公开(公告)号：US5192685A

公开(公告)日：1993-03-09

申请号：US512131

申请日：1990-04-20

申请人： Hisako Yasui ,  Kazuhito Hayakawa ,  Makoto Ohwaki ,  Tatsuhiko Kan

发明人： Hisako Yasui ,  Kazuhito Hayakawa ,  Makoto Ohwaki ,  Tatsuhiko Kan

IPC分类号： G01N33/53 ,  C12N1/20 ,  C12N5/06 ,  C12P21/00 ,  C12R1/01 ,  G01N33/50 ,  G01N33/569 ,  G01N33/68

CPC分类号： G01N33/6854 ,  C12R1/225 ,  G01N33/5047

摘要： The present invention is to provide an easy, rapid method for screening a great amount of substances having IgA induction potential. The IgA induction potential herein mentioned means the potential to activate and enhance the activity of IgA production cells to produce secretory-type IgA in response to antigen. The present invention is to provide bacterial strains of genus Bifidobacterium obtained by the method for screening substances having IgA induction potential. More specifically, the present invention is to provide Bifidobacterium longum YIT 4062, Bifidobacterium breve YIT 4063 and Bifidobacterium breve YIT 4064. The three strains obtained by the present invention have high IgA induction potential.

公开(公告)号：US06461627B1

公开(公告)日：2002-10-08

申请号：US09787928

申请日：2001-04-03

申请人： Minoru Ichioka ,  Toshiro Sone ,  Tomoko Hanamizu ,  Makoto Ohwaki ,  Katsuyoshi Chiba ,  Koji Miyazaki ,  Yoshio Hiraki ,  Satoshi Yoshikawa

发明人： Minoru Ichioka ,  Toshiro Sone ,  Tomoko Hanamizu ,  Makoto Ohwaki ,  Katsuyoshi Chiba ,  Koji Miyazaki ,  Yoshio Hiraki ,  Satoshi Yoshikawa

IPC分类号： A61K600

CPC分类号： A61Q19/08 ,  A61K8/97 ,  A61K8/99 ,  A61K36/48 ,  A61K2800/85

摘要： Skin preparations for external use and cosmetics which contain a fermented soybean extract prepared by extracting with an organic solvent a fermentation product obtained by treating a soybean extract with one or more microorganisms selected from bifidobacteria. These preparations are excellent in the effects of relieving wrinkles and ameliorating rough skin.

摘要翻译： 含有发酵大豆提取物的皮肤制剂，其通过用有机溶剂萃取通过用选自双歧杆菌的一种或多种微生物处理大豆提取物获得的发酵产物而制备的。 这些制剂在缓解皱纹和改善粗糙皮肤的效果方面表现优异。