Targets for controlling cellular growth and for diagnostic methods
    6.
    发明申请
    Targets for controlling cellular growth and for diagnostic methods 审中-公开
    控制细胞生长和诊断方法的目标

    公开(公告)号:US20050003390A1

    公开(公告)日:2005-01-06

    申请号:US10789378

    申请日:2004-02-26

    IPC分类号: C12Q1/68 G01N33/574

    摘要: A method of identifying a compound that induces apoptosis is disclosed. The method includes identifying compounds that inhibit the expression and/or activity of a target. Also disclosed are methods for inducing apoptosis by inhibiting one of the targets. The invention further includes methods for the diagnosis of a tumor that include determining the level of at least one of the targets as a biomarker in a patient sample, the level of the biomarker being indicative of the presence of tumor cells.

    摘要翻译: 公开了鉴定诱导细胞凋亡的化合物的方法。 该方法包括鉴定抑制靶标表达和/或活性的化合物。 还公开了通过抑制目标之一诱导细胞凋亡的方法。 本发明还包括用于诊断肿瘤的方法,所述方法包括确定至少一种靶标的水平作为患者样品中的生物标志物,所述生物标志物的水平指示肿瘤细胞的存在。