公开(公告)号：US08818472B2

公开(公告)日：2014-08-26

申请号：US12679721

申请日：2008-09-29

申请人： Dietrich Gravenstein ,  Mark Rice ,  Samsun Lampotang ,  Nikolaus Gravenstein ,  Lori Deitte

发明人： Dietrich Gravenstein ,  Mark Rice ,  Samsun Lampotang ,  Nikolaus Gravenstein ,  Lori Deitte

IPC分类号： A61B5/00

CPC分类号： A61B8/06 ,  A61B5/14552

摘要： Various embodiments of the present invention include devices for use in determining the concentration of a tissue energy absorber (e.g., hemoglobin) in an individual's blood. In particular embodiments, the device includes a photometric device (e.g., a pulse oximeter) and an imaging device (e.g., an ultrasound imaging device or other suitable imaging device), and the device is adapted for: (A) using the photometric device to measure a change in mass of the tissue energy absorber within a particular volume of the individual's blood between a first point in time and a second point in time, the particular volume of blood being blood within a particular portion of at least one vascular structure, the vascular structure comprising at least one of the individual's vessels (e.g., at least one of the individual's arteries); (B) using an ultrasound imaging device to measure a change in interior volume, between the first point in time and the second point in time, of the particular portion of the vascular structure; and (C) using both the measured change in the mass of the tissue energy absorber, and the measured change in interior volume to determine at least an approximate blood total concentration of the tissue energy absorber within the individual's blood.

摘要翻译： 本发明的各种实施方案包括用于确定个体血液中的组织能量吸收剂（例如，血红蛋白）的浓度的装置。 在特定实施例中，该装置包括测光装置（例如，脉搏血氧计）和成像装置（例如，超声成像装置或其它合适的成像装置），并且该装置适于：（A）使用光度装置 测量在第一时间点和第二时间点之间的个体血液的特定体积内的组织能量吸收器的质量变化，血液的特定体积是至少一个血管结构的特定部分内的血液， 血管结构包括个体血管中的至少一个（例如，个体动脉中的至少一个）; （B）使用超声成像装置来测量血管结构的特定部分的第一时间点和第二时间点之间的内部体积的变化; 和（C）使用所测量的组织能量吸收器的质量的变化和所测量的内部体积的变化来确定个体血液内的组织能量吸收器的至少近似血液总浓度。

公开(公告)号：US20100286515A1

公开(公告)日：2010-11-11

申请号：US12679721

申请日：2008-09-29

申请人： Dietrich Gravenstein ,  Mark Rice ,  Sanisun Lanipotang ,  Nikolaus Gravenstein ,  Lori Deitte

发明人： Dietrich Gravenstein ,  Mark Rice ,  Sanisun Lanipotang ,  Nikolaus Gravenstein ,  Lori Deitte

IPC分类号： A61B8/00

CPC分类号： A61B8/06 ,  A61B5/14552

摘要： Various embodiments of the present invention include devices for use in determining the concentration of a tissue energy absorber (e.g., hemoglobin) in an individual's blood. In particular embodiments, the device includes a photometric device (e.g., a pulse oximeter) and an imaging device (e.g., an ultrasound imaging device or other suitable imaging device), and the device is adapted for: (A) using the photometric device to measure a change in mass of the tissue energy absorber within a particular volume of the individual's blood between a first point in time and a second point in time, the particular volume of blood being blood within a particular portion of at least one vascular structure, the vascular structure comprising at least one of the individual's vessels (e.g., at least one of the individual's arteries); (B) using an ultrasound imaging device to measure a change in interior volume, between the first point in time and the second point in time, of the particular portion of the vascular structure; and (C) using both the measured change in the mass of the tissue energy absorber, and the measured change in interior volume to determine at least an approximate blood total concentration of the tissue energy absorber within the individual's blood.

摘要翻译： 本发明的各种实施方案包括用于确定个体血液中的组织能量吸收剂（例如，血红蛋白）的浓度的装置。 在特定实施例中，该装置包括测光装置（例如，脉搏血氧计）和成像装置（例如，超声成像装置或其它合适的成像装置），并且该装置适于：（A）使用光度装置 测量在第一时间点和第二时间点之间的个体血液的特定体积内的组织能量吸收器的质量变化，血液的特定体积是至少一个血管结构的特定部分内的血液， 血管结构包括个体血管中的至少一个（例如，个体动脉中的至少一个）; （B）使用超声成像装置来测量血管结构的特定部分的第一时间点和第二时间点之间的内部体积的变化; 和（C）使用所测量的组织能量吸收器的质量的变化和所测量的内部体积的变化来确定个体血液内的组织能量吸收器的至少近似血液总浓度。