公开(公告)号：US20240287022A1

公开(公告)日：2024-08-29

申请号：US18569352

申请日：2022-06-23

申请人： Merck Sharp & Dohme LLC

发明人： BRANDON D. CASH ,  GEORGE MADALIN GIAMBASU ,  ANDREW M. HAIDLE ,  BRETT A. HOPKINS ,  MATTHEW A. LARSEN ,  CHARLES A. LESBURG ,  PING LIU ,  RYAN QUIROZ ,  SULAGNA SANYAL ,  CATHERINE M. WHITE ,  XIN YAN ,  XIAO MEI ZHENG

IPC分类号： C07D401/06 ,  A61K31/4375 ,  A61K31/4704 ,  A61K31/4709 ,  A61K31/4725 ,  A61K31/4745 ,  A61K31/496 ,  A61K31/497 ,  A61K31/498 ,  A61K31/5025 ,  A61K31/519 ,  A61K31/538 ,  A61K31/5383 ,  C07D215/227 ,  C07D401/10 ,  C07D401/12 ,  C07D405/10 ,  C07D405/14 ,  C07D409/06 ,  C07D413/06 ,  C07D413/14 ,  C07D417/06 ,  C07D417/14 ,  C07D471/04 ,  C07D471/06 ,  C07D487/04 ,  C07D498/04 ,  C07D513/04

CPC分类号： C07D401/06 ,  A61K31/4375 ,  A61K31/4704 ,  A61K31/4709 ,  A61K31/4725 ,  A61K31/4745 ,  A61K31/496 ,  A61K31/497 ,  A61K31/498 ,  A61K31/5025 ,  A61K31/519 ,  A61K31/538 ,  A61K31/5383 ,  C07D215/227 ,  C07D401/10 ,  C07D401/12 ,  C07D405/10 ,  C07D405/14 ,  C07D409/06 ,  C07D413/06 ,  C07D413/14 ,  C07D417/06 ,  C07D417/14 ,  C07D471/04 ,  C07D471/06 ,  C07D487/04 ,  C07D498/04 ,  C07D513/04

摘要： Described herein are compounds of Formula I or a pharmaceutically acceptable salt thereof wherein A, E, U, X, Y, Z, R1, R2 and n are as defined herein. The compounds of Formula I act as IL4I1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for IL4I1-related diseases. Also provided herein are pharmaceutical compositions comprising the compounds of the invention, or their pharmaceutically acceptable salts, and a pharmaceutically acceptable carrier and methods of treatment with the compounds of the invention.

公开(公告)号：US20240217976A2

公开(公告)日：2024-07-04

申请号：US18063331

申请日：2022-12-08

申请人： JAPAN SCIENCE AND TECHNOLOGY AGENCY

发明人： Shohei SAITO ,  Hiroshi YABU ,  Hiroya ABE

IPC分类号： C07D487/04 ,  C07D313/14 ,  C07D471/06

CPC分类号： C07D487/04 ,  C07D313/14 ,  C07D471/06

摘要： Provided is a compound having higher fluorescence quantum yield and higher optical stability than a conventional FLAP and a polymer compound containing the compound.






A: seven or eight-membered ring structure,
Y1, Y2, Y3: halogen atom or the like,
a1: number of Y1, a2: number of Y2,
B: number of Y3,
0≤m and n≤3: when 1≤m≤3, Y1 may be substituted with a structure portion defined by m, when 1≤n≤3, Y2 may be substituted with a structure portion defined by n, and
B1, B2: Formulas (2-1) to (2-3):










C1, C2, C3: structure containing a cyclic hydrocarbon compound,
D1, D2, D3: substructure that inhibits aggregation,
E1, E2, E3: polymerizable substructure,
Z1: hydrogen atom or the like,

c: number of substituent groups Z1,


Z2, Z3: hydrogen atom or the like, and may form a ring with C2.

公开(公告)号：US20240189320A1

公开(公告)日：2024-06-13

申请号：US17270480

申请日：2019-08-22

申请人： ADLAI NORTYE BIOPHARMA CO., LTD.

发明人： Yufeng CHEN ,  Kaixuan CHEN ,  Pan LI ,  Canfeng LIU ,  Ji WANG ,  Qingchong QIU ,  Yang LU

IPC分类号： A61K31/5386 ,  A61K31/437 ,  A61K31/4985 ,  A61K31/5383 ,  A61K31/551 ,  A61K31/553 ,  A61P35/00 ,  C07D471/06 ,  C07D487/06 ,  C07D498/06 ,  C07D498/22 ,  C07D519/00

CPC分类号： A61K31/5386 ,  A61K31/437 ,  A61K31/4985 ,  A61K31/5383 ,  A61K31/551 ,  A61K31/553 ,  A61P35/00 ,  C07D471/06 ,  C07D487/06 ,  C07D498/06 ,  C07D498/22 ,  C07D519/00

摘要： The present invention provides compounds of Formula (I) or (II), pharmaceutical compositions thereof, and methods of using compounds of Formula (I) or (II) to prevent and/or treat immune-related disorders.

公开(公告)号：US12010914B2

公开(公告)日：2024-06-11

申请号：US17552649

申请日：2021-12-16

申请人： Arizona Board of Regents on behalf of Arizona State University

发明人： Jian Li ,  Daijun Feng

IPC分类号： H10K85/60 ,  C07D471/06 ,  C07D519/00 ,  C07F5/02 ,  C07F5/05 ,  C07F9/572 ,  C07F9/6561 ,  C09K11/06 ,  H10K50/11 ,  H10K101/10

CPC分类号： H10K85/6572 ,  C07D471/06 ,  C07D519/00 ,  C07F9/5728 ,  C07F9/6561 ,  C09K11/06 ,  H10K85/654 ,  C09K2211/1007 ,  C09K2211/1022 ,  C09K2211/1029 ,  C09K2211/1044 ,  C09K2211/1048 ,  C09K2211/1059 ,  C09K2211/1096 ,  H10K50/11 ,  H10K85/6565 ,  H10K2101/10 ,  Y02E10/549

摘要： Thermally activated delayed fluorescent compounds and uses thereof are described. The thermally activated delayed fluorescent compounds are an analogues of 9,10-dihydro-9,9-dimethylacridine compounds.

公开(公告)号：US20240180019A1

公开(公告)日：2024-05-30

申请号：US18208310

申请日：2023-06-12

申请人： Samsung Display Co., Ltd.

发明人： Seran Kim ,  Minsoo Choi ,  Hoilim Kim ,  Dongsun Yoo ,  Seokgyu Yoon ,  Jinsoo Jung ,  Hyejin Jung ,  Youngeun Choi

IPC分类号： H10K85/30 ,  C07D333/06 ,  C07D471/06 ,  C07D493/06 ,  C07D517/16 ,  C07F5/02 ,  C09K11/06 ,  H10K30/20 ,  H10K85/60

CPC分类号： H10K85/322 ,  C07D333/06 ,  C07D471/06 ,  C07D493/06 ,  C07D517/16 ,  C07F5/022 ,  C09K11/06 ,  H10K30/20 ,  H10K85/621 ,  H10K85/654 ,  H10K85/655 ,  H10K85/657 ,  H10K85/6572 ,  H10K85/6574 ,  H10K2101/40

摘要： Provided is an opto-electronic device including a first electrode, a second electrode facing the first electrode, and a photoactive layer arranged between the first electrode and the second electrode, wherein the photoactive layer includes a first layer and a second layer, the first layer including a first compound, and the second layer including a second compound that does not include a 5-membered ring, the first compound is an electron-donating compound, the second compound is an electron-accepting compound, and the opto-electronic device satisfies Equation 1:


0.1≤(E1LUMO−E2LUMO)/(E1LUMO−E1HOMO)≤0.5  Equation 1



wherein, in Equation 1, E1LUMO, E1HOMO, and E2LUMO are each as defined herein.

公开(公告)号：US20240116936A1

公开(公告)日：2024-04-11

申请号：US18462899

申请日：2023-09-07

申请人： BECKLEY PSYTECH LIMITED

发明人： Massimo MURATORE ,  Amir Lotfi MOGHADDAM ,  Christopher WONG

IPC分类号： C07D471/06 ,  A61K9/00 ,  A61K9/20 ,  C07D519/00

CPC分类号： C07D471/06 ,  A61K9/0019 ,  A61K9/0031 ,  A61K9/0056 ,  A61K9/006 ,  A61K9/0073 ,  A61K9/2072 ,  C07D519/00

摘要： This invention relates to pharmaceutically acceptable ergoline analogues and salts thereof. In particular, though not exclusively, the invention relates to formulations and uses of the same as a medicament.

公开(公告)号：US20240057476A1

公开(公告)日：2024-02-15

申请号：US18479306

申请日：2023-10-02

申请人： DUK SAN NEOLUX CO., LTD.

发明人： Ki Ho SO ,  Hyung Dong LEE ,  Dae Hwan OH ,  Won Sam KIM ,  Byoung Yeop KANG

IPC分类号： H10K85/60 ,  C07D405/12 ,  C07D409/12 ,  C07D411/12 ,  C07D411/14 ,  C07D471/06 ,  C07D513/10 ,  C09K11/06

CPC分类号： H10K85/636 ,  C07D405/12 ,  C07D409/12 ,  C07D411/12 ,  C07D411/14 ,  C07D471/06 ,  C07D513/10 ,  C09K11/06 ,  C09K2211/1018 ,  H10K50/15

摘要： Provided are a compound represented by Formula 1, an organic electric element comprising a first electrode, a second electrode, and an organic material layer formed between the first electrode and the second electrode, and an electronic device thereof, wherein by comprising compound represented by Formula 1 in the organic material layer, the driving voltage of the organic electric element can be lowered, and the luminous efficiency and life time, in particular, life time can be improved.

公开(公告)号：US11889756B2

公开(公告)日：2024-01-30

申请号：US16518346

申请日：2019-07-22

申请人： Samsung Display Co., Ltd.

发明人： Taekyung Kim ,  Sunwoo Kang ,  Pilgu Kang ,  Jiyoung Kwon ,  Soonchul Chang ,  Jaehoon Hwang

IPC分类号： H10K85/60 ,  C09K11/06 ,  C07D471/06 ,  C07D471/16 ,  H10K50/11 ,  H10K50/15 ,  H10K50/16 ,  H10K50/17 ,  H10K50/18 ,  H10K50/155 ,  H10K59/123 ,  H10K101/10

CPC分类号： H10K85/6572 ,  C07D471/06 ,  C07D471/16 ,  C09K11/06 ,  H10K85/615 ,  C09K2211/1018 ,  H10K50/11 ,  H10K50/15 ,  H10K50/155 ,  H10K50/16 ,  H10K50/17 ,  H10K50/171 ,  H10K50/18 ,  H10K59/123 ,  H10K2101/10

摘要： Provided are an organic light-emitting device having improved luminescent efficiency and a compound.

公开(公告)号：US11751471B2

公开(公告)日：2023-09-05

申请号：US17669798

申请日：2022-02-11

申请人： Crius Technology Group, Inc.

发明人： Phillip Bogdanovich

IPC分类号： H04B3/00 ,  H04L25/00 ,  H10K85/60 ,  H04W4/80 ,  H04L41/0833 ,  C07C209/60 ,  C07C211/61 ,  C07C217/80 ,  C07D209/86 ,  C07D209/94 ,  C07D213/06 ,  C07D213/16 ,  C07D219/02 ,  C07D221/08 ,  C07D223/26 ,  C07D265/38 ,  C07D279/22 ,  C07D307/91 ,  C07D307/93 ,  C07D311/80 ,  C07D333/76 ,  C07D405/04 ,  C07D405/12 ,  C07D407/12 ,  C07D471/06 ,  C07D487/04 ,  C09B19/00 ,  C09B21/00 ,  C09B57/00 ,  C09B69/00 ,  C09K11/06 ,  H04B3/56 ,  H04L12/28 ,  H04L43/00 ,  H05B47/18 ,  H05B47/19 ,  H05B47/185 ,  H05B47/115 ,  H05B47/105 ,  H04B3/54 ,  H04L12/40 ,  H04L43/08 ,  H05B47/175 ,  H10K50/11 ,  H10K50/15 ,  H10K50/17 ,  H10K50/18

CPC分类号： H10K85/633 ,  C07C209/60 ,  C07C211/61 ,  C07C217/80 ,  C07D209/86 ,  C07D209/94 ,  C07D213/06 ,  C07D213/16 ,  C07D219/02 ,  C07D221/08 ,  C07D223/26 ,  C07D265/38 ,  C07D279/22 ,  C07D307/91 ,  C07D307/93 ,  C07D311/80 ,  C07D333/76 ,  C07D405/04 ,  C07D405/12 ,  C07D407/12 ,  C07D471/06 ,  C07D487/04 ,  C09B19/00 ,  C09B21/00 ,  C09B57/008 ,  C09B69/008 ,  C09K11/06 ,  H04B3/54 ,  H04B3/56 ,  H04L12/2816 ,  H04L12/40 ,  H04L41/0833 ,  H04L43/00 ,  H04W4/80 ,  H05B47/105 ,  H05B47/115 ,  H05B47/18 ,  H05B47/185 ,  H05B47/19 ,  H10K85/636 ,  H10K85/6572 ,  H10K85/6574 ,  H10K85/6576 ,  C07C2601/14 ,  C07C2603/18 ,  C07C2603/26 ,  C07C2603/52 ,  C07C2603/54 ,  C07C2603/94 ,  C07C2603/97 ,  C09K2211/1007 ,  C09K2211/1011 ,  C09K2211/1014 ,  C09K2211/1029 ,  C09K2211/1088 ,  C09K2211/1092 ,  H04L43/08 ,  H04L2012/2843 ,  H05B47/175 ,  H10K50/11 ,  H10K50/15 ,  H10K50/17 ,  H10K50/18 ,  H10K85/615 ,  H10K85/626 ,  Y02E10/549

摘要： Methods, systems, and apparatus for monitoring and controlling electronic devices using wired and wireless protocols are disclosed. The systems and apparatus may monitor their environment for signals from electronic devices. The systems and apparatus may take and disambiguate the signals that are received from the devices in their environment to identify the devices and associate control signals with the devices. The systems and apparatus may use communication means to send control signals to the identified electronic devices. Multiple apparatuses or systems may be connected together into networks, including mesh networks, to make for a more robust architecture.

公开(公告)号：US20230203063A1

公开(公告)日：2023-06-29

申请号：US17807464

申请日：2022-06-17

申请人： Erasca, Inc.

发明人： Jun FENG ,  Jean-Michel VERNIER ,  Marcos GONZALEZ-LOPEZ ,  Benjamin JONES ,  Nicholas A. ISLEY ,  Ping CHEN

IPC分类号： C07D513/06 ,  C07D498/06 ,  C07D519/00 ,  C07D471/06 ,  C07D498/20

CPC分类号： C07D513/06 ,  C07D498/06 ,  C07D519/00 ,  C07D471/06 ,  C07D498/20 ,  C07B2200/05

摘要： A compound of Formula (I) is provided: (I) where the variables are defined herein.