nitrosamines in the aqueous solution.

公开(公告)号：US09709572B2

公开(公告)日：2017-07-18

申请号：US14950961

申请日：2015-11-24

Applicant: Portland State University

Inventor： Robert Strongin ,  Xiaofeng Yang

IPC: C07D277/66 ,  G01N33/68 ,  G01N33/52 ,  C07D281/06 ,  C07D281/18 ,  G01N21/64

CPC classification number: G01N33/6815 ,  C07D277/66 ,  G01N21/6428 ,  G01N33/68 ,  G01N2021/6439 ,  Y10T436/17 ,  Y10T436/173845

Abstract: Embodiments of probes for selectively detecting compounds having a thiol group and an amino group, e.g., cysteine and/or homocysteine, are disclosed, along with methods and kits for detecting the compounds in neutral media with the probes. The probes have a structure according to the general formula where R1-R4 independently are hydrogen hydroxyl, halogen, thiol, thioether, lower aliphatic, or lower alkoxy, x is an integer from 0 to 4, and each R5 independently is halogen, hydroxyl, thiol, thioether, lower aliphatic, or lower alkoxy. Embodiments of the disclosed probes are capable of undergoing condensation/cyclization reactions with cysteine and/or homocysteine. Cysteine and/or homocysteine can be selectively detected and identified by determining fluorescence emission of the probes at characteristic wavelengths.

公开(公告)号：US09651479B2

公开(公告)日：2017-05-16

申请号：US14680574

申请日：2015-04-07

Applicant: Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG

Inventor： Edin Andelic ,  Ralf Bernhard ,  Michael Littmann

IPC: G01N21/31 ,  G01N21/63 ,  G01N21/78 ,  G01N33/00 ,  G01N21/27

CPC classification number: G01N21/31 ,  G01N21/274 ,  G01N21/314 ,  G01N21/63 ,  G01N21/78 ,  G01N21/783 ,  G01N33/0036 ,  G01N2201/062 ,  G01N2201/129 ,  Y10T436/16 ,  Y10T436/173076 ,  Y10T436/173845

Abstract: A method and analyzer for determining a measured value of a measured variable of process automation technology in a liquid or gaseous medium by means of an optical sensor includes taking a sample of the medium; mixing the sample with one or more reagents; supplying an emitter of the optical sensor with an exciter signal for producing sent light, wherein the sent light by interaction with the mixed sample is converted into received light as a function of the measured variable; producing a receiver signal by means of a receiver of the optical sensor from the converted, received light; and determining the measured value based on the receiver signal and a calibration function, which includes a term which takes aging of the reagents into consideration.

公开(公告)号：US09588091B2

公开(公告)日：2017-03-07

申请号：US14721543

申请日：2015-05-26

Applicant: FLIR DETECTION, INC.

Inventor： Laura Beth Wald ,  Gregory Charles Frye-Mason

IPC: G01N21/76 ,  G01N31/22 ,  G01N21/64

CPC classification number: G01N31/227 ,  G01N21/643 ,  G01N31/22 ,  G01N2201/062 ,  Y10T436/173076 ,  Y10T436/173845

Abstract: The present invention provides methods for determining the presence of oxidizing salts. According to the current invention, analyte is collected on a swipe and subsequently heated to a temperature sufficient to release a detectible vapor phase component of the oxidizing salt. The vapor phase component passes reacts with a pH sensitive molecule. Reaction of the vapor phase product with the pH sensitive molecule produces a detectible change in response intensity.

Abstract translation: 本发明提供了确定氧化盐存在的方法。 根据本发明，将分析物收集在刷毛上，随后加热到足以释放氧化盐的可检测气相成分的温度。 气相组分通过与pH敏感分子反应。 气相产物与pH敏感分子的反应产生响应强度的可检测变化。

公开(公告)号：US09575038B2

公开(公告)日：2017-02-21

申请号：US15000196

申请日：2016-01-19

Applicant: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES

Inventor： Kenneth G. Furton ,  Katylynn Beltz

IPC: G01N33/00 ,  A01K15/02 ,  F41H11/132

CPC classification number: G01N33/0006 ,  A01K15/02 ,  F41H11/132 ,  G01N33/0001 ,  Y10T436/173845 ,  Y10T436/196666

Abstract: A method of calibrating a biological detector can include training a biological detector to detect a calibration compound, wherein the calibration compound comprises an odor that is detectable by the biological detector and is not used in an environment for which the biological detector is trained to detect odors, presenting the biological detector with a device comprising the calibration compound, and determining whether the biological detector will alert to the calibration compound.

Abstract translation: 校准生物检测器的方法可以包括训练生物检测器以检测校准化合物，其中校准化合物包含可被生物检测器检测到的气味，并且不用于生物检测器被检测以检测气味的环境 向所述生物检测器提供包括所述校准化合物的装置，以及确定所述生物检测器是否将警告所述校准化合物。

公开(公告)号：US09528976B2

公开(公告)日：2016-12-27

申请号：US14765649

申请日：2014-02-28

Applicant: St. Jude Children's Research Hospital

Inventor： Amar K. Pani ,  Richard Jay Smeyne

IPC: G01N27/42 ,  G01N33/487 ,  A61K31/52 ,  B01D15/32 ,  G01N30/34 ,  G01N30/64 ,  G01N30/88

CPC classification number: G01N33/48707 ,  A61K31/52 ,  B01D15/327 ,  G01N27/423 ,  G01N30/34 ,  G01N30/64 ,  G01N2030/8827 ,  Y10T436/141111 ,  Y10T436/142222 ,  Y10T436/147777 ,  Y10T436/173845 ,  Y10T436/25375

Abstract: This invention relates is a label-free, enzyme-free, aptamer-free method for simultaneously measuring adenosine, and its intracellular metabolites, e.g., AMP, ADP and ATP, using high pressure liquid chromatography coupled to electrochemical detector (HPLC-ECD).

Abstract translation: 本发明涉及使用连接到电化学检测器（HPLC-ECD）的高压液相色谱法同时测量腺苷及其细胞内代谢物，例如AMP，ADP和ATP的无标记，无酶，无适体方法。

公开(公告)号：US20160341706A1

公开(公告)日：2016-11-24

申请号：US15229777

申请日：2016-08-05

Applicant: RAPTOR PHARMACEUTICALS INC.

Inventor： Kathlene Powell ,  Ramesh Muttavarapu

IPC: G01N30/74 ,  G01N30/06 ,  G01N30/16 ,  G01N33/15

CPC classification number: G01N30/74 ,  B01D15/325 ,  G01N21/33 ,  G01N30/02 ,  G01N30/06 ,  G01N30/16 ,  G01N30/34 ,  G01N30/88 ,  G01N33/15 ,  G01N2030/027 ,  G01N2030/8818 ,  Y10T436/173845

Abstract: Methods of analyzing purity of compositions comprising cysteamine and detecting impurities in cysteamine compositions are described.