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公开(公告)号：US5032509A
公开(公告)日：1991-07-16
申请号：US416459
申请日：1989-10-03
摘要： A method of preparing a mixture of galactooligosaccharides having the following formula:Gal-(Gal)n-Glcwhere Gal represents a galactose residue, Glc represents a glucose residue, and n represents an integer between 1 and 4, and monosaccharides by having microorganisms containing .beta.-galactosidase or .beta.-galactosidase act on lactose, the method comprising:having glucose isomerase coexist in a liquid to be reacted or adding glucose isomerase after completion of the reaction, whereby a portion of glucose prepared by the .beta.-galactosidase processing is converted into fructose. Then, sweetener is prepared by separating monosaccharides from the mixture.
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公开(公告)号：US07582305B2
公开(公告)日：2009-09-01
申请号：US11522161
申请日：2006-09-15
申请人： Kazunari Ushida , Takamitsu Tsukahara , Wakoto Bukawa , Tatsuhiko Kan , Takumi Watanabe , Noritaka Matsubara
发明人： Kazunari Ushida , Takamitsu Tsukahara , Wakoto Bukawa , Tatsuhiko Kan , Takumi Watanabe , Noritaka Matsubara
摘要： The present invention is to provide a safe antidiarrheal agent and a method for suppressing diarrhea by which an efficient antidiarrheal effect is achieved without using antibiotics or synthetic antibacterial agents that have been conventionally used against infections in livestock and poultry. Antibiotic-resistant pathogenic infections can also be prevented and treated by the present invention. The antidiarrheal agent for livestock and poultry comprising heat-killed bacteria of Enterococcus faecalis EC-12 (FERM ABP-10284) or a treated product thereof as an active ingredient is orally administered to livestock and poultry, particularly to breast-feeding sows and piglets around the weaning period.
摘要翻译： 本发明提供一种安全的止泻剂和抑制腹泻的方法，通过该方法可以在不使用常规用于家畜和家禽感染的抗生素或合成抗菌剂的情况下实现有效的止泻效果。 也可以通过本发明预防和治疗抗生素抗性病原体感染。 包括粪肠球菌EC-12（FERM ABP-10284）的热灭活细菌或其处理产物作为活性成分的家畜和家禽的止泻剂经口给予牲畜和家禽，特别是母乳喂养母猪和周围的母猪 断奶期。
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公开(公告)号：US5192685A
公开(公告)日：1993-03-09
申请号：US512131
申请日：1990-04-20
申请人： Hisako Yasui , Kazuhito Hayakawa , Makoto Ohwaki , Tatsuhiko Kan
发明人： Hisako Yasui , Kazuhito Hayakawa , Makoto Ohwaki , Tatsuhiko Kan
CPC分类号： G01N33/6854 , C12R1/225 , G01N33/5047
摘要： The present invention is to provide an easy, rapid method for screening a great amount of substances having IgA induction potential. The IgA induction potential herein mentioned means the potential to activate and enhance the activity of IgA production cells to produce secretory-type IgA in response to antigen. The present invention is to provide bacterial strains of genus Bifidobacterium obtained by the method for screening substances having IgA induction potential. More specifically, the present invention is to provide Bifidobacterium longum YIT 4062, Bifidobacterium breve YIT 4063 and Bifidobacterium breve YIT 4064. The three strains obtained by the present invention have high IgA induction potential.
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4.发明授权
公开(公告)号：US4859488A
公开(公告)日：1989-08-22
申请号：US96483
申请日：1987-09-15
CPC分类号： A23L2/52 , A23C9/1234 , A23C9/1307 , A23F5/243 , A23L29/30 , A23Y2220/17 , A23Y2300/00
摘要： A liquid food comprising polydextrose and oligosaccharides which are hard to digest and easy to ferment is provided. This liquid food has excellent effect for relieving constipation.
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公开(公告)号：US5118521A
公开(公告)日：1992-06-02
申请号：US354201
申请日：1989-05-19
申请人： Yoshiko Sonoike , Yoichi Kobayashi , Hisaaki Kato , Tatsuhiko Kan
发明人： Yoshiko Sonoike , Yoichi Kobayashi , Hisaaki Kato , Tatsuhiko Kan
摘要： The present invention relates to a method of producing bread containing an oligosaccharide characterized by mixing an oligosaccharide expressed by the formula: Gal-(Gal).sub.n -Glc (wherein Gal denotes a galactose residue, Glc denotes a glucose residue and n denotes one of the integers from 1 to 4) in a raw material used for producing bread.
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公开(公告)号：US4944952A
公开(公告)日：1990-07-31
申请号：US286719
申请日：1988-12-20
CPC分类号： C12P19/04 , A23C9/1206 , A23Y2220/15 , A23Y2240/75
摘要： A method for producing a processed milk containing galactooligosaccharide. An animal milk is treated with a .beta.-galactosidase derived from Streptococcus thermophilus or Lactobacillus bulgaricus so as to change, at least 15% of the lactose contained in the animal milk, into galactooligosaccharide expressed by the following general formula:Gal-(Gal).sub.n Glc
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公开(公告)号：US20110189343A1
公开(公告)日：2011-08-04
申请号：US12525486
申请日：2008-06-26
申请人： Hideo Hasegawa , Tatsuhiko Kan
发明人： Hideo Hasegawa , Tatsuhiko Kan
CPC分类号： C12N1/00 , A23K10/18 , A23L33/135 , A23V2002/00 , A23Y2220/13 , A61K8/99 , A61K35/747 , A61K2800/412 , A61Q19/00 , B82Y5/00 , C12R1/24 , A23V2200/25
摘要： Cells of lactic acid bacteria, which have been obtained by controlling pHs of media in a culturing step and processing steps to a neutral range of, for example, from 5 to 8 or so, have a mode value (particle size) of 1.0 μm or smaller in their particle size distribution. Cells of nano-sized lactic acid bacteria which have such a small particle size are excellent in INF-α producing capacity and are also superb in water dispersibility.
摘要翻译： 通过将培养步骤中的培养基的pH值和加工步骤达到例如5〜8左右的中性范围而获得的乳酸菌细胞的模式值（粒径）为1.0μm， 粒度分布较小。 具有这样小粒径的纳米级乳酸菌细胞在INF-α生产能力上优异，水分散性也优异。
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公开(公告)号：US20070021782A1
公开(公告)日：2007-01-25
申请号：US10557734
申请日：2004-04-20
IPC分类号： A61J17/00
CPC分类号： A61J17/001 , A61J7/0053 , A61J17/006
摘要： A nipple apparatus 10 comprises a nipple 11, and a nipple holding member 15 for holding the nipple 11. A liquid permeating member 25 is provided in the nipple holding member 15, and cap 17 is also provided at the nipple holding member 15. In the cap 17, a drug container 20 covered with a film 21 is housed. Upon engagement of the cap 17 with the nipple holding member 15, a projection 19 at the nipple holding member 15 sticks the film 21.
摘要翻译： 乳头装置10包括乳头11和用于保持乳头11的乳头保持构件15。 在乳头保持构件15中设置有液体渗透构件25，并且帽部17也设置在乳头保持构件15处。 在盖17中容纳有被膜21覆盖的药物容器20。 在帽17与乳头保持构件15接合时，在乳头保持构件15处的突起19粘附在膜21上。
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公开(公告)号：US4957860A
公开(公告)日：1990-09-18
申请号：US112068
申请日：1987-10-26
申请人： Tatsuhiko Kan , Yoichi Kobayashi
发明人： Tatsuhiko Kan , Yoichi Kobayashi
CPC分类号： C12P19/14 , Y10S435/911 , Y10S435/913 , Y10S435/918
摘要： The present invention provides a method of producing oligosaccharides by the reaction between lactose and .beta.-galactosidase from aspergillus oryzae in which an concentration of lactose in an enzyme reaction mixture is between 50 and 90% (w/v) and a reaction temperature is within the range of 55.degree. C. to the temperature at which the .beta.-galactosidase in the reaction mixture is inactivated. This invention therefore makes it possible to obtain the sugar mixture containing high-purity oligosaccharides, small amounts of unreacted lactose and by produced monosaccharides.
摘要翻译： 本发明提供了通过乳糖和来自米曲霉的β-半乳糖苷酶之间的反应制备寡糖的方法，其中酶反应混合物中的乳糖浓度为50-90％（w / v），反应温度在 范围为55℃至反应混合物中β-半乳糖苷酶失活的温度。 因此，本发明使得可以获得含有高纯度寡糖，少量未反应的乳糖和产生的单糖的糖混合物。
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公开(公告)号：US4895801A
公开(公告)日：1990-01-23
申请号：US103416
申请日：1987-10-01
CPC分类号： C12P19/14 , Y10S435/918
摘要： A method for producing oligosaccharides which are represented by the general formula Gal-(Gal)n-Glc (where Gal is a galactose residue, Glc is a glucose residue, and n is an integer from 1 to 4) which is characterized in that lactose or a lactose-containing substance is treated with at least two kinds of .beta.-galactosidases which are produced by different microorganisms. The present invention provides a method of producing oligosaccharides to obtain sweet saccharide mixture which provide sweetness and add oligosaccharides to food and drinks, with a lower increase in calories than that of conventional additives.
摘要翻译： 用于制备由通式Gal-（Gal）n-Glc（其中Gal是半乳糖残基，Glc是葡萄糖残基，n是1至4的整数）表示的寡糖的方法，其特征在于，乳糖 或含有乳糖的物质用至少两种由不同微生物产生的β-半乳糖苷酶处理。 本发明提供一种生产低聚糖以获得甜味糖混合物的方法，其提供甜味并向食品和饮料中添加寡糖，卡路里的热量增加比常规添加剂的增加更低。
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