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1.Pharmaceutical compound capable of induce immune protective response against Dengue virus having the capsid protein of the Dengue virus 有权
标题翻译: 能够对具有登革热病毒衣壳蛋白的登革热病毒诱导免疫保护作用的药物化合物公开(公告)号:US07790173B2
公开(公告)日:2010-09-07
申请号:US12067129
申请日:2006-09-18
申请人: Laura Lazo Vázquez , Lisset Hermida Cruz , Carlos López Abarrategui , Beatriz de la Caridad Sierra Vázquez , Susana Vázquez Ramundo , Iris Valdez Prado , Gerardo Enrique Guillen Nieto , Maria Guadalupe Guzmán Tirado , Aida Zulueta Morales
发明人: Laura Lazo Vázquez , Lisset Hermida Cruz , Carlos López Abarrategui , Beatriz de la Caridad Sierra Vázquez , Susana Vázquez Ramundo , Iris Valdez Prado , Gerardo Enrique Guillen Nieto , Maria Guadalupe Guzmán Tirado , Aida Zulueta Morales
CPC分类号: A61K39/12 , A61K2039/55505 , A61K2039/55566 , C07K14/005 , C12N2770/24122 , C12N2770/24134 , Y02A50/386
摘要: This invention describes a pharmaceutical compound which has the capsid protein of Dengue virus and which is capable of inducing, in the receptor, a protective immune response before the viral challenge, without inducing the Ab-dependent enhancement phenomenon.
摘要翻译: 本发明描述了具有登革热病毒衣壳蛋白的能够在病毒攻击之前在受体中诱导保护性免疫应答而不诱导依赖于Ab的增强现象的药物化合物。