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公开(公告)号：US08883307B2
公开(公告)日：2014-11-11
申请号：US12451667
申请日：2008-05-09
申请人： Jin Satomi , Maki Inaba
发明人： Jin Satomi , Maki Inaba
CPC分类号： A23L1/2364 , A23L27/34 , A23L29/37 , A61K9/145 , A61K47/10 , C07H3/02 , C13B30/02 , Y10T428/2982
摘要： [Summary][Problems] To provide extremely-spherical-three-dimensional-shaped particles of crystalline mannitol containing large hollows and gaps inside.[Solution] Spherical particles of crystalline mannitol made by spray drying, extremely spherical (having an aspect ratio of 1.0 to 1.2), high oil absorption rates according to test method A, wherein powder has a mean particle diameter of 15 to 165 μm, a loose bulk density of 0.35 to 0.60 and an angle of repose of 30 to 50 degrees, and has a hardness of 7 to 20 kgf, when directly compressed.
摘要翻译： [摘要] [问题]提供在其内部含有大的中空和间隙的结晶甘露糖醇的极球形三维形状的颗粒。 [溶液]通过喷雾干燥，极球形（长径比为1.0〜1.2）制造的结晶甘露醇的球状颗粒，根据试验方法A的高吸油率，其中粉末的平均粒径为15〜165μm， 松散堆积密度为0.35〜0.60，休止角为30〜50度，直接压缩时硬度为7〜20kgf。
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公开(公告)号：US20100167052A1
公开(公告)日：2010-07-01
申请号：US12451667
申请日：2008-05-09
申请人： Jin Satomi , Maki Inaba
发明人： Jin Satomi , Maki Inaba
CPC分类号： A23L1/2364 , A23L27/34 , A23L29/37 , A61K9/145 , A61K47/10 , C07H3/02 , C13B30/02 , Y10T428/2982
摘要： [Summary][Problems] To provide extremely-spherical-three-dimensional-shaped particles of crystalline mannitol containing large hollows and gaps inside. [Solution] Spherical particles of crystalline mannitol made by spray drying, extremely spherical (having an aspect ratio of 1.0 to 1.2), high oil absorption rates according to test method A, wherein powder has a mean particle diameter of 15 to 165 μm, a loose bulk density of 0.35 to 0.60 and an angle of repose of 30 to 50 degrees, and has a hardness of 7 to 20 kgf, when directly compressed.
摘要翻译： [摘要] [问题]提供在其内部含有大的中空和间隙的结晶甘露糖醇的极球形三维形状的颗粒。 [溶液]通过喷雾干燥，极球形（长径比为1.0〜1.2）制造的结晶甘露醇的球状颗粒，根据试验方法A的高吸油率，其中粉末的平均粒径为15〜165μm， 松散堆积密度为0.35〜0.60，休止角为30〜50度，直接压缩时硬度为7〜20kgf。
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