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公开(公告)号：US20080306131A1
公开(公告)日：2008-12-11
申请号：US12156504
申请日：2008-06-02
申请人： Laurel Rita Barbieri , Thomas Joseph Berrodin , Ramunas Bigelis , Li-Ping Chang , Deborah Marie Roll , Maya Prakash Singh , Matthew R. Yudt
发明人： Laurel Rita Barbieri , Thomas Joseph Berrodin , Ramunas Bigelis , Li-Ping Chang , Deborah Marie Roll , Maya Prakash Singh , Matthew R. Yudt
IPC分类号： A61K31/403 , C07D209/56 , C12P17/10 , A61P25/00 , C12N1/14
CPC分类号： C12P17/10 , C07D209/94 , C12R1/645
摘要： Compounds of the structure: are provided. Also provided are methods of using these compounds as progesterone receptor modulators. Also described are methods of producing these compounds from a Verticillium species.
摘要翻译： 提供结构化合物。 还提供了使用这些化合物作为孕酮受体调节剂的方法。 还描述了从轮枝孢属物种生产这些化合物的方法。
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![PYRROLO[4,3,2-DE]QUINOLIN-8-AMINE COMPOUNDS AND METHODS OF THEIR PREPARATION AND USE](/abs-image/US/2010/02/18/US20100041692A1/abs.jpg.150x150.jpg)
2.发明申请PYRROLO[4,3,2-DE]QUINOLIN-8-AMINE COMPOUNDS AND METHODS OF THEIR PREPARATION AND USE 有权吡咯烷[4,3,2-DE]喹啉-8-胺化合物及其制备和使用方法公开(公告)号：US20100041692A1
公开(公告)日：2010-02-18
申请号：US12539869
申请日：2009-08-12
申请人： Min He , Jeffrey Edwin Janso , Ker Yu , Leonard Alexander McDonald , Laurel Rita Barbieri , Ariamala Gopalsamy
发明人： Min He , Jeffrey Edwin Janso , Ker Yu , Leonard Alexander McDonald , Laurel Rita Barbieri , Ariamala Gopalsamy
IPC分类号： A61K31/437 , C07D471/06 , C12N1/20 , A61P35/00 , C12P17/18
CPC分类号： C07D471/06 , C12P17/182 , C12R1/04
摘要： The present invention relates to compounds of formula I: methods of their use, processes for their preparation and isolated actinomycetes strains capable of preparing pyrrolo[4,3,2-de]quinolin-8-amine compounds.
摘要翻译： 本发明涉及式I化合物：其使用方法，其制备方法和能够制备吡咯并[4,3,2-de]喹啉-8-胺化合物的分离的放线菌菌株。
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![Pyrrolo[4,3,2-de]quinolin-8-amine compounds and methods of their preparation and use](/abs-image/US/2013/07/16/US08486961B2/abs.jpg.150x150.jpg)
3.发明授权Pyrrolo[4,3,2-de]quinolin-8-amine compounds and methods of their preparation and use 有权吡咯并[4,3,2-de]喹啉-8-胺化合物及其制备和使用方法公开(公告)号：US08486961B2
公开(公告)日：2013-07-16
申请号：US12539869
申请日：2009-08-12
申请人： Min He , Jeffrey Edwin Janso , Ker Yu , Leonard Alexander McDonald , Laurel Rita Barbieri , Ariamala Gopalsamy
发明人： Min He , Jeffrey Edwin Janso , Ker Yu , Leonard Alexander McDonald , Laurel Rita Barbieri , Ariamala Gopalsamy
IPC分类号： A61K31/437 , C07D471/06
CPC分类号： C07D471/06 , C12P17/182 , C12R1/04
摘要： The present invention relates to compounds of formula I: methods of their use, processes for their preparation and isolated actinomycetes strains capable of preparing pyrrolo[4,3,2-de]quinolin-8-amine compounds.
摘要翻译： 本发明涉及式I化合物：其使用方法，其制备方法和能够制备吡咯并[4,3,2-de]喹啉-8-胺化合物的分离的放线菌菌株。
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