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    Methods and devices for noninvasive measurement of energy absorbers in blood
    1.
    发明授权
    Methods and devices for noninvasive measurement of energy absorbers in blood 有权
    用于无创测量血液中能量吸收器的方法和装置

    公开(公告)号：US08818472B2

    公开(公告)日：2014-08-26

    申请号：US12679721

    申请日：2008-09-29

    申请人： Dietrich Gravenstein ,  Mark Rice ,  Samsun Lampotang ,  Nikolaus Gravenstein ,  Lori Deitte

    发明人： Dietrich Gravenstein ,  Mark Rice ,  Samsun Lampotang ,  Nikolaus Gravenstein ,  Lori Deitte

    IPC分类号： A61B5/00

    CPC分类号： A61B8/06 ,  A61B5/14552

    摘要： Various embodiments of the present invention include devices for use in determining the concentration of a tissue energy absorber (e.g., hemoglobin) in an individual's blood. In particular embodiments, the device includes a photometric device (e.g., a pulse oximeter) and an imaging device (e.g., an ultrasound imaging device or other suitable imaging device), and the device is adapted for: (A) using the photometric device to measure a change in mass of the tissue energy absorber within a particular volume of the individual's blood between a first point in time and a second point in time, the particular volume of blood being blood within a particular portion of at least one vascular structure, the vascular structure comprising at least one of the individual's vessels (e.g., at least one of the individual's arteries); (B) using an ultrasound imaging device to measure a change in interior volume, between the first point in time and the second point in time, of the particular portion of the vascular structure; and (C) using both the measured change in the mass of the tissue energy absorber, and the measured change in interior volume to determine at least an approximate blood total concentration of the tissue energy absorber within the individual's blood.

    摘要翻译： 本发明的各种实施方案包括用于确定个体血液中的组织能量吸收剂（例如，血红蛋白）的浓度的装置。 在特定实施例中，该装置包括测光装置（例如，脉搏血氧计）和成像装置（例如，超声成像装置或其它合适的成像装置），并且该装置适于：（A）使用光度装置 测量在第一时间点和第二时间点之间的个体血液的特定体积内的组织能量吸收器的质量变化，血液的特定体积是至少一个血管结构的特定部分内的血液， 血管结构包括个体血管中的至少一个（例如，个体动脉中的至少一个）; （B）使用超声成像装置来测量血管结构的特定部分的第一时间点和第二时间点之间的内部体积的变化; 和（C）使用所测量的组织能量吸收器的质量的变化和所测量的内部体积的变化来确定个体血液内的组织能量吸收器的至少近似血液总浓度。

    Novel Methods and Devices for Noninvasive Measurement of Energy Absorbers in Blood
    2.
    发明申请
    Novel Methods and Devices for Noninvasive Measurement of Energy Absorbers in Blood 有权
    用于无创测量血液中能量吸收器的新方法和设备

    公开(公告)号：US20100286515A1

    公开(公告)日：2010-11-11

    申请号：US12679721

    申请日：2008-09-29

    申请人： Dietrich Gravenstein ,  Mark Rice ,  Sanisun Lanipotang ,  Nikolaus Gravenstein ,  Lori Deitte

    发明人： Dietrich Gravenstein ,  Mark Rice ,  Sanisun Lanipotang ,  Nikolaus Gravenstein ,  Lori Deitte

    IPC分类号： A61B8/00

    CPC分类号： A61B8/06 ,  A61B5/14552

    摘要： Various embodiments of the present invention include devices for use in determining the concentration of a tissue energy absorber (e.g., hemoglobin) in an individual's blood. In particular embodiments, the device includes a photometric device (e.g., a pulse oximeter) and an imaging device (e.g., an ultrasound imaging device or other suitable imaging device), and the device is adapted for: (A) using the photometric device to measure a change in mass of the tissue energy absorber within a particular volume of the individual's blood between a first point in time and a second point in time, the particular volume of blood being blood within a particular portion of at least one vascular structure, the vascular structure comprising at least one of the individual's vessels (e.g., at least one of the individual's arteries); (B) using an ultrasound imaging device to measure a change in interior volume, between the first point in time and the second point in time, of the particular portion of the vascular structure; and (C) using both the measured change in the mass of the tissue energy absorber, and the measured change in interior volume to determine at least an approximate blood total concentration of the tissue energy absorber within the individual's blood.

    摘要翻译： 本发明的各种实施方案包括用于确定个体血液中的组织能量吸收剂（例如，血红蛋白）的浓度的装置。 在特定实施例中，该装置包括测光装置（例如，脉搏血氧计）和成像装置（例如，超声成像装置或其它合适的成像装置），并且该装置适于：（A）使用光度装置 测量在第一时间点和第二时间点之间的个体血液的特定体积内的组织能量吸收器的质量变化，血液的特定体积是至少一个血管结构的特定部分内的血液， 血管结构包括个体血管中的至少一个（例如，个体动脉中的至少一个）; （B）使用超声成像装置来测量血管结构的特定部分的第一时间点和第二时间点之间的内部体积的变化; 和（C）使用所测量的组织能量吸收器的质量的变化和所测量的内部体积的变化来确定个体血液内的组织能量吸收器的至少近似血液总浓度。

    Pilot symbols in communication systems
    5.
    发明授权
    Pilot symbols in communication systems 有权
    通信系统中的导频符号

    公开(公告)号：US07558354B2

    公开(公告)日：2009-07-07

    申请号：US10522566

    申请日：2003-11-07

    申请人： Michael Robert Peake ,  Mark Rice

    发明人： Michael Robert Peake ,  Mark Rice

    IPC分类号： H04L7/00

    CPC分类号： H04B1/76 ,  H04L25/0226 ,  H04L2027/0097

    摘要： This invention relates to signal processing in telecommunications, particularly but not exclusively for use in wireless TDMA systems. In particular, the invention concerns methods for use in communication systems making use of pilot symbols. The invention provides a method of placing pilot symbols in a data stream for telecommunication systems, wherein the pilot symbols are spaced in time using a range of different intervals between symbols. The intervals between the pilot symbols are substantially fractal in nature, the distribution of pilot symbols involving repetitions of irregular groupings of pilot symbols in the data stream. Preferably, the irregular groupings of pilot symbols are irregularly spaced in the data stream. The invention also provides a method and means for acquiring the time and frequency offset of a packet of data by using pilot symbols distributed within the packet as defined above.

    摘要翻译： 本发明涉及电信中的信号处理，特别地但不排他地用于无线TDMA系统。 特别地，本发明涉及在使用导频符号的通信系统中使用的方法。 本发明提供了一种将导频符号放置在电信系统的数据流中的方法，其中导频符号使用符号之间的不同间隔的范围在时间上间隔开。 导频符号之间的间隔本质上基本上是分形的，导频符号的分布涉及数据流中导频符号的不规则分组的重复。 优选地，导频符号的不规则分组在数据流中不规则地间隔开。 本发明还提供一种用于通过使用如上所述在分组内分发的导频符号来获取数据分组的时间和频率偏移的方法和装置。

    SPINAL STABILIZATION SYSTEM WITH FLEXIBLE GUIDES
    6.
    发明申请
    SPINAL STABILIZATION SYSTEM WITH FLEXIBLE GUIDES 有权
    具有灵活指导的脊柱稳定系统

    公开(公告)号：US20080161857A1

    公开(公告)日：2008-07-03

    申请号：US11539287

    申请日：2006-10-06

    申请人： Hugh Hestad ,  Mark Rice

    发明人： Hugh Hestad ,  Mark Rice

    IPC分类号： A61B17/70

    CPC分类号： A61B17/025 ,  A61B17/7031 ,  A61B17/7032 ,  A61B17/7085 ,  A61B2017/0256

    摘要： In one embodiment, a spinal stabilization apparatus includes a vertebral anchor having a head portion and a bone attachment portion. An elongate, flexible guide is removably coupled to the head portion of the vertebral anchor and has a channel extending longitudinally thereof and communicating with a slot in the head portion of the anchor. An elongate cord may be received within the channel to facilitate inserting and securing a spacer between pairs of anchors installed into adjacent vertebrae of a person's spine.

    摘要翻译： 在一个实施例中，脊柱稳定装置包括具有头部部分和骨骼附接部分的椎骨锚固件。 细长的柔性引导件可移除地联接到椎骨锚固件的头部，并且具有沿其纵向延伸并与锚固件的头部中的狭槽连通的通道。 细长的绳索可以容纳在通道内，以便于在安装到人的脊椎的相邻椎骨中的锚定体对之间插入和固定间隔物。

    Intraocular lens measurement of blood glucose
    7.
    发明申请
    Intraocular lens measurement of blood glucose 审中-公开
    人工晶状体测量血糖

    公开(公告)号：US20060183986A1

    公开(公告)日：2006-08-17

    申请号：US11057080

    申请日：2005-02-11

    申请人： Mark Rice ,  John Smith

    发明人： Mark Rice ,  John Smith

    IPC分类号： A61B5/00

    CPC分类号： A61B5/1459 ,  A61B5/14532

    摘要： One aspect of the invention provides a blood glucose monitoring system including a light source adapted to transmit light onto at least a portion of a retina of an eye of a subject; a sensor adapted to receive light from the retina; a data capture and analysis system adapted to calculate blood glucose concentration of the subject from the light received by the sensor; and support structure adapted to maintain positions of the light source and the sensor; wherein at least one of the light source and the sensor is further adapted to be implanted within the eye. Another aspect of the invention provides a method of determining blood glucose concentration of a subject including the steps of: transmitting light to a retina of an eye of the subject; receiving reflected light from the retina; and calculating blood glucose concentration from the reflected light, wherein one or both of the light source and sensor are disposed within the eye. The invention also provides a method of implanting a blood glucose monitor as well as a blood glucose monitor adapted to receive information from a sensor disposed within a subject's eye.

    摘要翻译： 本发明的一个方面提供一种血糖监测系统，其包括适于将光线透射到被检体的眼睛的视网膜的至少一部分上的光源; 适于接收来自视网膜的光的传感器; 数据采集​​和分析系统，适于根据由传感器接收的光计算受试者的血糖浓度; 以及适于保持光源和传感器的位置的支撑结构; 其中光源和传感器中的至少一个还适于植入眼睛内。 本发明的另一方面提供了一种测定对象的血糖浓度的方法，包括以下步骤：将光传送到对象的眼睛的视网膜; 接收来自视网膜的反射光; 以及从所述反射光计算血糖浓度，其中所述光源和传感器中的一个或两个设置在所述眼睛内。 本发明还提供了一种植入血糖监测器的方法以及适于从设置在受试者眼睛内的传感器接收信息的血糖监测器。

    Non-invasive measurement of blood analytes using photodynamics
    9.
    发明申请
    Non-invasive measurement of blood analytes using photodynamics 审中-公开

    公开(公告)号：US20050101847A1

    公开(公告)日：2005-05-12

    申请号：US11005767

    申请日：2004-12-06

    申请人： Wilson Routt ,  Mark Rice

    发明人： Wilson Routt ,  Mark Rice

    IPC分类号： A61B3/12 ,  A61B5/00

    CPC分类号： A61B5/1455 ,  A61B3/12 ,  A61B5/14532 ,  A61B5/14558

    摘要： The determination of blood glucose in an individual is carried out by projecting illuminating light into an eye of the individual to illuminate the retina with the light having wavelengths that are absorbed by rhodopsin and with the intensity of the light varying in a prescribed temporal manner. The light reflected from the retina is detected to provide a signal corresponding to the intensity of the detected light, and the detected light signal is analyzed to determine the changes in form from that of the illuminating light. For a biased sinusoidal illumination, these changes can be expressed in terms of harmonic content of the detected light. The changes in form of the detected light are related to the ability of rhodopsin to absorb light and regenerate, which in turn is related to the concentration of blood glucose, allowing a determination of the relative concentration of blood glucose. Other photoreactive analytes can similarly be determined by projecting time varying illuminating light into the eye, detecting the light reflected from the retina, and analyzing the detected light signal to determine changes in form of the signal due to changes in absorptivity of a photoreactive analyte.

    Method and receiver for processing a multi-user signal
    10.
    发明授权
    Method and receiver for processing a multi-user signal 有权
    用于处理多用户信号的方法和接收器

    公开(公告)号：US07415001B2

    公开(公告)日：2008-08-19

    申请号：US10510473

    申请日：2003-06-13

    申请人： Sanjeev Naguleswaran ,  Mark Rice

    发明人： Sanjeev Naguleswaran ,  Mark Rice

    IPC分类号： H04B7/212 ,  H04J3/00 ,  H04Q7/20 ,  H04L5/14 ,  H04Q7/00 ,  H04Q7/28 ,  H04B1/16 ,  H04B1/00 ,  H04L5/12 ,  H03D1/00

    CPC分类号： H04B1/71075 ,  H04B1/10 ,  H04B1/7103 ,  H04L1/0048 ,  H04L1/0051 ,  H04L1/0054 ,  H04L1/0066 ,  H04L25/0206 ,  H04L25/067

    摘要： The invention relates to the field of signal processing for telecommunications, and concerns a method and receiver for processing a multi-user signal. In the method of the invention, a multi-user signal is processed by a receiver using an iterative receiver process including the steps of (a) receiving a signal transmission including a plurality of user signals on a TDMA channel, (b) detecting one or more user signals and determining transmission channel estimates for each said user signal, (c) deriving a soft signal for a first user by subtracting, if available, weighted representations of other user signals from the detected user signal of said first user, (d) calculating a-posteriori probabilities for each symbol comprising the soft signal, (e) refining said probabilities utilizing the transmission channel estimate for the first user in an iterative decoding algorithm, wherein a probability is either partially or fully decoded depending on the application of decoder convergence criteria, and (f) returning to step (a), (b) or (c) with the refined probabilities forming part of the weighted representations to be subtracted from detected user signals of other users. This method allows for efficient detection and decoding of multiple user signals by controlling the behaviour of an iterative decoding algorithm operating within an iterative receiver process.

    摘要翻译： 本发明涉及用于电信的信号处理领域，涉及用于处理多用户信号的方法和接收机。 在本发明的方法中，多用户信号由接收机使用迭代接收机处理，包括以下步骤：（a）在TDMA信道上接收包括多个用户信号的信号传输，（b）检测一个或 （c）通过从所检测的所述第一用户的用户信号中减去其他用户信号的加权表示（如果可用的话），导出用于第一用户的软信号，（d） 计算包括所述软信号的每个符号的后验概率，（e）利用迭代解码算法中的第一用户的传输信道估计来精简所述概率，其中根据解码器收敛的应用，概率被部分地或完全地解码 标准，以及（f）返回到步骤（a），（b）或（c），其中形成的部分加权表示的精确概率被从检测中减去 其他用户的用户信号。 该方法允许通过控制在迭代接收器过程中操作的迭代解码算法的行为来有效地检测和解码多个用户信号。