公开(公告)号：US5420304A

公开(公告)日：1995-05-30

申请号：US128797

申请日：1993-09-29

Applicant: Dan W. Verser ,  Alex Cheung ,  Timothy J. Eggeman ,  William A. Evanko ,  Kevin H. Schilling ,  Manfred Meiser ,  Anthony E. Allen ,  Melville E. D. Hillman ,  George E. Cremeans ,  Edward S. Lipinsky

Inventor： Dan W. Verser ,  Alex Cheung ,  Timothy J. Eggeman ,  William A. Evanko ,  Kevin H. Schilling ,  Manfred Meiser ,  Anthony E. Allen ,  Melville E. D. Hillman ,  George E. Cremeans ,  Edward S. Lipinsky

IPC: C07C51/48 ,  C07D319/12 ,  C08J5/18 ,  C08L67/04 ,  C09D167/04 ,  C07D319/00

CPC classification number: C07D319/12 ,  C07C51/48 ,  C08J5/18 ,  C08L67/04 ,  C09D167/04 ,  B01J2219/1942 ,  C08J2367/04 ,  Y02P20/125

Abstract: Disclosed is a novel integrated process for production of cyclic esters which includes recovery of starting materials, such as lactic acid from a dilute aqueous lactic acid-containing solution, by solvent extraction. The starting materials are then formed into cyclic esters by removal of water wherein the concentration of higher molecular weight oligomers is maintained below about 20 wt % of the reaction composition. The process further includes providing a recovery solvent for the reaction composition and separating the cyclic esters from the starting materials and higher molecular weight oligomers by liquid-liquid equilibrium separation. The present invention is further directed toward independent novel unit operations of the overall process. The present invention provides for the efficient production and recovery of cyclic esters due to integration of the various unit operations by use of appropriate solvents and recycle streams. In addition, high rates of conversion of starting materials and high rates of selective production of cyclic esters are achieved by appropriate control of process parameters.

Abstract translation: 公开了一种用于生产环酯的新型整合方法，其包括通过溶剂萃取从稀酸含水乳液中回收原料如乳酸。 然后将原料通过除去水形成环状酯，其中高分子量低聚物的浓度保持在反应组合物的约20重量％以下。 该方法还包括提供反应组合物的回收溶剂，并通过液 - 液平衡分离从起始原料和较高分子量的低聚物中分离环酯。 本发明进一步针对整个过程的独立的新颖的单元操作。 本发明提供了通过使用合适的溶剂和循环流将各种单元操作整合在一起的环酯的有效生产和回收。 此外，起始材料的高转化率和选择性生产环酯的高速率通过适当控制工艺参数来实现。

公开(公告)号：US07244498B2

公开(公告)日：2007-07-17

申请号：US11120650

申请日：2005-05-03

Applicant: Ronald Lee Cook ,  Silvia DeVito Luebben ,  Andrew William Myers ,  Bryan Matthew Smith ,  Brian John Elliott ,  Cory Kreutzer ,  Carolina Wilson ,  Manfred Meiser

Inventor： Ronald Lee Cook ,  Silvia DeVito Luebben ,  Andrew William Myers ,  Bryan Matthew Smith ,  Brian John Elliott ,  Cory Kreutzer ,  Carolina Wilson ,  Manfred Meiser

IPC: B32B5/66

CPC classification number: B01J2/30 ,  B82Y30/00 ,  C01P2002/72 ,  C01P2004/04 ,  C01P2004/64 ,  C01P2006/12 ,  C08K3/22 ,  C08K3/346 ,  C08K9/04 ,  C09C1/24 ,  C09C1/407 ,  C09D5/082 ,  C09D163/00 ,  Y10T428/2982 ,  Y10T428/2991 ,  Y10T428/2993 ,  Y10T428/2995 ,  Y10T428/2998 ,  C08L2666/54

Abstract: Surface-modified nanoparticles of boehmite, and methods for preparing the same. Aluminum oxyhydroxide nanoparticles are surface modified by reaction with selected amounts of organic acids. In particular, the nanoparticle surface is modified by reactions with two or more different carboxylic acids, at least one of which is an organic carboxylic acid. The product is a surface modified boehmite nanoparticle that has an inorganic aluminum oxyhydroxide core, or part aluminum oxyhydroxide core and a surface-bonded organic shell. Organic carboxylic acids of this invention contain at least one carboxylic acid group and one carbon-hydrogen bond. One embodiment of this invention provides boehmite nanoparticles that have been surface modified with two or more acids one of which additional carries at least one reactive functional group. Another embodiment of this invention provides boehmite nanoparticles that have been surface modified with multiple acids one of which has molecular weight or average molecular weight greater than or equal to 500 Daltons. Yet, another embodiment of this invention provides boehmite nanoparticles that are surface modified with two or more acids one of which is hydrophobic in nature and has solubility in water of less than 15 by weight. The products of the methods of this invention have specific useful properties when used in mixture with liquids, as filler in solids, or as stand-alone entities.

Abstract translation: 勃姆石的表面改性纳米颗粒及其制备方法。 羟基氧化铝纳米颗粒通过与选定量的有机酸反应进行表面改性。 特别地，通过与两种或多种不同羧酸的反应来修饰纳米颗粒表面，其中至少一种是有机羧酸。 该产品是具有无机氢氧化铝核心或部分羟基氧化铝核心和表面键合有机壳体的表面改性勃姆石纳米颗粒。 本发明的有机羧酸含有至少一个羧酸基和一个碳 - 氢键。 本发明的一个实施方案提供已经用两种或多种酸进行表面改性的勃姆石纳米颗粒，其中一种还含有至少一个反应性官能团。 本发明的另一个实施方案提供已经用多种酸进行表面改性的勃姆石纳米颗粒，其中一种具有大于或等于500道尔顿的分子量或平均分子量。 然而，本发明的另一个实施方案提供了用两种或更多种酸进行表面改性的勃姆石纳米粒子，其中一种酸性质是疏水性的，并且在水中的溶解度小于15重量％。 当与液体混合使用时，本发明方法的产品具有特定的有用特性，作为固体中的填料或作为独立实体。

公开(公告)号：US20070098990A1

公开(公告)日：2007-05-03

申请号：US11120650

申请日：2005-05-03

Applicant: Ronald Cook ,  Silvia Luebben ,  Andrew Myers ,  Bryan Smith ,  Brian Elliott ,  Cory Kreutzer ,  Carolina Wilson ,  Manfred Meiser

Inventor： Ronald Cook ,  Silvia Luebben ,  Andrew Myers ,  Bryan Smith ,  Brian Elliott ,  Cory Kreutzer ,  Carolina Wilson ,  Manfred Meiser

IPC: B32B1/00 ,  C08K9/02

CPC classification number: B01J2/30 ,  B82Y30/00 ,  C01P2002/72 ,  C01P2004/04 ,  C01P2004/64 ,  C01P2006/12 ,  C08K3/22 ,  C08K3/346 ,  C08K9/04 ,  C09C1/24 ,  C09C1/407 ,  C09D5/082 ,  C09D163/00 ,  Y10T428/2982 ,  Y10T428/2991 ,  Y10T428/2993 ,  Y10T428/2995 ,  Y10T428/2998 ,  C08L2666/54

Abstract: Surface-modified nanoparticles of boehmite, and methods for preparing the same. Aluminum oxyhydroxide nanoparticles are surface modified by reaction with selected amounts of organic acids. In particular, the nanoparticle surface is modified by reactions with two or more different carboxylic acids, at least one of which is an organic carboxylic acid. The product is a surface modified boehmite nanoparticle that has an inorganic aluminum oxyhydroxide core, or part aluminum oxyhydroxide core and a surface-bonded organic shell. Organic carboxylic acids of this invention contain at least one carboxylic acid group and one carbon-hydrogen bond. One embodiment of this invention provides boehmite nanoparticles that have been surface modified with two or more acids one of which additional carries at least one reactive functional group. Another embodiment of this invention provides boehmite nanoparticles that have been surface modified with multiple acids one of which has molecular weight or average molecular weight greater than or equal to 500 Daltons. Yet, another embodiment of this invention provides boehmite nanoparticles that are surface modified with two or more acids one of which is hydrophobic in nature and has solubility in water of less than 15 by weight. The products of the methods of this invention have specific useful properties when used in mixture with liquids, as filler in solids, or as stand-alone entities.

Abstract translation: 勃姆石的表面改性纳米颗粒及其制备方法。 羟基氧化铝纳米颗粒通过与选定量的有机酸反应进行表面改性。 特别地，通过与两种或多种不同羧酸的反应来修饰纳米颗粒表面，其中至少一种是有机羧酸。 该产品是具有无机氢氧化铝核心或部分羟基氧化铝核心和表面键合有机壳体的表面改性勃姆石纳米颗粒。 本发明的有机羧酸含有至少一个羧酸基和一个碳 - 氢键。 本发明的一个实施方案提供已经用两种或多种酸进行表面改性的勃姆石纳米颗粒，其中一种还含有至少一个反应性官能团。 本发明的另一个实施方案提供已经用多种酸进行表面改性的勃姆石纳米颗粒，其中一种具有大于或等于500道尔顿的分子量或平均分子量。 然而，本发明的另一个实施方案提供了用两种或更多种酸进行表面改性的勃姆石纳米粒子，其中一种酸性质是疏水性的，并且在水中的溶解度小于15重量％。 当与液体混合使用时，本发明方法的产品具有特定的有用特性，作为固体中的填料或作为独立实体。

公开(公告)号：US5750732A

公开(公告)日：1998-05-12

申请号：US444954

申请日：1995-05-19

Applicant: Dan W. Verser ,  Alex Cheung ,  Timothy J. Eggeman ,  William A. Evanko ,  Kevin H. Schilling ,  Manfred Meiser ,  Anthony E. Allen ,  Melville E. D. Hillman ,  George E. Cremeans ,  Edward S. Lipinsky

Inventor： Dan W. Verser ,  Alex Cheung ,  Timothy J. Eggeman ,  William A. Evanko ,  Kevin H. Schilling ,  Manfred Meiser ,  Anthony E. Allen ,  Melville E. D. Hillman ,  George E. Cremeans ,  Edward S. Lipinsky

IPC: C07C51/48 ,  C07D319/12 ,  C08J5/18 ,  C08L67/04 ,  C09D167/04 ,  C07D321/00 ,  C07D321/10

CPC classification number: C07D319/12 ,  C07C51/48 ,  C08J5/18 ,  C08L67/04 ,  C09D167/04 ,  B01J2219/1942 ,  C08J2367/04 ,  Y02P20/125

Abstract: Disclosed is a novel integrated process for production of cyclic esters which includes recovery of starting materials, such as lactic acid from a dilute aqueous lactic acid-containing solution, by solvent extraction. The starting materials are then formed into cyclic esters by removal of water wherein the concentration of higher molecular weight oligomers is maintained below about 20 wt % of the reaction composition. The process further includes providing a recovery solvent for the reaction composition and separating the cyclic esters from the starting materials and higher molecular weight oligomers by liquid-liquid equilibrium separation. The present invention is further directed toward independent novel unit operations of the overall process. The present invention provides for the efficient production and recovery of cyclic esters due to integration of the various unit operations by use of appropriate solvents and recycle streams. In addition, high rates of conversion of starting materials and high rates of selective production of cyclic esters are achieved by appropriate control of process parameters.