公开(公告)号：US20100286515A1

公开(公告)日：2010-11-11

申请号：US12679721

申请日：2008-09-29

申请人： Dietrich Gravenstein ,  Mark Rice ,  Sanisun Lanipotang ,  Nikolaus Gravenstein ,  Lori Deitte

发明人： Dietrich Gravenstein ,  Mark Rice ,  Sanisun Lanipotang ,  Nikolaus Gravenstein ,  Lori Deitte

IPC分类号： A61B8/00

CPC分类号： A61B8/06 ,  A61B5/14552

摘要： Various embodiments of the present invention include devices for use in determining the concentration of a tissue energy absorber (e.g., hemoglobin) in an individual's blood. In particular embodiments, the device includes a photometric device (e.g., a pulse oximeter) and an imaging device (e.g., an ultrasound imaging device or other suitable imaging device), and the device is adapted for: (A) using the photometric device to measure a change in mass of the tissue energy absorber within a particular volume of the individual's blood between a first point in time and a second point in time, the particular volume of blood being blood within a particular portion of at least one vascular structure, the vascular structure comprising at least one of the individual's vessels (e.g., at least one of the individual's arteries); (B) using an ultrasound imaging device to measure a change in interior volume, between the first point in time and the second point in time, of the particular portion of the vascular structure; and (C) using both the measured change in the mass of the tissue energy absorber, and the measured change in interior volume to determine at least an approximate blood total concentration of the tissue energy absorber within the individual's blood.

摘要翻译： 本发明的各种实施方案包括用于确定个体血液中的组织能量吸收剂（例如，血红蛋白）的浓度的装置。 在特定实施例中，该装置包括测光装置（例如，脉搏血氧计）和成像装置（例如，超声成像装置或其它合适的成像装置），并且该装置适于：（A）使用光度装置 测量在第一时间点和第二时间点之间的个体血液的特定体积内的组织能量吸收器的质量变化，血液的特定体积是至少一个血管结构的特定部分内的血液， 血管结构包括个体血管中的至少一个（例如，个体动脉中的至少一个）; （B）使用超声成像装置来测量血管结构的特定部分的第一时间点和第二时间点之间的内部体积的变化; 和（C）使用所测量的组织能量吸收器的质量的变化和所测量的内部体积的变化来确定个体血液内的组织能量吸收器的至少近似血液总浓度。

公开(公告)号：US08818472B2

公开(公告)日：2014-08-26

申请号：US12679721

申请日：2008-09-29

申请人： Dietrich Gravenstein ,  Mark Rice ,  Samsun Lampotang ,  Nikolaus Gravenstein ,  Lori Deitte

发明人： Dietrich Gravenstein ,  Mark Rice ,  Samsun Lampotang ,  Nikolaus Gravenstein ,  Lori Deitte

IPC分类号： A61B5/00

CPC分类号： A61B8/06 ,  A61B5/14552

摘要： Various embodiments of the present invention include devices for use in determining the concentration of a tissue energy absorber (e.g., hemoglobin) in an individual's blood. In particular embodiments, the device includes a photometric device (e.g., a pulse oximeter) and an imaging device (e.g., an ultrasound imaging device or other suitable imaging device), and the device is adapted for: (A) using the photometric device to measure a change in mass of the tissue energy absorber within a particular volume of the individual's blood between a first point in time and a second point in time, the particular volume of blood being blood within a particular portion of at least one vascular structure, the vascular structure comprising at least one of the individual's vessels (e.g., at least one of the individual's arteries); (B) using an ultrasound imaging device to measure a change in interior volume, between the first point in time and the second point in time, of the particular portion of the vascular structure; and (C) using both the measured change in the mass of the tissue energy absorber, and the measured change in interior volume to determine at least an approximate blood total concentration of the tissue energy absorber within the individual's blood.

摘要翻译： 本发明的各种实施方案包括用于确定个体血液中的组织能量吸收剂（例如，血红蛋白）的浓度的装置。 在特定实施例中，该装置包括测光装置（例如，脉搏血氧计）和成像装置（例如，超声成像装置或其它合适的成像装置），并且该装置适于：（A）使用光度装置 测量在第一时间点和第二时间点之间的个体血液的特定体积内的组织能量吸收器的质量变化，血液的特定体积是至少一个血管结构的特定部分内的血液， 血管结构包括个体血管中的至少一个（例如，个体动脉中的至少一个）; （B）使用超声成像装置来测量血管结构的特定部分的第一时间点和第二时间点之间的内部体积的变化; 和（C）使用所测量的组织能量吸收器的质量的变化和所测量的内部体积的变化来确定个体血液内的组织能量吸收器的至少近似血液总浓度。

公开(公告)号：US6161537A

公开(公告)日：2000-12-19

申请号：US451811

申请日：1995-05-26

申请人： Dietrich Gravenstein ,  Nikolaus Gravenstein ,  Richard J. Melker ,  Samsun Lampotang ,  Anwer Sultan

发明人： Dietrich Gravenstein ,  Nikolaus Gravenstein ,  Richard J. Melker ,  Samsun Lampotang ,  Anwer Sultan

IPC分类号： A61M16/04 ,  A61M16/00

CPC分类号： A61M16/0488 ,  A61B5/0059 ,  A61B5/061

摘要： An intubation scope assembly adapted to facilitate the positioning of an endotracheal tube in a patient comprising an electromagnetic or sound energy source which enters the vocal cords exteriorly of the neck of the patient with energy having a direction, wavelength and intensity capable of entering the trachea, substantially avoiding encompassing the entire pharynx and capable of being transmitted cephalad substantially between and/or around the vocal cords. A suitable sensor for the energy emitted by such source comprises a stylet assembly, the distal end of which can detect or collect the energy transmitted between and/or around the vocal cords and the proximal end of which can monitor the detected or collected energy to thereby locate the vocal cords for positioning an endotracheal tube therebetween. A system and method of intubating a patient with the foregoing assembly are also disclosed.

摘要翻译： 一种适于促进气管插管在患者中的定位的插管范围组件，包括电磁或声能量源，其以能够进入气管的方向，波长和强度的能量进入患者颈部外部的声带， 基本上避免包围整个咽部并且能够基本上在声带之间和/或周围传播头脑。 用于由这种源发射的能量的合适的传感器包括探针组件，该探针组件的远端可以检测或收集在声带之间和/或周围传播的能量，其近端可以监测所检测或收集的能量，从而 找到用于将气管内管置于其间的声带。 还公开了将患者插入前述组件的系统和方法。

公开(公告)号：US5560351A

公开(公告)日：1996-10-01

申请号：US319543

申请日：1994-10-07

申请人： Dietrich Gravenstein ,  Nikolaus Gravenstein ,  Richard J. Melker ,  Samsun Lampotang ,  Anwer Sultan

发明人： Dietrich Gravenstein ,  Nikolaus Gravenstein ,  Richard J. Melker ,  Samsun Lampotang ,  Anwer Sultan

IPC分类号： A61M16/04

CPC分类号： A61M16/0488 ,  A61B5/0059 ,  A61B5/061

摘要： An intubation scope assembly adapted to facilitate the positioning of an endotracheal tube in a patient comprising an electromagnetic or sound energy source which enters the vocal cords exteriorly of the neck of the patient with energy having a direction, wavelength and intensity capable of entering the trachea, substantially avoiding encompassing the entire pharynx and capable of being transmitted cephalad substantially between and/or around the vocal cords. A suitable sensor for the energy emitted by such source comprises a stylet assembly, the distal end of which can detect or collect the energy transmitted between and/or around the vocal cords and the proximal end of which can monitor the detected or collected energy to thereby locate the vocal cords for positioning an endotracheal tube therebetween. A system and method of intubating a patient with the foregoing assembly are also disclosed.

公开(公告)号：US5101825A

公开(公告)日：1992-04-07

申请号：US368636

申请日：1989-06-20

申请人： Dietrich Gravenstein ,  J. E. W. Beneken ,  Samsun Lampotang ,  Nikolaus Gravenstein ,  Michael A. Brooks ,  Gordon L. Gibby ,  Robert J. Atwater

发明人： Dietrich Gravenstein ,  J. E. W. Beneken ,  Samsun Lampotang ,  Nikolaus Gravenstein ,  Michael A. Brooks ,  Gordon L. Gibby ,  Robert J. Atwater

IPC分类号： A61B5/00

CPC分类号： A61B5/14551 ,  A61B5/14535 ,  A61B5/417

摘要： Described here are a novel means and device for noninvasively quantifying important blood constituents. Total hemoglobin, arterial oxygen content, hematocrit, and other parameters can all be determined quickly and easily without the need for skin puncture or lengthy laboratory analysis. The invention described here concerns the simultaneous measurement of volume changes and changes in the mass of either oxyhemoglobin, total hemoglobin, or reduced hemoglobin. The data obtained by these measurements is used to quantify the parameters of interest.

摘要翻译： 这里描述的是用于非侵入性地量化重要血液成分的新颖手段和装置。 总体血红蛋白，动脉氧含量，血细胞比容等参数都可以快速，容易地确定，无需皮肤穿刺或长时间的实验室分析。 这里描述的发明涉及同时测量体积变化和氧合血红蛋白，总血红蛋白或还原血红蛋白质量的变化。 通过这些测量获得的数据用于量化感兴趣的参数。

公开(公告)号：US4928687A

公开(公告)日：1990-05-29

申请号：US255400

申请日：1988-10-11

申请人： Samsun Lampotang ,  Dietrich Gravenstein ,  Joachim S. Gravenstein ,  Nikolaus Gravenstein ,  Michael J. Banner

发明人： Samsun Lampotang ,  Dietrich Gravenstein ,  Joachim S. Gravenstein ,  Nikolaus Gravenstein ,  Michael J. Banner

IPC分类号： A61M16/04

CPC分类号： A61M16/0488 ,  A61M2016/0413

摘要： A diagnostic monitor checks the carbon dioxide (CO.sub.2) content of a gas exiting a patient during endotracheal or esophageal intubation. A plurality of composition portions substantially change color in response to exposure to the carbon dioxide. The composition portions change color in response to different times of exposure to carbon dioxide. A magnifying or condensing lens may be positioned on the monitor to enhance viewing of the color change. The monitor may advantageously be made as part of an intubation system through which the gases from a patient exit the patient. The differences in time of exposure needed to cause the color change may be accomplished by using semipermeable membranes having differing thicknesses, CO.sub.2 permeabilities, and/or surface areas with each membrane corresponding to a particular one of the composition portions.

摘要翻译： 诊断监测器检查在气管插管或食管插管期间离开患者的气体的二氧化碳（CO2）含量。 多个组合物部分基于暴露于二氧化碳而显着改变颜色。 组合物部分响应于暴露于二氧化碳的不同时间而改变颜色。 可以将放大或聚光透镜放置在监视器上以增强对颜色变化的观察。 可以有利地将监测器制成为插管系统的一部分，来自患者的气体通过该插管系统离开患者。 导致颜色变化所需的曝光时间差异可以通过使用具有不同厚度的半透膜，CO 2渗透性和/或表面积来实现，其中每个膜对应于组合物部分的特定一个。

公开(公告)号：US5156159A

公开(公告)日：1992-10-20

申请号：US505689

申请日：1990-04-09

申请人： Samsun Lampotang ,  Joachim S. Gravenstein ,  Nikolaus Gravenstein ,  Michael J. Banner ,  Dietrich Gravenstein

发明人： Samsun Lampotang ,  Joachim S. Gravenstein ,  Nikolaus Gravenstein ,  Michael J. Banner ,  Dietrich Gravenstein

IPC分类号： A61M16/04

CPC分类号： A61M16/0488 ,  A61M2016/0413

摘要： A diagnostic monitor checks the carbon dioxide (CO.sub.2) content of a gas exiting a patient during endotracheal or esophageal intubation. A plurality of composition portions substantially change color in response to exposure to the carbon dioxide. The composition portions change color in response to different times of exposure to carbon dioxide. A magnifying or condensing lens may be positioned on the monitor to enhance viewing of the color change. The monitor may advantageously be made part of an intubation system through which the gases from a patient exit the patient. The differences in time of exposure needed to cause the color change may be accomplished by using semipermeable membranes having differing thicknesses, CO.sub.2 permeabilities, and/or surface areas with each membrane corresponding to a particular one of the composition portions. An arrangement is provided whereby the monitor is automatically activated by the normal assembly steps of a patient breathing circuit.

摘要翻译： 诊断监测器检查在气管插管或食管插管期间离开患者的气体的二氧化碳（CO2）含量。 多个组合物部分基于暴露于二氧化碳而显着改变颜色。 组合物部分响应于暴露于二氧化碳的不同时间而改变颜色。 可以将放大或聚光透镜放置在监视器上以增强对颜色变化的观察。 可以有利地将监护仪制成插管系统的一部分，来自患者的气体通过该插管系统离开患者。 导致颜色变化所需的曝光时间差异可以通过使用具有不同厚度的半透膜，CO 2渗透性和/或表面积来实现，其中每个膜对应于组合物部分的特定一个。 提供了一种布置，由此通过患者呼吸回路的正常组装步骤自动启动监视器。

公开(公告)号：US09962516B2

公开(公告)日：2018-05-08

申请号：US13821611

申请日：2011-09-08

申请人： Samsun Lampotang ,  Nikolaus Gravenstein ,  Wilhelm K. Schwab ,  David E. Lizdas ,  Francesca K. Enneking

发明人： Samsun Lampotang ,  Nikolaus Gravenstein ,  Wilhelm K. Schwab ,  David E. Lizdas ,  Francesca K. Enneking

IPC分类号： A61M5/00 ,  A61M25/00 ,  A61M1/00 ,  A61M39/08 ,  A61M39/28 ,  A61M31/00 ,  A61M25/16 ,  A61M27/00

CPC分类号： A61M25/0017 ,  A61M1/0021 ,  A61M39/08 ,  A61M39/28 ,  A61M39/284

摘要： Embodiments of the invention provide methods and devices for improved drainage systems and tubing. In one embodiment, a context-sensitive flow interrupter is provided that inhibits or facilitates flow of fluid when engaged with a mating holder. In another embodiment, outflow is optimized through control of the pressure in gas pockets in a tube, drainage tube or assembly. In one such embodiment, gas pockets are vented to inhibit excessive back-pressure or suction on an organ, vessel or cavity being drained. In another such embodiment, loops in the tubes are avoided by using a mechanical template in the form of a groove or peg assembly to thread the slack in the drainage tube to generate a monotonic gradient. In another embodiment, such as for active drainage systems, a bypass channel is provided that allows an applied vacuum to go around an obstruction created by the collection of fluid in an undrained dependent loop.

公开(公告)号：US09251721B2

公开(公告)日：2016-02-02

申请号：US13514474

申请日：2011-04-08

申请人： Samsun Lampotang ,  Nikolaus Gravenstein ,  David Erik Lizdas ,  Isaac Thomas Luria ,  Matthew James Peterson

发明人： Samsun Lampotang ,  Nikolaus Gravenstein ,  David Erik Lizdas ,  Isaac Thomas Luria ,  Matthew James Peterson

IPC分类号： G06T19/00 ,  G09B23/28

CPC分类号： G06T19/006 ,  B33Y80/00 ,  G06F3/011 ,  G06F3/017 ,  G06F3/02 ,  G06T7/20 ,  G06T7/70 ,  G06T19/20 ,  G06T2207/10028 ,  G09B9/00 ,  G09B23/28 ,  G09B23/285 ,  G09B23/286 ,  G09B23/30

摘要： An interactive mixed reality simulator is provided that includes a virtual 3D model of internal or hidden features of an object; a physical model or object being interacted with; and a tracked instrument used to interact with the physical object. The tracked instrument can be used to simulate or visualize interactions with internal features of the physical object represented by the physical model. In certain embodiments, one or more of the internal features can be present in the physical model. In another embodiment, some internal features do not have a physical presence within the physical model.

摘要翻译： 提供了一种交互式混合现实模拟器，其包括对象的内部或隐藏特征的虚拟3D模型; 与之相互作用的物理模型或物体; 以及用于与物理对象交互的跟踪仪器。 跟踪的仪器可用于模拟或可视化与物理模型表示的物理对象的内部特征的交互。 在某些实施例中，一个或多个内部特征可以存在于物理模型中。 在另一个实施例中，一些内部特征在物理模型中不具有物理存在。

公开(公告)号：US20130172840A1

公开(公告)日：2013-07-04

申请号：US13821611

申请日：2011-09-08

申请人： Samsun Lampotang ,  Nikolaus Gravenstein ,  Wilhelm K. Schwab ,  David E. Lizdas ,  Francesca K. Enneking

发明人： Samsun Lampotang ,  Nikolaus Gravenstein ,  Wilhelm K. Schwab ,  David E. Lizdas ,  Francesca K. Enneking

IPC分类号： A61M25/00

CPC分类号： A61M25/0017 ,  A61M1/0021 ,  A61M39/08 ,  A61M39/28 ,  A61M39/284

摘要： Embodiments of the invention provide methods and devices for improved drainage systems and tubing. In one embodiment, a context-sensitive flow interrupter is provided that inhibits or facilitates flow of fluid when engaged with a mating holder. In another embodiment, outflow is optimized through control of the pressure in gas pockets in a tube, drainage tube or assembly. In one such embodiment, gas pockets are vented to inhibit excessive back-pressure or suction on an organ, vessel or cavity being drained. In another such embodiment, loops in the tubes are avoided by using a mechanical template in the form of a groove or peg assembly to thread the slack in the drainage tube to generate a monotonic gradient. In another embodiment, such as for active drainage systems, a bypass channel is provided that allows an applied vacuum to go around an obstruction created by the collection of fluid in an undrained dependent loop.

摘要翻译： 本发明的实施例提供了用于改进排水系统和管道的方法和装置。 在一个实施例中，提供了上下文相关的流动断续器，其在与配合保持器接合时抑制或促进流体的流动。 在另一个实施例中，通过控制管，引流管或组件中的气穴中的压力来优化流出。 在一个这样的实施例中，气囊被排出以抑制排出的器官，血管或空腔上的过度背压或抽吸。 在另一个这样的实施例中，通过使用凹槽或钉组件的形式的机械模板来避免管中的环线，以将引流管中的松弛线螺纹以产生单调梯度。 在另一个实施例中，例如对于主动排水系统，提供旁路通道，其允许施加的真空绕在由不排水的依赖回路中的流体收集产生的阻塞。