-
Patent Agency Ranking
公开(公告)号：US6004580A
公开(公告)日：1999-12-21
申请号：US727545
申请日：1997-11-12
Applicant: Sune Backlund , Folke Eriksson , Maria Rantala , Pertti Rantala , Kari Varho
Inventor： Sune Backlund , Folke Eriksson , Maria Rantala , Pertti Rantala , Kari Varho
CPC classification number: A61K9/06 , A61K9/1075 , Y10S514/937 , Y10S514/938 , Y10S514/944
Abstract: A pharmaceutical composition containing a microemulsion made up of a hydrophilic component, a lipophilic component, a surfactant and a drug, where the hydrophilic component, the lipophilic component and the surfactant form, when examined on a macroscopic scale, a one-phase solution. The hydrophilic component is dispersed as colloidal droplets in the lipophilic component, or the lipophilic component is dispersed as colloidal droplets in the hydrophilic component. According to still another alternative, the hydrophilic and the lipophilic components form a microemulsion with bicontinuous structure where the components form elongated adjacent channels. The drug is dissolved in the dispersed component or, in the case of a microemulsion with bicontinuous structure, in the hydrophilic or the lipophilic component. The microemulsion is stabilized by means of the surfactant. It is characteristic that a gelatinizer and water are added to the microemulsion thereby bringing the microemulsion into a gel form.
Abstract translation: PCT No.PCT / FI95 / 00234 Sec。 371日期：1997年11月12日 102（e）日期1997年11月12日PCT提交1995年4月28日PCT公布。 WO95 / 31969 PCT公开 日期：1995年11月30日含有由亲水性成分，亲油性成分，表面活性剂和药物构成的微乳液的药物组合物，其中亲水性成分，亲油性成分和表面活性剂形成时，以宏观尺度进行检查时， 相解决方案。 亲水性成分作为胶体液滴分散在亲油性成分中，或者亲油性成分作为胶体液滴分散在亲水性成分中。 根据另一替代方案，亲水性和亲油性组分形成具有双连续结构的微乳液，其中组分形成细长的相邻通道。 将该药物溶解在分散的组分中，或者在具有双连续结构的微乳液的情况下，在亲水或亲油组分中。 微乳液通过表面活性剂稳定。 特征在于，将微凝胶和水加入到微乳液中，从而使微乳液成为凝胶形式。
-
公开(公告)号：US08309591B2
公开(公告)日：2012-11-13
申请号：US12953691
申请日：2010-11-24
Applicant: Mirja Huhtinen , Piritta Koistinen , Lasse Leino , Maria Rantala , Helena Kaukinen , Kaija Af Ursin
Inventor： Mirja Huhtinen , Piritta Koistinen , Lasse Leino , Maria Rantala , Helena Kaukinen , Kaija Af Ursin
CPC classification number: A61K9/0056 , A61K9/006 , A61K9/06 , A61K9/107 , A61K31/415
Abstract: The present invention relates to a veterinary composition in a semisolid form adapted for transmucosal administration for providing sedation and analgesia in large animals such as horses and cattle. The semisolid transmucosal composition of the invention comprises detomidine or a pharmaceutically acceptable salt thereof as an active ingredient. The composition provides a rapid onset of action while having low irritation potential in the oral mucosa.
Abstract translation: 本发明涉及适于经粘膜给药的半固体形式的兽用组合物，用于在大型动物如马和牛中提供镇静和止痛。 本发明的半固体经粘膜组合物包括脱甲基或其药学上可接受的盐作为活性成分。 组合物在口腔粘膜中具有低刺激潜力的同时提供快速起效作用。
-
公开(公告)号：US07863311B2
公开(公告)日：2011-01-04
申请号：US11667100
申请日：2005-11-03
Applicant: Mirja Huhtinen , Piritta Koistinen , Lasse Leino , Maria Rantala , Helena Kaukinen , Kaija Af Ursin
Inventor： Mirja Huhtinen , Piritta Koistinen , Lasse Leino , Maria Rantala , Helena Kaukinen , Kaija Af Ursin
IPC: A01N43/50
CPC classification number: A61K9/0056 , A61K9/006 , A61K9/06 , A61K9/107 , A61K31/415
Abstract: The present invention relates to a veterinary composition in a semisolid form adapted for transmucosal administration for providing sedation and analgesia in large animals such as horses and cattle. The semisolid transmucosal composition of the invention comprises detomidine or a pharmaceutically acceptable salt thereof as an active ingredient. The composition provides a rapid onset of action while having low irritation potential in the oral mucosa.
Abstract translation: 本发明涉及适于经粘膜给药的半固体形式的兽用组合物，用于在大型动物如马和牛中提供镇静和止痛。 本发明的半固体经粘膜组合物包括脱甲基或其药学上可接受的盐作为活性成分。 组合物在口腔粘膜中具有低刺激潜力的同时提供快速起效作用。
-
公开(公告)号：US20110071203A1
公开(公告)日：2011-03-24
申请号：US12953691
申请日：2010-11-24
Applicant: Mirja Huhtinen , Piritta Koistinen , Lasse Leino , Maria Rantala , Helena Kaukinen , Kaija AF Ursin
Inventor： Mirja Huhtinen , Piritta Koistinen , Lasse Leino , Maria Rantala , Helena Kaukinen , Kaija AF Ursin
IPC: A61K31/4174 , A61P23/00 , A61P29/00
CPC classification number: A61K9/0056 , A61K9/006 , A61K9/06 , A61K9/107 , A61K31/415
Abstract: The present invention relates to a veterinary composition in a semisolid form adapted for transmucosal administration for providing sedation and analgesia in large animals such as horses and cattle. The semisolid transmucosal composition of the invention comprises detomidine or a pharmaceutically acceptable salt thereof as an active ingredient. The composition provides a rapid onset of action while having low irritation potential in the oral mucosa.
Abstract translation: 本发明涉及适于经粘膜给药的半固体形式的兽用组合物，用于在大型动物如马和牛中提供镇静和止痛。 本发明的半固体经粘膜组合物包括脱甲基或其药学上可接受的盐作为活性成分。 组合物在口腔粘膜中具有低刺激潜力的同时提供快速起效作用。
-
公开(公告)号：US20070299121A1
公开(公告)日：2007-12-27
申请号：US11667100
申请日：2005-11-03
Applicant: Mirja Huhtinen , Piritta Koistinen , Lasse Leino , Maria Rantala , Helena Kaukinen , Kaija Af Ursin
Inventor： Mirja Huhtinen , Piritta Koistinen , Lasse Leino , Maria Rantala , Helena Kaukinen , Kaija Af Ursin
IPC: A61K31/415 , A61P43/00
CPC classification number: A61K9/0056 , A61K9/006 , A61K9/06 , A61K9/107 , A61K31/415
Abstract: The present invention relates to a veterinary composition in a semisolid form adapted for transmucosal administration for providing sedation and analgesia in large animals such as horses and cattle. The semisolid transmucosal composition of the invention comprises detomidine or a pharmaceutically acceptable salt thereof as an active ingredient. The composition provides a rapid onset of action while having low irritation potential in the oral mucosa.
Abstract translation: 本发明涉及适于经粘膜给药的半固体形式的兽用组合物，用于在大型动物如马和牛中提供镇静和止痛。 本发明的半固体经粘膜组合物包括脱甲基或其药学上可接受的盐作为活性成分。 组合物在口腔粘膜中具有低刺激潜力的同时提供快速起效作用。
-
-
-
-
Search Results
5
records
(took 0.011 seconds)
