公开(公告)号：US20080101987A1

公开(公告)日：2008-05-01

申请号：US11591367

申请日：2006-10-31

申请人： Selwayan Saini ,  Marco Fabio Cardosi ,  Leanne Mills ,  Stephen Patrick Blythe

发明人： Selwayan Saini ,  Marco Fabio Cardosi ,  Leanne Mills ,  Stephen Patrick Blythe

IPC分类号： G01N21/00

CPC分类号： G01N21/69 ,  G01N21/76 ,  G01N2021/6439

摘要： An analytical test strip for the determination of an analyte (such as glucose) in a bodily fluid sample (for example, a whole blood sample) includes a substrate layer, an electroluminescent lamp disposed on the substrate layer, a sample chamber configured for receiving the bodily fluid sample disposed above the substrate layer; and an enzymatic reagent disposed within the sample chamber. Moreover, the electroluminescent lamp is configured to emit light, the light being visible to a user of the analytical test strip and providing the user with spatial awareness of the analytical test strip.

摘要翻译： 用于测定体液样品（例如，全血样品）中的分析物（例如葡萄糖）的分析测试条包括基底层，设置在基底层上的电致发光灯，被配置为接收 设置在基底层上方的体液样品; 和设置在样品室内的酶试剂。 此外，电致发光灯被配置为发光，所述光对于分析测试条的用户可见并且向用户提供分析测试条的空间意识。

公开(公告)号：US07351770B2

公开(公告)日：2008-04-01

申请号：US10957441

申请日：2004-09-30

申请人： Zuifang Liu ,  James Iain Rodgers ,  Geoffrey Lillie ,  Marco Fabio Cardosi

发明人： Zuifang Liu ,  James Iain Rodgers ,  Geoffrey Lillie ,  Marco Fabio Cardosi

IPC分类号： C08F271/02

CPC分类号： C12Q1/004

摘要： Ionic hydrophilic high molecular weight redox polymers for use in enzymatic electrochemical-based sensors include a hydrophilic polymer (such as a hydrophilic polymer backbone) with ionic portions (e.g., cationic monomers incorporated in the hydrophilic polymer backbone) and a plurality of attached redox mediators. The redox mediators can be, for example, covalently attached to the hydrophilic polymer in a pendant manner. An exemplary cationic hydrophilic high molecular weight redox polymer is synthesized by co-polymerization of a hydrophilic acrylamide monomer, [2-(acryloyloxy)ethyl]trimethyl ammonium chloride and vinyl ferrocene.

摘要翻译： 用于酶电化学传感器的离子型亲水性高分子量氧化还原聚合物包括具有离子部分的亲水性聚合物（例如亲水性聚合物主链）（例如并入亲水性聚合物主链中的阳离子单体）和多个附着的氧化还原介体。 氧化还原介体可以例如以悬挂的方式与亲水性聚合物共价连接。 通过亲水丙烯酰胺单体[2-（丙烯酰氧基）乙基]三甲基氯化铵和乙烯基二茂铁的共聚合来合成示例性的阳离子亲水性高分子量氧化还原聚合物。

公开(公告)号：US20080101986A1

公开(公告)日：2008-05-01

申请号：US11591313

申请日：2006-10-31

申请人： Selwayan Saini ,  Marco Fabio Cardosi ,  Leanne Mills ,  Stephen Patrick Blythe

发明人： Selwayan Saini ,  Marco Fabio Cardosi ,  Leanne Mills ,  Stephen Patrick Blythe

IPC分类号： G01N21/00

CPC分类号： G01N21/76 ,  G01N21/69 ,  G01N2021/6439

摘要： An analytical test strip for the determination of an analyte (such as glucose) in a bodily fluid sample (for example, a whole blood sample) includes a substrate layer, an electroluminescent module disposed on the substrate layer, a sample chamber configured for receiving the bodily fluid sample disposed above the substrate layer; and a fluorophore-containing photometric enzymatic reagent disposed within the sample chamber. Moreover, the electroluminescent module is in optical communication with the sample chamber and is configured to emit light that facilitates a fluorescent chemical reaction sequence involving the fluorophore-containing photometric enzymatic reagent and the analyte.

摘要翻译： 用于测定体液样品（例如全血样品）中的分析物（例如葡萄糖）的分析测试条包括基底层，设置在基底层上的电致发光模块，被配置为接收 设置在基底层上方的体液样品; 和设置在样品室内的含荧光团的光度测定酶试剂。 此外，电致发光模块与样品室光学连通，并且被配置为发射促进涉及含荧光团的光度测定酶试剂和分析物的荧光化学反应序列的光。

公开(公告)号：US20080101984A1

公开(公告)日：2008-05-01

申请号：US11591316

申请日：2006-10-31

申请人： Selwayan Saini ,  Marco Fabio Cardosi ,  Leanne Mills ,  Stephen Patrick Blythe

发明人： Selwayan Saini ,  Marco Fabio Cardosi ,  Leanne Mills ,  Stephen Patrick Blythe

IPC分类号： G01N21/76

CPC分类号： G01N21/69 ,  G01N21/76 ,  G01N2021/6439

摘要： A method for the determination of an analyte in a bodily fluid sample includes transferring a bodily fluid sample (such as a whole blood sample) to a sample chamber of an analytical test strip. The analytical test strip to which the bodily fluid sample is transferred has a substrate layer, an electroluminescent module disposed on the substrate layer and in optical communication with the sample chamber, and a fluorophore-containing photometric enzymatic reagent disposed within the sample chamber. In addition, the electroluminescent module is configured to emit light that facilitates a fluorescent chemical reaction sequence involving the fluorophore-containing photometric enzymatic reagent and the analyte. The method also includes exposing the fluorophore-containing photometric enzymatic reagent to the bodily fluid sample and to light emitted from the electroluminescent module such that photons are emitted from the fluorophore-containing photometric enzymatic reagent via a fluorescent chemical reaction sequence. Moreover, the method includes detecting the photons with a photodetector.

摘要翻译： 用于测定体液样品中的分析物的方法包括将体液样品（例如全血样品）转移到分析测试条的样品室。 体液样本被转移到的分析测试条具有衬底层，设置在衬底层上并与样品室光学连通的电致发光模块，以及置于样品室内的含荧光团的光度测定试剂。 此外，电致发光模块被配置为发射促进包含含荧光团的光度测定酶试剂和分析物的荧光化学反应序列的光。 该方法还包括将含荧光团的光度测试酶试剂暴露于体液样品和从电致发光模块发射的光，使得通过荧光化学反应顺序从含荧光团的光度测定酶试剂发射光子。 此外，该方法包括用光电检测器检测光子。

公开(公告)号：US07740801B2

公开(公告)日：2010-06-22

申请号：US11591138

申请日：2006-10-31

申请人： Selwayan Saini ,  Marco Fabio Cardosi ,  Leanne Mills ,  Stephen Patrick Blythe

发明人： Selwayan Saini ,  Marco Fabio Cardosi ,  Leanne Mills ,  Stephen Patrick Blythe

IPC分类号： G01N21/76

CPC分类号： G01N21/69 ,  G01N21/76 ,  G01N2021/6439

摘要： A system for the determination of an analyte in a bodily fluid sample includes an analytical test strip and an analytical meter. The analytical test strip has a substrate layer, an electroluminescent component (either an electroluminescent module and/or an electroluminescent lamp) disposed on the substrate layer, and a sample chamber configured for receiving a bodily fluid sample disposed above the substrate layer. Moreover, the analytical meter is configured for insertion of the analytical test strip therein and subsequent determination of the analyte.

摘要翻译： 用于测定体液样品中的分析物的系统包括分析测试条和分析计。 分析测试条具有设置在基底层上的基底层，电致发光元件（电致发光模块和/或电致发光灯），以及被配置为接收设置在基底层上方的体液样品的样本室。 此外，分析仪被配置用于在其中插入分析测试条并随后确定分析物。

公开(公告)号：US20080100689A1

公开(公告)日：2008-05-01

申请号：US11591366

申请日：2006-10-31

申请人： Selwayan Saini ,  Marco Fabio Cardosi ,  Leanne Mills ,  Stephen Patrick Blythe

发明人： Selwayan Saini ,  Marco Fabio Cardosi ,  Leanne Mills ,  Stephen Patrick Blythe

IPC分类号： B41J2/435

CPC分类号： C12Q1/001 ,  G01N21/66 ,  G01N21/8483

摘要： A method for manufacturing an analytical test strip with an electroluminescent component (either an electroluminescent module and/or an electroluminescent lamp) includes sequentially applying to a substrate layer, a rear electrode layer disposed on the substrate layer, an electrically-insulating layer disposed over the rear electrode layer, a phosphor layer disposed over the electrically insulating layer, and a front electrode layer (at least a portion of which is translucent) disposed over the phosphor layer. The sequential application is accomplished such that it forms an electroluminescent component of the analytical test strip.

摘要翻译： 制造具有电致发光元件（电致发光模块和/或电致发光灯）的分析测试条的方法包括：顺序地施加到基底层，设置在基底层上的背面电极层，设置在基底层上的电绝缘层 背面电极层，设置在电绝缘层上的荧光体层和设置在荧光体层上的前电极层（其至少一部分是半透明的）。 顺序应用完成，使得其形成分析测试条的电致发光部件。

公开(公告)号：US20080101985A1

公开(公告)日：2008-05-01

申请号：US11591138

申请日：2006-10-31

申请人： Selwayan Saini ,  Marco Fabio Cardosi ,  Leanne Mills ,  Stephen Patrick Blythe

发明人： Selwayan Saini ,  Marco Fabio Cardosi ,  Leanne Mills ,  Stephen Patrick Blythe

IPC分类号： G01N21/00

CPC分类号： G01N21/69 ,  G01N21/76 ,  G01N2021/6439

摘要： A system for the determination of an analyte in a bodily fluid sample includes an analytical test strip and an analytical meter. The analytical test strip has a substrate layer, an electroluminescent component (either an electroluminescent module and/or an electroluminescent lamp) disposed on the substrate layer, and a sample chamber configured for receiving a bodily fluid sample disposed above the substrate layer. Moreover, the analytical meter is configured for insertion of the analytical test strip therein and subsequent determination of the analyte.

摘要翻译： 用于测定体液样品中的分析物的系统包括分析测试条和分析计。 分析测试条具有设置在基底层上的基底层，电致发光元件（电致发光模块和/或电致发光灯），以及被配置为接收设置在基底层上方的体液样品的样本室。 此外，分析仪被配置用于在其中插入分析测试条并随后确定分析物。