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公开(公告)号：US20130310781A1
公开(公告)日：2013-11-21
申请号：US13989569
申请日：2011-11-25
CPC分类号： A61L26/0095 , A61F13/0216 , A61L15/26 , A61L15/425 , A61L15/585 , A61L24/0073 , A61M1/0088 , C08G77/12 , C08G77/20 , C08L83/04 , C08L83/00
摘要： A curable composition apportioned between at least one Part A and at least one Part B, the Parts sealed within barrier means preventing contamination, the at least one Part A comprising: (i) one or more alkenyl-group containing prepolymers having at least one alkenyl group or moiety per molecule, and the at least one Part B comprising: (ii) one or more SiH-containing prepolymers having at least one Si—H unit per molecule; the composition additionally comprising: (iii) a catalyst for curing by addition of alkenyl-containing prepolymer (i) to SiH-containing prepolymer (ii), wherein prepolymer (ii) is substantially absent from Part A and prepolymer (i) is substantially absent from Part B, methods for preparing the composition, methods for sterilisation thereof, medical and non-medical use thereof, a device incorporating the composition, and a precursor therefor including its sterilisable precursor composition, in particular a terminally sterilisable or terminally sterile composition for medical use, particularly in wound therapy, more particularly as a wound packing material which can be shaped and configured to the shape of a wound, most particularly for application in negative pressure wound therapy (NPWT).
摘要翻译： 在至少一个部分A和至少一个部分B之间分配的可固化组合物，密封在屏障内的部分意味着防止污染，所述至少一个部分A包含：（i）一种或多种含链烯基的预聚物，其具有至少一个烯基 每个分子的基团或部分，和至少一个部分B，其包含：（ii）每分子具有至少一个Si-H单元的一种或多种含SiH的预聚物; 所述组合物另外包含：（iii）通过向含SiH的预聚物（ii）中加入含烯基的预聚物（i）固化的催化剂，其中预聚物（ii）基本上不在部分A中，预聚物（i）基本上不存在 来自B部分的方法，用于制备组合物的方法，其灭菌方法，医疗和非医疗用途，包含该组合物的装置及其前体，包括其可灭菌的前体组合物，特别是用于医疗的可灭菌的或终末无菌的组合物 特别是在伤口治疗中，特别是作为伤口包装材料，其可被成形和构造成伤口形状，特别适用于负压伤口治疗（NPWT）。
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公开(公告)号：US10369250B2
公开(公告)日：2019-08-06
申请号：US13989569
申请日：2011-11-25
IPC分类号： A61M1/00 , A61L26/00 , A61L15/26 , A61L15/42 , A61L15/58 , C08L83/04 , A61F13/02 , A61L24/00 , C08G77/12 , C08G77/20
摘要： A curable composition apportioned between at least one Part A and at least one Part B, the Parts sealed within barrier means preventing contamination, the at least one Part A comprising: (i) one or more alkenyl-group containing prepolymers having at least one alkenyl group or moiety per molecule, and the at least one Part B comprising: (ii) one or more SiH-containing prepolymers having at least one Si—H unit per molecule; the composition additionally comprising: (iii) a catalyst for curing by addition of alkenyl-containing prepolymer (i) to SiH-containing prepolymer (ii), wherein prepolymer (ii) is substantially absent from Part A and prepolymer (i) is substantially absent from Part B, methods for preparing the composition, methods for sterilisation thereof, medical and non-medical use thereof, a device incorporating the composition, and a precursor therefor including its sterilisable precursor composition, in particular a terminally sterilisable or terminally sterile composition for medical use, particularly in wound therapy, more particularly as a wound packing material which can be shaped and configured to the shape of a wound, most particularly for application in negative pressure wound therapy (NPWT).
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公开(公告)号：US10537657B2
公开(公告)日：2020-01-21
申请号：US13989569
申请日：2011-11-25
IPC分类号： A61M1/00 , A61L26/00 , A61L15/26 , A61L15/42 , A61L15/58 , C08L83/04 , A61F13/02 , A61L24/00 , C08G77/12 , C08G77/20
摘要： A curable composition apportioned between at least one Part A and at least one Part B, the Parts sealed within barrier means preventing contamination, the at least one Part A comprising: (i) one or more alkenyl-group containing prepolymers having at least one alkenyl group or moiety per molecule, and the at least one Part B comprising: (ii) one or more SiH-containing prepolymers having at least one Si—H unit per molecule; the composition additionally comprising: (iii) a catalyst for curing by addition of alkenyl-containing prepolymer (i) to SiH-containing prepolymer (ii), wherein prepolymer (ii) is substantially absent from Part A and prepolymer (i) is substantially absent from Part B, methods for preparing the composition, methods for sterilisation thereof, medical and non-medical use thereof, a device incorporating the composition, and a precursor therefor including its sterilisable precursor composition, in particular a terminally sterilisable or terminally sterile composition for medical use, particularly in wound therapy, more particularly as a wound packing material which can be shaped and configured to the shape of a wound, most particularly for application in negative pressure wound therapy (NPWT).
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公开(公告)号：US20130310780A1
公开(公告)日：2013-11-21
申请号：US13989560
申请日：2011-11-25
CPC分类号： A61L15/425 , A61L15/26 , A61L15/58 , A61L24/0073 , A61L26/0095 , A61M1/00 , C08L83/04
摘要： A curable composition apportioned between at least one Part A and at least one Part B, the Parts sealed within barrier means in manner to prevent contamination thereof, the composition comprising: (i) one or more alkenyl-containing prepolymers having at least one alkenyl moiety per molecule, ii) one or more SiH-containing prepolymers having at least one SiH unit per molecule, and additionally: (iii) a catalyst for curing by addition of alkenyl-containing prepolymer (i) to SiH-containing prepolymer (ii), wherein the at least one Part A and at least one Part B are provided within or upon at least two respective receptacles or supports and are adapted to be dispensed or released therefrom in cooperative manner facilitating intimate contact and curing thereof, wherein the receptacle(s) or support(s) for at least one of Part A and Part B is thermally stable at elevated temperature of 123 C for a period in excess of 18 hours, methods for preparing the composition, methods for sterilisation thereof, medical and non-medical use thereof, a device incorporating the composition, and a precursor therefor including its sterilisable precursor composition, in particular a terminally sterilisable or terminally sterile composition for medical use, particularly in wound therapy, more particularly as a wound packing material which can be shaped and configured to the shape of a wound, most particularly for application in negative pressure wound therapy (NPWT).
摘要翻译： 分配在至少一个部分A和至少一个部分B之间的可固化组合物，密封在阻挡装置内的部分以防止其污染的方式，所述组合物包含：（i）一种或多种含烯基的预聚物，其具有至少一个烯基部分 每个分子，ii）一种或多种每分子具有至少一个SiH单元的含SiH的预聚物，另外：（iii）通过向含SiH的预聚物（ii）中加入含链烯基的预聚物（i）固化的催化剂， 其中所述至少一个部分A和至少一个部分B设置在所述至少两个相应的容器或支撑体内或之上，并且适于以协作的方式分配或释放，以促进其紧密接触和固化，其中， 或者对于部分A和部分B中的至少一个的载体在123℃的升高的温度下热稳定超过18小时的时间，制备组合物的方法，灭菌方法t 特别是在医疗用途的终端可灭菌或终末无菌组合物中，特别是在伤口治疗中，更具体地说，作为伤口包装 可以被成形和构造成伤口形状的材料，最特别适用于负压伤口治疗（NPWT）。
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