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![Pyrazolo[3,4-b]pyridine compound, and its use as a PDE4 inhibitor](/abs-image/US/2010/05/04/US07709497B2/abs.jpg.150x150.jpg)
1.发明授权公开(公告)号：US07709497B2
公开(公告)日：2010-05-04
申请号：US10598838
申请日：2005-03-15
申请人： Siegfried Benjamin Christensen, IV , Caroline Mary Cook , Christopher David Edlin , Martin Redpath Johnson , Paul Spencer Jones , Mika Kristian Lindvall , Amyn Pyarali Sayani , Naimisha Trivedi , Lionel Trottet
发明人： Siegfried Benjamin Christensen, IV , Caroline Mary Cook , Christopher David Edlin , Martin Redpath Johnson , Paul Spencer Jones , Mika Kristian Lindvall , Amyn Pyarali Sayani , Naimisha Trivedi , Lionel Trottet
IPC分类号： A61K31/44 , A01N43/42 , C07D471/02 , C07D491/02 , C07D498/02
CPC分类号： C07D471/04
摘要： The invention provides 4-{[1-(aminocarbonyl)-4-piperidinyl]amino}-N-[(3,4-dimethylphenyl)methyl]-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide, which is the compound of formula (I): or a salt thereof.
摘要翻译： 本发明提供4 - {[1-（氨基羰基）-4-哌啶基]氨基} -N - [（3,4-二甲基苯基）甲基] -1-乙基-1H-吡唑并[3,4-b]吡啶-5 甲酰胺，其为式（I）的化合物或其盐。
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2.发明申请1,2,3-TRIAZOLE DERIVATIVES FOR USE AS STEAROYL-COA DESATURASE INHIBITORS 有权用作硬脂酰-CaA去饱和酶抑制剂的1,2,3-三唑衍生物公开(公告)号：US20100297054A1
公开(公告)日：2010-11-25
申请号：US12741637
申请日：2008-11-07
IPC分类号： A61K31/4192 , C07D249/04 , A61K38/16 , A61K31/4406 , A61K31/74 , A61K31/56 , A61K31/538 , A61P3/10 , A61P3/06 , A61P9/10 , A61P3/04 , A61P35/00 , A61P25/28 , A61P35/04 , A61P17/10
CPC分类号： C07D249/04 , C07D413/12
摘要： The present invention relates to substituted triazole compounds of the formula (I): and pharmaceutically acceptable salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds for modulating SCD activity.
摘要翻译： 本发明涉及含有它们的药物组合物及其在药物中的用途的式（I）的取代三唑化合物及其药学上可接受的盐。 特别地，本发明涉及用于调节SCD活性的化合物。
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![Pyrazolo[3,4-B]Pyridine Compound, and Its Use as a Pde4 Inhibitor](/abs-image/US/2007/12/06/US20070280971A1/abs.jpg.150x150.jpg)
3.发明申请公开(公告)号：US20070280971A1
公开(公告)日：2007-12-06
申请号：US10598838
申请日：2005-03-15
申请人： Siegfried Christensen , Caroline Cook , Christopher Edlin , Martin Johnson , Paul Jones , Mika Lindvall , Amyn Sayani , Naimisha Trivedi , Lionel Trottet
发明人： Siegfried Christensen , Caroline Cook , Christopher Edlin , Martin Johnson , Paul Jones , Mika Lindvall , Amyn Sayani , Naimisha Trivedi , Lionel Trottet
IPC分类号： A61K31/437 , A61K9/06 , A61K9/107 , A61P17/00 , A61P29/00 , A61P37/00 , C07D471/04
CPC分类号： C07D471/04
摘要： The invention provides 4-{[1-(aminocarbonyl)-4-piperidinyl]amino}-N-[(3,4-dimethylphenyl)methyl]-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide, which is the compound of formula (I): or a salt thereof.
摘要翻译： 本发明提供4 - {[1-（氨基羰基）-4-哌啶基]氨基} -N - [（3,4-二甲基苯基）甲基] -1-乙基-1H-吡唑并[3,4-b]吡啶-5 甲酰胺，其为式（I）的化合物或其盐。
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4.发明授权1,2,3-triazole derivatives for use as stearoyl-CoA desaturase inhibitors 有权用作硬脂酰辅酶A去饱和酶抑制剂的1,2,3-三唑衍生物公开(公告)号：US08486977B2
公开(公告)日：2013-07-16
申请号：US12741637
申请日：2008-11-07
IPC分类号： A61K31/4192 , C07D249/04
CPC分类号： C07D249/04 , C07D413/12
摘要： The present invention relates to substituted triazole compounds of the formula (I): and pharmaceutically acceptable salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds for modulating SCD activity.
摘要翻译： 本发明涉及含有它们的药物组合物及其在药物中的用途的式（I）的取代三唑化合物及其药学上可接受的盐。 特别地，本发明涉及用于调节SCD活性的化合物。
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5.发明申请公开(公告)号：US20060159648A1
公开(公告)日：2006-07-20
申请号：US10545773
申请日：2004-02-13
申请人： Adrian Davis , Lionel Trottet
发明人： Adrian Davis , Lionel Trottet
CPC分类号： A61K47/10 , A61K9/0014 , A61K31/4439 , A61K47/02 , A61K47/24
摘要： There is provided a method for treating a skin condition selected from the list consisting of psoriasis, atopic dermatitis, facial acne, rosacea, photoageing of the face, photoageing of the hands and skin cancer which comprises administering topically to the skin of a patient in need of treatment a pharmaceutical composition containing a drug substance which is a PPAR gamma agonist. There are also provided pharmaceutical compositions and uses thereof.
摘要翻译： 提供了一种治疗皮肤病症的方法，所述病症选自牛皮癣，特应性皮炎，面部痤疮，酒渣鼻，脸部光老化，手和皮肤癌的光老化，其包括局部地给予需要的患者的皮肤 的药物组合物，其含有作为PPARγ激动剂的药物物质。 还提供了药物组合物及其用途。
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6.发明申请公开(公告)号：US20060142356A1
公开(公告)日：2006-06-29
申请号：US10545772
申请日：2004-02-13
申请人： Adrian Davis , Lionel Trottet , Tadataka Yamada
发明人： Adrian Davis , Lionel Trottet , Tadataka Yamada
IPC分类号： A61K31/426
CPC分类号： A61K31/426
摘要： According to the invention there is provided a pharmaceutical composition suitable for topical administration to the skin which comprises farglitazar, or a pharmaceutically acceptable salt thereof, and a physiologically acceptable carrier and its use in the treatment of skin conditions.
摘要翻译： 根据本发明，提供了适用于局部给予皮肤的药物组合物，其包含法格列扎或其药学上可接受的盐，以及生理上可接受的载体及其在治疗皮肤病症中的用途。
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