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公开(公告)号：US09107569B2
公开(公告)日：2015-08-18
申请号：US14004907
申请日：2012-03-12
Applicant: Vipin Gupta , Caifeng Shan , Pallavi Vajinepalli , Payal Keswarpu , Marinus Bastiaan Van Leeuwen , Celine Firtion , Shankar Mosur Venkatesan , Jelte Peter Vink
Inventor： Vipin Gupta , Caifeng Shan , Pallavi Vajinepalli , Payal Keswarpu , Marinus Bastiaan Van Leeuwen , Celine Firtion , Shankar Mosur Venkatesan , Jelte Peter Vink
CPC classification number: A61B1/00009 , A61B1/303 , G06T7/0016 , G06T2207/10016 , G06T2207/10021 , G06T2207/10056 , G06T2207/20036 , G06T2207/20081 , G06T2207/30004 , G06T2207/30096
Abstract: The invention provides for a medical instrument for examining the cervix comprising an optical examination system, a processor for controlling the medical instrument, and a memory containing machine executable instructions. Execution of the instructions causes the processor to: acquire a cervical image using the optical examination system; calculate a set of interest point locations using a digital filter; calculate a filtered set of interest point locations using the set of interest point locations and a morphological filter; calculate a reduced set of interest points locations using the filtered set of interest point locations and a neighborhood based filter; calculate a classified set of interest point locations reduced set of interest points and a trained classification module; calculate a set of punctation locations using the classified set of interest point locations and a second neighborhood based filter; and calculate punctation mark regions using the punctation point locations.
Abstract translation: 本发明提供一种用于检查子宫颈的医疗器械，包括光学检查系统，用于控制医疗器械的处理器和包含机器可执行指令的存储器。 执行指令使处理器：使用光学检查系统获取子宫颈图像; 使用数字滤波器计算一组感兴趣点位置; 使用所述一组兴趣点位置和形态滤波器来计算滤波的一组感兴趣点位置; 使用滤波的感兴趣点集合和基于邻域的滤波器来计算减少的兴趣点位置集合; 计算一组分类的兴趣点位置，减少一组兴趣点和一个训练有素的分类模块; 使用分类的兴趣点位置集合和第二邻域滤波器来计算一组标点位置; 并使用点标点位置来计算标点区域。
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2.发明申请METHOD FOR AUTOMATICALLY ADJUSTING A FOCAL PLANE OF A DIGITAL PATHOLOGY IMAGE 有权自动调整数字病理学图像的焦点平面的方法公开(公告)号：US20140169655A1
公开(公告)日：2014-06-19
申请号：US14232099
申请日：2012-06-28
Applicant: Marinus Bastiaan Van Leeuwen , Jelta Peter Vink
Inventor： Marinus Bastiaan Van Leeuwen , Jelta Peter Vink
IPC: G06T7/00
CPC classification number: G06T7/0012 , G02B21/16 , G02B21/244 , G06T5/50 , G06T2207/10056 , G06T2207/10148 , G06T2207/20092 , G06T2207/30024
Abstract: The present invention provides for an intelligent autofocus method and device for a digital pathology image, method are device are able to couple a feedback from the behaviour of the user, for example by gaze tracking arrangement, to the actually focal representation of an image and adjust the imaging setup accordingly with regard to the focal plane. The adjustment is performed in such a way that the focal plane is selected which optimizes and sharpens the actual object of interest which was previously determined.
Abstract translation: 本发明提供一种用于数字病理图像的智能自动对焦方法和装置，方法是能够将来自用户的行为的反馈（例如通过凝视跟踪布置）耦合到图像的实际焦点表示并且调整 成像设置相应于焦平面。 以这样的方式进行调整，使得选择焦平面，其优化并且锐化了先前确定的感兴趣的实际对象。
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公开(公告)号：US20140005477A1
公开(公告)日：2014-01-02
申请号：US14004907
申请日：2012-03-12
Applicant: Vipin Gupta , Caifeng Shan , Pallavi Vajinepalli , Payal Keswarpu , Marinus Bastiaan Van Leeuwen , Celine Firtion , Shankar Mosur Venkatesan , Jelte Peter Vink
Inventor： Vipin Gupta , Caifeng Shan , Pallavi Vajinepalli , Payal Keswarpu , Marinus Bastiaan Van Leeuwen , Celine Firtion , Shankar Mosur Venkatesan , Jelte Peter Vink
IPC: A61B1/00
CPC classification number: A61B1/00009 , A61B1/303 , G06T7/0016 , G06T2207/10016 , G06T2207/10021 , G06T2207/10056 , G06T2207/20036 , G06T2207/20081 , G06T2207/30004 , G06T2207/30096
Abstract: The invention provides for a medical instrument for examining the cervix comprising an optical examination system, a processor for controlling the medical instrument, and a memory containing machine executable instructions. Execution of the instructions causes the processor to: acquire a cervical image using the optical examination system; calculate a set of interest point locations using a digital filter; calculate a filtered set of interest point locations using the set of interest point locations and a morphological filter; calculate a reduced set of interest points locations using the filtered set of interest point locations and a neighborhood based filter; calculate a classified set of interest point locations reduced set of interest points and a trained classification module; calculate a set of punctation locations using the classified set of interest point locations and a second neighborhood based filter; and calculate punctation mark regions using the punctation point locations.
Abstract translation: 本发明提供一种用于检查子宫颈的医疗器械，包括光学检查系统，用于控制医疗器械的处理器和包含机器可执行指令的存储器。 执行指令使处理器：使用光学检查系统获取子宫颈图像; 使用数字滤波器计算一组兴趣点位置; 使用所述一组兴趣点位置和形态滤波器来计算滤波的一组感兴趣点位置; 使用滤波的感兴趣点集合和基于邻域的滤波器来计算减少的兴趣点位置集合; 计算一组分类的兴趣点位置，减少一组兴趣点和一个训练有素的分类模块; 使用分类的兴趣点位置集合和第二邻域滤波器来计算一组标点位置; 并使用点标点位置来计算标点区域。
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4.发明授权公开(公告)号：US09373168B2
公开(公告)日：2016-06-21
申请号：US14232099
申请日：2012-06-28
Applicant: Marinus Bastiaan Van Leeuwen , Jelte Peter Vink
Inventor： Marinus Bastiaan Van Leeuwen , Jelte Peter Vink
CPC classification number: G06T7/0012 , G02B21/16 , G02B21/244 , G06T5/50 , G06T2207/10056 , G06T2207/10148 , G06T2207/20092 , G06T2207/30024
Abstract: An intelligent autofocus method and device for a digital pathology image, method are device are able to couple a feedback from the behavior of the user, for example by gaze tracking arrangement, to the actually focal representation of an image and adjust the imaging setup accordingly with regard to the focal plane. The adjustment is performed in such a way that the focal plane is selected which optimizes and sharpens the actual object of interest which was previously determined.
Abstract translation: 用于数字病理图像的智能自动对焦方法和装置，装置能够将来自用户的行为的反馈（例如通过凝视跟踪布置）耦合到图像的实际焦点表示，并相应地调整成像设置， 考虑焦平面。 以这样的方式进行调整，使得选择焦平面，其优化并且锐化了先前确定的感兴趣的实际对象。
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