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    Targets for controlling cellular growth and for diagnostic methods
    1.
    发明申请
    Targets for controlling cellular growth and for diagnostic methods 审中-公开
    控制细胞生长和诊断方法的目标

    公开(公告)号：US20050003390A1

    公开(公告)日：2005-01-06

    申请号：US10789378

    申请日：2004-02-26

    申请人： Sergey Axenovich ,  Robert Stull ,  Marina Gelman ,  Kitty Chui ,  Dean Ng

    发明人： Sergey Axenovich ,  Robert Stull ,  Marina Gelman ,  Kitty Chui ,  Dean Ng

    IPC分类号： C12Q1/68 ,  G01N33/574

    CPC分类号： G01N33/57419 ,  C12Q1/6886 ,  C12Q2600/158 ,  G01N2510/00

    摘要： A method of identifying a compound that induces apoptosis is disclosed. The method includes identifying compounds that inhibit the expression and/or activity of a target. Also disclosed are methods for inducing apoptosis by inhibiting one of the targets. The invention further includes methods for the diagnosis of a tumor that include determining the level of at least one of the targets as a biomarker in a patient sample, the level of the biomarker being indicative of the presence of tumor cells.

    摘要翻译： 公开了鉴定诱导细胞凋亡的化合物的方法。 该方法包括鉴定抑制靶标表达和/或活性的化合物。 还公开了通过抑制目标之一诱导细胞凋亡的方法。 本发明还包括用于诊断肿瘤的方法，所述方法包括确定至少一种靶标的水平作为患者样品中的生物标志物，所述生物标志物的水平指示肿瘤细胞的存在。

    System and method for cutting and splicing polymeric webs
    5.
    发明授权
    System and method for cutting and splicing polymeric webs 失效
    用于切割和拼接聚合物网的系统和方法

    公开(公告)号：US5632831A

    公开(公告)日：1997-05-27

    申请号：US286005

    申请日：1994-08-04

    申请人： Robert Stull

    发明人： Robert Stull

    IPC分类号： B29C65/00 ,  B29C65/08 ,  B29C65/74 ,  B29C65/78 ,  B65H21/02 ,  B65H26/02 ,  B32B31/18

    CPC分类号： B29C66/8362 ,  B29C65/086 ,  B29C65/7443 ,  B29C66/1122 ,  B29C66/43 ,  B29C66/81417 ,  B29C66/8167 ,  B65H21/02 ,  B65H26/02 ,  B29C65/743 ,  B29C65/7841 ,  B29C66/73921 ,  B65H2301/46327 ,  Y10T156/108

    摘要： An apparatus for forming a near-seamless splice between a first polymeric web portion and a second polymeric web portion includes a frame, a clamping mechanism for clamping the first polymeric web portion and the second polymeric web portion in a desired position of registration, a combined welding and cutting mechanism for simultaneously (a) welding the two web portions together by forming a weld line at which the two web portions are fused; and (b) cutting through the two web portions at the weld line. This creates a near-seamless splice between the two web portions. In another aspect of the invention, the apparatus is mounted on a portable carriage that permits a user to quickly and easily move the entire apparatus into and out of position on a production line. The invention has particular utility for removing defective portions from a printed polymeric web having a repeating pattern thereon, such as the wrapping that is used for packaging absorbent consumer paper products such as paper towels and napkins.

    摘要翻译： 用于在第一聚合物纤维网部分和第二聚合物纤维网部分之间形成接近无缝接头的装置包括框架，用于将所述第一聚合物纤维网部分和所述第二聚合物纤维网部分夹持在所需的配准位置的夹紧机构， 焊接和切割机构，用于同时（a）通过形成两个腹板部分熔合的焊接线将两个腹板部分焊接在一起; 和（b）在焊接线切割两个腹板部分。 这将在两个网页部分之间产生近乎无缝的拼接。 在本发明的另一方面，该装置安装在便携式托架上，该便携式托架允许用户快速且容易地将整个装置移动到生产线上和离开生产线的位置。 本发明特别适用于从其上具有重复图案的印刷聚合物网上去除缺陷部分，例如用于包装吸收性消费纸产品如纸巾和餐巾的包装。